Asunto(s)
Trombosis Intracraneal , Trombosis de los Senos Intracraneales , Anticoagulantes/uso terapéutico , Encéfalo/diagnóstico por imagen , Vacunas contra la COVID-19/efectos adversos , Procedimientos Endovasculares , Heparina/uso terapéutico , Humanos , Trombosis Intracraneal/diagnóstico , Trombosis Intracraneal/etiología , Trombosis Intracraneal/fisiopatología , Trombosis Intracraneal/terapia , Angiografía por Resonancia Magnética , Guías de Práctica Clínica como Asunto , Pronóstico , Trombosis de los Senos Intracraneales/diagnóstico , Trombosis de los Senos Intracraneales/fisiopatología , Trombosis de los Senos Intracraneales/terapia , Tomografía Computarizada por Rayos XAsunto(s)
Enfermedades del Sistema Nervioso Periférico , Enfermedades Autoinmunes/complicaciones , Enfermedad Celíaca/complicaciones , Ganglios Sensoriales/patología , Humanos , Inmunoterapia , Infecciones/complicaciones , Síndromes Paraneoplásicos del Sistema Nervioso , Enfermedades del Sistema Nervioso Periférico/diagnóstico , Enfermedades del Sistema Nervioso Periférico/etiología , Enfermedades del Sistema Nervioso Periférico/terapia , Síndrome de Sjögren/complicacionesAsunto(s)
Absceso Epidural/complicaciones , Compresión de la Médula Espinal/terapia , Traumatismos de la Médula Espinal/complicaciones , Neoplasias de la Columna Vertebral/complicaciones , Enfermedad Aguda , Absceso Epidural/terapia , Humanos , Compresión de la Médula Espinal/diagnóstico , Compresión de la Médula Espinal/etiología , Traumatismos de la Médula Espinal/diagnóstico , Traumatismos de la Médula Espinal/terapia , Neoplasias de la Columna Vertebral/diagnóstico por imagen , Neoplasias de la Columna Vertebral/terapia , Columna Vertebral/diagnóstico por imagen , Índices de Gravedad del TraumaRESUMEN
Agraphesthesia has been attributed to impairment of the ability to detect more rudimentary directionality of lines written on the skin (directional cutaneous kinesthesia). We examined a patient who had a dissociation between preserved perception of line directionality and the loss of graphesthesia for letters and numbers. A man with a metastatic right parietal lesion was tested for the ability to determine the directionality of lines drawn on the palms and forehead and then evaluated for recognition of letters and numbers in these regions. Our patient could identify the directions of lines, letters and numbers drawn on paper. The ability to detect the direction and shape of lines drawn on the skin of the palms and on the forehead was preserved but he had agraphesthesia for numbers and letters in these same locations. The finding of isolated agraphesthesia for letters and numbers may be assigned to damage in the right parietal lobe. It represents a deficit of somatosensory processing that is of a higher order than detection of line directionality. The term "tactile asymbolia" may capture the dissociation. These clinical findings suggest that tactile cortex in humans, like visual cortex, may be hierarchically organized, as has been demonstrated in primates.
Asunto(s)
Neoplasias Encefálicas/complicaciones , Trastornos de la Sensación/etiología , Corteza Somatosensorial/patología , Neoplasias Encefálicas/patología , Femenino , Humanos , Masculino , Piel/inervación , Tacto , Percepción del Tacto/fisiologíaRESUMEN
Most peripheral neuropathies result from systemic disease. In this review, the authors highlight the main clinical features, electrographic abnormalities, histopathological aspects and treatment, as well as the current, but still incomplete understanding of the pathophysiological mechanisms involved. The peripheral neuropathic manifestations of renal failure, gastrointestinal illness, bariatric surgery, thyroid dysfunction, connective tissue disease, certain viral and bacterial infections, and critical illness are emphasized.