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2.
Johns Hopkins Med J ; 150(2): 51-4, 1982 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-7057619

RESUMEN

In two otherwise normal male subjects selected for normal serum cholesterol and triglycerides but low serum high-density lipoprotein (HDL) levels, oral administration of 1 g per day of L-carnitine over a period of 10-15 weeks caused a substantial increase in high-density lipoprotein levels, as well as a decrease in serum triglycerides. The ratio of HDL-cholesterol to total cholesterol increased, but this change was not due to an obligatory lowering of total cholesterol. Possible mechanisms of the carnitine effect are discussed. Since elevated high-density lipoprotein levels significantly reduce the risk of arteriosclerotic cardiovascular disease, this action of carnitine deserves further study.


Asunto(s)
Carnitina/farmacología , Colesterol/sangre , Lipoproteínas HDL/sangre , HDL-Colesterol , Humanos , Lípidos/sangre , Masculino , Persona de Mediana Edad , Triglicéridos/sangre
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