ADAPTAÇÃO TRANSCULTURAL E CONFIABILIDADE DO ACTIVE AUSTRALIA QUESTIONNAIRE PARA IDOSOS / CROSS-CULTURAL ADAPTATION AND RELIABILITY OF THE ACTIVE AUSTRALIA QUESTIONNAIRE FOR THE ELDERLY / ADAPTACIÓN TRANSCULTURAL Y FIABILIDAD DEL ACTIVE AUSTRALIA QUESTIONNAIRE PARA ANCIANOS

RESUMO Introdução: A atividade física é um importante parâmetro a ser quantificado em idosos. São necessários instrumentos de medida confiáveis para avaliar e elaborar metas de intervenções terapêuticas efetivas e verificar a evolução do paciente. Objetivo: Adaptar transculturalmente e determinar a confiabilidade teste-reteste e interexaminadores do Active Australia Questionnaire em idosos da comunidade. Métodos: A adaptação transcultural foi realizada de acordo com os critérios propostos por Guillemin e Beaton, a saber, tradução, retrotradução, síntese das traduções, apresentação ao comitê de especialistas e aplicação da versão pré-final para testar o questionário. Para a confiabilidade teste-reteste foi dado um intervalo de quatro horas para as coletas e um intervalo de seis horas para a análise interexaminador, após o reteste. Foram consideradas as informações de atividade física nos últimos sete dias. A caracterização da amostra foi feita pela análise descritiva. Para a análise da confiabilidade utilizou-se o coeficiente de correlação intraclasse (CCI). Participaram do estudo 22 idosos (72,5 ± 5,3 anos) e com 7,6 ± 3,9 anos de escolaridade. Resultados: A confiabilidade teste-reteste foi CCI = 0,97 e interexaminadores CCI = 0,82. Conclusão: O instrumento mostrou-se semântica e linguisticamente adequado e confiável, para avaliar o nível de atividade física em idosos na comunidade.

ABSTRACT Introduction: Physical activity is an important parameter to be quantified in the elderly. Reliable measurement instruments are needed to evaluate, and design effective therapeutic intervention targets and to monitor patient outcomes. Objective: To adapt cross-culturally and determine the test-retest and inter-rater reliability of the Active Australia Questionnaire in community elders. Methods: A cross-cultural adaptation was performed according to the criteria proposed by Guillemin and Beaton, namely, translation, back-translation, synthesis of translations, submission to the expert committee and implementation of the pre-final version to test the questionnaire. For test-retest reliability, a four-hour interval was given for collection, and a six-hour interval for inter-rater analysis, following the retest. Physical activity information was considered in the last seven days. The characterization of the sample was done by descriptive analysis. For the analysis of reliability we used the intraclass correlation coefficient (ICC). The study included 22 elderly (72.5 ± 5.3 years) and 7.6 ± 3.9 years of education. Results: Test-retest reliability was ICC = 0.97 and the inter-rater reliability was ICC= 0.82. Conclusion: The instrument was semantically and linguistically adequate and reliable to evaluate the level of physical activity in the elderly in the community.

RESUMEN Introducción: La actividad física es un parámetro importante a ser cuantificado en los ancianos. Son necesarias herramientas de medición fiables para evaluar y desarrollar los objetivos de las intervenciones terapéuticas eficaces y comprobar el progreso del paciente. Objetivo: Adaptar culturalmente y determinar la fiabilidad test-retest y entre los evaluadores del Active Australia Questionnaire en ancianos de la comunidad. Métodos: Una adaptación cultural se llevó a cabo de acuerdo con los criterios propuestos por Guillemin y Beaton, a saber, traducción, traducción inversa, síntesis de las traducciones, presentación al comité de expertos y aplicación de la versión pre-final para poner a prueba el cuestionario. Para la fiabilidad del test-retest fue dado un intervalo de cuatro horas para la recolección y un intervalo de seis horas para el análisis entre evaluadores, después del retest. La información sobre la actividad física fue considerada en los últimos siete días. La caracterización de la muestra se realizó mediante el análisis descriptivo. Para el análisis de fiabilidad se utilizó el coeficiente de correlación intraclase (CCI). El estudio incluyó a 22 ancianos (72,5 ± 5,3 años) y 7,6 ± 3,9 años de estudio. Resultados: La fiabilidad test-retest fue CCI = 0,97 y entre evaluadores fue CCI = 0,82. Conclusión: El instrumento resultó ser semánticamente y lingüísticamente apropiado y fiable para evaluar el nivel de actividad física de los ancianos en la comunidad.

Inflammatory Mediators and Pain in the First Year After Acute Episode of Low-Back Pain in Elderly Women: Longitudinal Data from Back Complaints in the Elders-Brazil.

OBJECTIVE: The aims of this study were to determine the course of plasma levels of inflammatory mediators (interleukin 6 [IL-6], tumor necrosis factor α [TNF-α], soluble TNF receptor 1 [sTNF-R1]) and the severity of low-back pain (LBP) over 6 to 12 months after an acute episode of LBP in elderly women and to establish an association between inflammatory mediators and LBP recovery. DESIGN: This was a longitudinal study of a subsample (155 elderly women with acute LBP, aged ≥65 years) of the international Back Complaints in the Elders cohort study. Plasma levels of IL-6, TNF-α, and sTNF-R1 were measured using enzyme-linked immunosorbent assays and pain severity using the numerical pain scale. RESULTS: There was a decrease in the severity of LBP (P = 0.033) and in the levels of IL-6 and TNF-α (P < 0.001) and an increase in sTNF-R1 (P < 0.001) in the first year after an acute episode of LBP. The probability of occurrence of pain relief at the 12-month follow-up was 2.22 times higher in elderly women who had low levels of IL-6 (<1.58 pg/mL) at baseline. CONCLUSIONS: Our findings showed a relationship between inflammation and LBP by establishing that low IL-6 plasma levels preceded outcome (LBP recovery), supporting the concept that proinflammatory cytokines promote pain.

Association Between the Plasma Levels of Mediators of Inflammation With Pain and Disability in the Elderly With Acute Low Back Pain: Data From the Back Complaints in the Elders (BACE)-Brazil Study.

STUDY DESIGN: Cross-sectional study with subsample of elderly women with acute low back pain (LBP), from Back Complaints in the Elders-Brazil (BACE-Brazil) OBJECTIVE: To investigate the association between plasma levels of mediators of inflammation (interleukin-1 beta (IL-1ß), IL-6, tumor necrosis factor alpha (TNF-α), and soluble TNF receptor 1 (sTNF-R1)) with pain and disability experienced by elderly women with acute LBP. SUMMARY OF BACKGROUND DATA: Among the elderly, LBP is a complaint of great importance and can lead to disability. Inflammatory cytokines are elevated in painful conditions, and may promote pain. METHODS: We included 155 community-dwelling elderly women (age ≥ 65 yr), who presented with a new (acute) episode of LBP. Enzyme-linked immunosorbent assays were used to measure TNF-α, sTNF-R1, IL-1ß, and IL-6. Disability was assessed using the Roland Morris Disability Questionnaire; pain was assessed using the McGill Pain Questionnaire. Linear regression models were fit with each pain and disability outcome as dependent variables: Present Pain Intensity; Qualities of pain; Severity of pain in the last week; LBP frequency and disability. RESULTS: Depressive symptoms and IL-6 were associated and explained 20.9% of "qualities of pain" variability. TNF-α, sTNFR1, education, body mass index, and depressive symptoms explained 8.4% of "Severity of pain in the past week" variability. TNF-α, education, BMI, depressive symptoms, present pain intensity, qualities of pain, and LBP frequency explained 48.6% of "disability." No associations between inflammatory cytokines and "present pain intensity" and "LBP frequency" were found. CONCLUSION: Our results demonstrate associations between inflammatory markers (TNF-α and sTNFR1) and pain severity, IL-6 was associated with the qualities of pain, and TNF-α was also associated with disability. These inflammatory mediators represent new markers to be considered in the assessment and treatment of elderly patients with LBP. LEVEL OF EVIDENCE: 5.

Psychometric properties of the Brazilian version of the Pain Catastrophizing Scale for acute low back pain.

Measurement instruments of pain catastrophizing for middle-aged and elderly individuals are needed to understand its impact on low back pain. The goals were to cross-culturally adapt the Pain Catastrophizing Scale, assess the construct validity through Rasch analysis, and verify reliability and convergent validity of pain catastrophizing with psychosocial factors. 131 individuals aged 55 years and older with acute low back pain were interviewed . The intra-rater reliability was Kp = 0.80 and interrater Kp = 0.75. The Rasch analysis found adequate reliability coefficients (0.95 for items and 0.90 for individuals ). The separation index for the elderly was 2.95 and 4.59 items. Of the 13 items, one did not fit the model, which was justified in the sample evaluated. The pain catastrophizing correlated with most psychosocial factors. The instrument proved to be clinically useful. Subsequent studies should carry out the same analysis in different populations.

Psychometric properties of the Brazilian version of the Pain Catastrophizing Scale for acute low back pain / Propriedades psicométricas da versão brasileira da Escala de Catastrofização da Dor para dor lombar aguda

Measurement instruments of pain catastrophizing for middle-aged and elderly individuals are needed to understand its impact on low back pain. The goals were to cross-culturally adapt the Pain Catastrophizing Scale, assess the construct validity through Rasch analysis, and verify reliability and convergent validity of pain catastrophizing with psychosocial factors. 131 individuals aged 55 years and older with acute low back pain were interviewed . The intra-rater reliability was Kp = 0.80 and interrater Kp = 0.75. The Rasch analysis found adequate reliability coefficients (0.95 for items and 0.90 for individuals ). The separation index for the elderly was 2.95 and 4.59 items. Of the 13 items, one did not fit the model, which was justified in the sample evaluated. The pain catastrophizing correlated with most psychosocial factors. The instrument proved to be clinically useful. Subsequent studies should carry out the same analysis in different populations.

Instrumentos de medida da catastrofização da dor para indivíduos de meia-idade e idosos são necessários para compreensão do impacto na dor lombar nessa população. Os objetivos foram adaptar transculturalmente a Escala de Catastrofização da Dor, avaliar a validade de construto pela análise Rasch, verificar a confiabilidade e a validade convergente da catastrofização da dor com fatores psicossociais. Participaram 131 indivíduos comunitários com 55 anos e mais com dor lombar aguda. A confiabilidade intra-examinadores foi de Kp = 0,80 e inter-examinadores Kp = 0,75. A análise Rasch, detectou adequados coeficientes de confiabilidade (0,95 para itens e 0,90 para indivíduos). O índice de separação dos idosos foi de 2,95 e dos itens 4,59. Dos 13 itens, um não se enquadrou no modelo, o que se justificou na amostra avaliada. A catastrofização da dor se correlacionou com a maioria dos fatores psicossociais. O instrumento mostrou-se clinicamente útil. Estudos subsequentes devem proceder às mesmas análises em diferentes populações.

Functional performance and plasma cytokine levels in elderly women with and without low back pain.

BACKGROUND AND OBJECTIVES: Low back pain (LBP) is a complaint of great importance among the elderly due to its significant impact on function. LBP could contribute to changes in the regulatory process of inflammatory mediators observed in elders. The aim of this study was to compare plasma levels of interleukin(IL)-6, soluble tumor necrosis factor receptor 1(sTNF-R1), and functionality among 3 groups of elderly women: GI, with LBP; GII, without LBP but reports of other pain; and GIII, without any reported pain. MATERIAL AND METHOD: This was an observational study of a subsample of the international Back Complaints in the Elders cohort study. IL-6 and sTNF-R1 were measured using the enzyme-linked immunosorbent assay. Functionality was assessed using the Timed Up and Go, gait speed and Roland Morris Disability Questionnaire; and pain, using the numerical pain scale. RESULTS: Two hundred and thirteen women aged 71.35 ± 4.76 years were included. GI presented the highest sTNF-R1 levels (p=0.016), worst TUG performance (p< 0.001) and slowest gait speed (p< 0.01) compared to GII and GIII, which were similar (p > 0.05). No difference was found between the IL-6 plasma levels in any of the groups. CONCLUSION: Elderly women with LBP had the highest sTNF-R1 plasma levels and the worst functional performance compared to elderly women with reports of other pain (not LBP) or no pain.