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1.
Artículo en Inglés | MEDLINE | ID: mdl-38848228

RESUMEN

Imitation learning (IL) is a well-known problem in the field of Markov decision process (MDP), where one is given multiple demonstration trajectories generated by expert(s), and the goal is to replicate the hidden expert-policies so that when the MDP is run independently, it generates trajectories close to the demonstrated ones. IL is one of the most useful tools used in building versatile robots that can learn from examples. This task becomes particularly challenging when the expert exhibits a mixture of behavior modes. Prior work has introduced latent variables to model variations of the expert policy. However, our experiments show that the existing works do not exhibit appropriate imitation of individual modes. To tackle this problem, we first draw inspiration from the well-known classical technique of self-organizing maps (SOMs) and introduce an encoder-free generative model-referred to as the self-organizing generative (SOG) model-for learning multimodal data distributions from samples. We then apply SOG for behavior cloning (BC)-a framework that learns deterministic policies without considering the environment-to accurately distinguish and imitate different modes. Then, we integrate it with generative adversarial IL (GAIL)-a framework that learns policies while considering the environment-to make the learning robust toward compounding errors at unseen states. We show that our method significantly outperforms the state of the art across multiple experiments within the MuJoCo simulator, including locomotion and robotic manipulation tasks.

2.
J Neural Eng ; 21(3)2024 May 28.
Artículo en Inglés | MEDLINE | ID: mdl-38722308

RESUMEN

Objective. This study aims to develop and validate an end-to-end software platform, PyHFO, that streamlines the application of deep learning (DL) methodologies in detecting neurophysiological biomarkers for epileptogenic zones from EEG recordings.Approach. We introduced PyHFO, which enables time-efficient high-frequency oscillation (HFO) detection algorithms like short-term energy and Montreal Neurological Institute and Hospital detectors. It incorporates DL models for artifact and HFO with spike classification, designed to operate efficiently on standard computer hardware.Main results. The validation of PyHFO was conducted on three separate datasets: the first comprised solely of grid/strip electrodes, the second a combination of grid/strip and depth electrodes, and the third derived from rodent studies, which sampled the neocortex and hippocampus using depth electrodes. PyHFO demonstrated an ability to handle datasets efficiently, with optimization techniques enabling it to achieve speeds up to 50 times faster than traditional HFO detection applications. Users have the flexibility to employ our pre-trained DL model or use their EEG data for custom model training.Significance. PyHFO successfully bridges the computational challenge faced in applying DL techniques to EEG data analysis in epilepsy studies, presenting a feasible solution for both clinical and research settings. By offering a user-friendly and computationally efficient platform, PyHFO paves the way for broader adoption of advanced EEG data analysis tools in clinical practice and fosters potential for large-scale research collaborations.


Asunto(s)
Aprendizaje Profundo , Electroencefalografía , Electroencefalografía/métodos , Electroencefalografía/instrumentación , Animales , Ratas , Algoritmos , Epilepsia/fisiopatología , Epilepsia/diagnóstico , Programas Informáticos , Humanos , Hipocampo/fisiología
3.
PLoS One ; 19(2): e0298789, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38394225

RESUMEN

A key metric to determine the performance of a stock in a market is its return over different investment horizons (τ). Several works have observed heavy-tailed behavior in the distributions of returns in different markets, which are observable indicators of underlying complex dynamics. Such prior works study return distributions that are marginalized across the individual stocks in the market, and do not track statistics about the joint distributions of returns conditioned on different stocks, which would be useful for optimizing inter-stock asset allocation strategies. As a step towards this goal, we study emergent phenomena in the distributions of returns as captured by their pairwise correlations. In particular, we consider the pairwise (between stocks i, j) partial correlations of returns with respect to the market mode, ci,j(τ), (thus, correcting for the baseline return behavior of the market), over different time horizons (τ), and discover two novel emergent phenomena: (i) the standardized distributions of the ci,j(τ)'s are observed to be invariant of τ ranging from from 1000min (2.5 days) to 30000min (2.5 months); (ii) the scaling of the standard deviation of ci,j(τ)'s with τ admits good fits to simple model classes such as a power-law τ-λ or stretched exponential function [Formula: see text] (λ, ß > 0). Moreover, the parameters governing these fits provide a summary view of market health: for instance, in years marked by unprecedented financial crises-for example 2008 and 2020-values of λ (scaling exponent) are substantially lower. Finally, we demonstrate that the observed emergent behavior cannot be adequately supported by existing generative frameworks such as single- and multi-factor models. We introduce a promising agent-based Vicsek model that closes this gap.


Asunto(s)
Inversiones en Salud , Modelos Económicos , Humanos , Alimentos Formulados , Hospitalización , Lenguaje
4.
Science ; 382(6668): 263-264, 2023 Oct 20.
Artículo en Inglés | MEDLINE | ID: mdl-37856601

RESUMEN

A chip design integrates computation and memory to efficiently process data at low energy cost.

5.
Phys Rev Lett ; 131(6): 067301, 2023 Aug 11.
Artículo en Inglés | MEDLINE | ID: mdl-37625061

RESUMEN

We present the interpretable meta neural ordinary differential equation (iMODE) method to rapidly learn generalizable (i.e., not parameter-specific) dynamics from trajectories of multiple dynamical systems that vary in their physical parameters. The iMODE method learns metaknowledge, the functional variations of the force field of dynamical system instances without knowing the physical parameters, by adopting a bilevel optimization framework: an outer level capturing the common force field form among studied dynamical system instances and an inner level adapting to individual system instances. A priori physical knowledge can be conveniently embedded in the neural network architecture as inductive bias, such as conservative force field and Euclidean symmetry. With the learned metaknowledge, iMODE can model an unseen system within seconds, and inversely reveal knowledge on the physical parameters of a system, or as a neural gauge to "measure" the physical parameters of an unseen system with observed trajectories. iMODE can be generally applied to a dynamical system of an arbitrary type or number of physical parameters and is validated on bistable, double pendulum, Van der Pol, Slinky, and reaction-diffusion systems.

6.
Clin Neurophysiol ; 154: 129-140, 2023 10.
Artículo en Inglés | MEDLINE | ID: mdl-37603979

RESUMEN

OBJECTIVE: This study aimed to explore sensitive detection methods for pathological high-frequency oscillations (HFOs) to improve seizure outcomes in epilepsy surgery. METHODS: We analyzed interictal HFOs (80-500 Hz) in 15 children with medication-resistant focal epilepsy who underwent chronic intracranial electroencephalogram via subdural grids. The HFOs were assessed using the short-term energy (STE) and Montreal Neurological Institute (MNI) detectors and examined for spike association and time-frequency plot characteristics. A deep learning (DL)-based classification was applied to purify pathological HFOs. Postoperative seizure outcomes were correlated with HFO-resection ratios to determine the optimal HFO detection method. RESULTS: The MNI detector identified a higher percentage of pathological HFOs than the STE detector, but some pathological HFOs were detected only by the STE detector. HFOs detected by both detectors had the highest spike association rate. The Union detector, which detects HFOs identified by either the MNI or STE detector, outperformed other detectors in predicting postoperative seizure outcomes using HFO-resection ratios before and after DL-based purification. CONCLUSIONS: HFOs detected by standard automated detectors displayed different signal and morphological characteristics. DL-based classification effectively purified pathological HFOs. SIGNIFICANCE: Enhancing the detection and classification methods of HFOs will improve their utility in predicting postoperative seizure outcomes.


Asunto(s)
Aprendizaje Profundo , Epilepsia Refractaria , Epilepsia , Niño , Humanos , Epilepsia/diagnóstico , Epilepsia/cirugía , Convulsiones , Electroencefalografía/métodos , Epilepsia Refractaria/diagnóstico , Epilepsia Refractaria/cirugía
7.
Proc Natl Acad Sci U S A ; 120(31): e2212660120, 2023 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-37490536

RESUMEN

Variational Bayes (VB) inference algorithm is used widely to estimate both the parameters and the unobserved hidden variables in generative statistical models. The algorithm-inspired by variational methods used in computational physics-is iterative and can get easily stuck in local minima, even when classical techniques, such as deterministic annealing (DA), are used. We study a VB inference algorithm based on a nontraditional quantum annealing approach-referred to as quantum annealing variational Bayes (QAVB) inference-and show that there is indeed a quantum advantage to QAVB over its classical counterparts. In particular, we show that such better performance is rooted in key quantum mechanics concepts: i) The ground state of the Hamiltonian of a quantum system-defined from the given data-corresponds to an optimal solution for the minimization problem of the variational free energy at very low temperatures; ii) such a ground state can be achieved by a technique paralleling the quantum annealing process; and iii) starting from this ground state, the optimal solution to the VB problem can be achieved by increasing the heat bath temperature to unity, and thereby avoiding local minima introduced by spontaneous symmetry breaking observed in classical physics based VB algorithms. We also show that the update equations of QAVB can be potentially implemented using ⌈logK⌉ qubits and 𝒪(K) operations per step, where K is the number of values hidden categorical variables can take. Thus, QAVB can match the time complexity of existing VB algorithms, while delivering higher performance.

8.
medRxiv ; 2023 Apr 17.
Artículo en Inglés | MEDLINE | ID: mdl-37131743

RESUMEN

Objective: This study aimed to explore sensitive detection methods and deep learning (DL)-based classification for pathological high-frequency oscillations (HFOs). Methods: We analyzed interictal HFOs (80-500 Hz) in 15 children with medication-resistant focal epilepsy who underwent resection after chronic intracranial electroencephalogram via subdural grids. The HFOs were assessed using the short-term energy (STE) and Montreal Neurological Institute (MNI) detectors and examined for pathological features based on spike association and time-frequency plot characteristics. A DL-based classification was applied to purify pathological HFOs. Postoperative seizure outcomes were correlated with HFO-resection ratios to determine the optimal HFO detection method. Results: The MNI detector identified a higher percentage of pathological HFOs than the STE detector, but some pathological HFOs were detected only by the STE detector. HFOs detected by both detectors exhibited the most pathological features. The Union detector, which detects HFOs identified by either the MNI or STE detector, outperformed other detectors in predicting postoperative seizure outcomes using HFO-resection ratios before and after DL-based purification. Conclusions: HFOs detected by standard automated detectors displayed different signal and morphological characteristics. DL-based classification effectively purified pathological HFOs. Significance: Enhancing the detection and classification methods of HFOs will improve their utility in predicting postoperative seizure outcomes. HIGHLIGHTS: HFOs detected by the MNI detector showed different traits and higher pathological bias than those detected by the STE detectorHFOs detected by both MNI and STE detectors (the Intersection HFOs) were deemed the most pathologicalA deep learning-based classification was able to distill pathological HFOs, regard-less of the initial HFO detection methods.

9.
Sci Rep ; 13(1): 651, 2023 01 12.
Artículo en Inglés | MEDLINE | ID: mdl-36635322

RESUMEN

Extracting meaning from a dynamic and variable flow of incoming information is a major goal of both natural and artificial intelligence. Computer vision (CV) guided by deep learning (DL) has made significant strides in recognizing a specific identity despite highly variable attributes. This is the same challenge faced by the nervous system and partially addressed by the concept cells-neurons exhibiting selective firing in response to specific persons/places, described in the human medial temporal lobe (MTL) ⁠. Yet, access to neurons representing a particular concept is limited due to these neurons' sparse coding. It is conceivable, however, that the information required for such decoding is present in relatively small neuronal populations. To evaluate how well neuronal populations encode identity information in natural settings, we recorded neuronal activity from multiple brain regions of nine neurosurgical epilepsy patients implanted with depth electrodes, while the subjects watched an episode of the TV series "24". First, we devised a minimally supervised CV algorithm (with comparable performance against manually-labeled data) to detect the most prevalent characters (above 1% overall appearance) in each frame. Next, we implemented DL models that used the time-varying population neural data as inputs and decoded the visual presence of the four main characters throughout the episode. This methodology allowed us to compare "computer vision" with "neuronal vision"-footprints associated with each character present in the activity of a subset of neurons-and identify the brain regions that contributed to this decoding process. We then tested the DL models during a recognition memory task following movie viewing where subjects were asked to recognize clip segments from the presented episode. DL model activations were not only modulated by the presence of the corresponding characters but also by participants' subjective memory of whether they had seen the clip segment, and by the associative strengths of the characters in the narrative plot. The described approach can offer novel ways to probe the representation of concepts in time-evolving dynamic behavioral tasks. Further, the results suggest that the information required to robustly decode concepts is present in the population activity of only tens of neurons even in brain regions beyond MTL.


Asunto(s)
Inteligencia Artificial , Encéfalo , Humanos , Encéfalo/fisiología , Lóbulo Temporal/fisiología , Neuronas/fisiología , Computadores
10.
J Neural Eng ; 19(6)2022 12 07.
Artículo en Inglés | MEDLINE | ID: mdl-36541546

RESUMEN

Objective.Intracranially-recorded interictal high-frequency oscillations (HFOs) have been proposed as a promising spatial biomarker of the epileptogenic zone. However, HFOs can also be recorded in the healthy brain regions, which complicates the interpretation of HFOs. The present study aimed to characterize salient features of physiological HFOs using deep learning (DL).Approach.We studied children with neocortical epilepsy who underwent intracranial strip/grid evaluation. Time-series EEG data were transformed into DL training inputs. The eloquent cortex (EC) was defined by functional cortical mapping and used as a DL label. Morphological characteristics of HFOs obtained from EC (ecHFOs) were distilled and interpreted through a novel weakly supervised DL model.Main results.A total of 63 379 interictal intracranially-recorded HFOs from 18 children were analyzed. The ecHFOs had lower amplitude throughout the 80-500 Hz frequency band around the HFO onset and also had a lower signal amplitude in the low frequency band throughout a one-second time window than non-ecHFOs, resembling a bell-shaped template in the time-frequency map. A minority of ecHFOs were HFOs with spikes (22.9%). Such morphological characteristics were confirmed to influence DL model prediction via perturbation analyses. Using the resection ratio (removed HFOs/detected HFOs) of non-ecHFOs, the prediction of postoperative seizure outcomes improved compared to using uncorrected HFOs (area under the ROC curve of 0.82, increased from 0.76).Significance.We characterized salient features of physiological HFOs using a DL algorithm. Our results suggested that this DL-based HFO classification, once trained, might help separate physiological from pathological HFOs, and efficiently guide surgical resection using HFOs.


Asunto(s)
Aprendizaje Profundo , Epilepsia , Niño , Humanos , Electroencefalografía/métodos , Convulsiones , Encéfalo
11.
Sci Rep ; 12(1): 19520, 2022 Nov 14.
Artículo en Inglés | MEDLINE | ID: mdl-36376374

RESUMEN

The paradigm of variational quantum classifiers (VQCs) encodes classical information as quantum states, followed by quantum processing and then measurements to generate classical predictions. VQCs are promising candidates for efficient utilizations of noisy intermediate scale quantum (NISQ) devices: classifiers involving M-dimensional datasets can be implemented with only [Formula: see text] qubits by using an amplitude encoding. A general framework for designing and training VQCs, however, is lacking. An encouraging specific embodiment of VQCs, quantum circuit learning (QCL), utilizes an ansatz: a circuit with a predetermined circuit geometry and parametrized gates expressing a time-evolution unitary operator; training involves learning the gate parameters through a gradient-descent algorithm where the gradients themselves can be efficiently estimated by the quantum circuit. The representational power of QCL, however, depends strongly on the choice of the ansatz, as it limits the range of possible unitary operators that a VQC can search over. Equally importantly, the landscape of the optimization problem may have challenging properties such as barren plateaus and the associated gradient-descent algorithm may not find good local minima. Thus, it is critically important to estimate (i) the price of ansatz; that is, the gap between the performance of QCL and the performance of ansatz-independent VQCs, and (ii) the price of using quantum circuits as classical classifiers: that is, the performance gap between VQCs and equivalent classical classifiers. This paper develops a computational framework to address both these open problems. First, it shows that VQCs, including QCL, fit inside the well-known kernel method. Next it introduces a framework for efficiently designing ansatz-independent VQCs, which we call the unitary kernel method (UKM). The UKM framework enables one to estimate the first known computationally-determined bounds on both the price of ansatz and the price of any speedup advantages of VQCs: numerical results with datatsets of various dimensions, ranging from 4 to 256, show that the ansatz-induced gap can vary between 10 and 20[Formula: see text], while the VQC-induced gap (between VQC and kernel method) can vary between 10 and 16[Formula: see text]. To further understand the role of ansatz in VQCs, we also propose a method of decomposing a given unitary operator into a quantum circuit, which we call the variational circuit realization (VCR): given any parameterized circuit block (as for example, used in QCL), it finds optimal parameters and the number of layers of the circuit block required to approximate any target unitary operator with a given precision.

12.
Brain Commun ; 4(1): fcab267, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35169696

RESUMEN

Intracranially recorded interictal high-frequency oscillations have been proposed as a promising spatial biomarker of the epileptogenic zone. However, its visual verification is time-consuming and exhibits poor inter-rater reliability. Furthermore, no method is currently available to distinguish high-frequency oscillations generated from the epileptogenic zone (epileptogenic high-frequency oscillations) from those generated from other areas (non-epileptogenic high-frequency oscillations). To address these issues, we constructed a deep learning-based algorithm using chronic intracranial EEG data via subdural grids from 19 children with medication-resistant neocortical epilepsy to: (i) replicate human expert annotation of artefacts and high-frequency oscillations with or without spikes, and (ii) discover epileptogenic high-frequency oscillations by designing a novel weakly supervised model. The 'purification power' of deep learning is then used to automatically relabel the high-frequency oscillations to distill epileptogenic high-frequency oscillations. Using 12 958 annotated high-frequency oscillation events from 19 patients, the model achieved 96.3% accuracy on artefact detection (F1 score = 96.8%) and 86.5% accuracy on classifying high-frequency oscillations with or without spikes (F1 score = 80.8%) using patient-wise cross-validation. Based on the algorithm trained from 84 602 high-frequency oscillation events from nine patients who achieved seizure-freedom after resection, the majority of such discovered epileptogenic high-frequency oscillations were found to be ones with spikes (78.6%, P < 0.001). While the resection ratio of detected high-frequency oscillations (number of resected events/number of detected events) did not correlate significantly with post-operative seizure freedom (the area under the curve = 0.76, P = 0.06), the resection ratio of epileptogenic high-frequency oscillations positively correlated with post-operative seizure freedom (the area under the curve = 0.87, P = 0.01). We discovered that epileptogenic high-frequency oscillations had a higher signal intensity associated with ripple (80-250 Hz) and fast ripple (250-500 Hz) bands at the high-frequency oscillation onset and with a lower frequency band throughout the event time window (the inverted T-shaped), compared to non-epileptogenic high-frequency oscillations. We then designed perturbations on the input of the trained model for non-epileptogenic high-frequency oscillations to determine the model's decision-making logic. The model confidence significantly increased towards epileptogenic high-frequency oscillations by the artificial introduction of the inverted T-shaped signal template (mean probability increase: 0.285, P < 0.001), and by the artificial insertion of spike-like signals into the time domain (mean probability increase: 0.452, P < 0.001). With this deep learning-based framework, we reliably replicated high-frequency oscillation classification tasks by human experts. Using a reverse engineering technique, we distinguished epileptogenic high-frequency oscillations from others and identified its salient features that aligned with current knowledge.

13.
R Soc Open Sci ; 8(12): 210797, 2021 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-34950484

RESUMEN

Social reading sites offer an opportunity to capture a segment of readers' responses to literature, while data-driven analysis of these responses can provide new critical insight into how people 'read'. Posts discussing an individual book on the social reading site, Goodreads, are referred to as 'reviews', and consist of summaries, opinions, quotes or some mixture of these. Computationally modelling these reviews allows one to discover the non-professional discussion space about a work, including an aggregated summary of the work's plot, an implicit sequencing of various subplots and readers' impressions of main characters. We develop a pipeline of interlocking computational tools to extract a representation of this reader-generated shared narrative model. Using a corpus of reviews of five popular novels, we discover readers' distillation of the novels' main storylines and their sequencing, as well as the readers' varying impressions of characters in the novel. In so doing, we make three important contributions to the study of infinite-vocabulary networks: (i) an automatically derived narrative network that includes meta-actants; (ii) a sequencing algorithm, REV2SEQ, that generates a consensus sequence of events based on partial trajectories aggregated from reviews, and (iii) an 'impressions' algorithm, SENT2IMP, that provides multi-modal insight into readers' opinions of characters.

14.
J Comput Soc Sci ; 3(2): 279-317, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33134595

RESUMEN

Rumors and conspiracy theories thrive in environments of low confidence and low trust. Consequently, it is not surprising that ones related to the COVID-19 pandemic are proliferating given the lack of scientific consensus on the virus's spread and containment, or on the long-term social and economic ramifications of the pandemic. Among the stories currently circulating in US-focused social media forums are ones suggesting that the 5G telecommunication network activates the virus, that the pandemic is a hoax perpetrated by a global cabal, that the virus is a bio-weapon released deliberately by the Chinese, or that Bill Gates is using it as cover to launch a broad vaccination program to facilitate a global surveillance regime. While some may be quick to dismiss these stories as having little impact on real-world behavior, recent events including the destruction of cell phone towers, racially fueled attacks against Asian Americans, demonstrations espousing resistance to public health orders, and wide-scale defiance of scientifically sound public mandates such as those to wear masks and practice social distancing, countermand such conclusions. Inspired by narrative theory, we crawl social media sites and news reports and, through the application of automated machine-learning methods, discover the underlying narrative frameworks supporting the generation of rumors and conspiracy theories. We show how the various narrative frameworks fueling these stories rely on the alignment of otherwise disparate domains of knowledge, and consider how they attach to the broader reporting on the pandemic. These alignments and attachments, which can be monitored in near real time, may be useful for identifying areas in the news that are particularly vulnerable to reinterpretation by conspiracy theorists. Understanding the dynamics of storytelling on social media and the narrative frameworks that provide the generative basis for these stories may also be helpful for devising methods to disrupt their spread.

15.
PLoS One ; 15(6): e0233879, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32544200

RESUMEN

Although a great deal of attention has been paid to how conspiracy theories circulate on social media, and the deleterious effect that they, and their factual counterpart conspiracies, have on political institutions, there has been little computational work done on describing their narrative structures. Predicating our work on narrative theory, we present an automated pipeline for the discovery and description of the generative narrative frameworks of conspiracy theories that circulate on social media, and actual conspiracies reported in the news media. We base this work on two separate comprehensive repositories of blog posts and news articles describing the well-known conspiracy theory Pizzagate from 2016, and the New Jersey political conspiracy Bridgegate from 2013. Inspired by the qualitative narrative theory of Greimas, we formulate a graphical generative machine learning model where nodes represent actors/actants, and multi-edges and self-loops among nodes capture context-specific relationships. Posts and news items are viewed as samples of subgraphs of the hidden narrative framework network. The problem of reconstructing the underlying narrative structure is then posed as a latent model estimation problem. To derive the narrative frameworks in our target corpora, we automatically extract and aggregate the actants (people, places, objects) and their relationships from the posts and articles. We capture context specific actants and interactant relationships by developing a system of supernodes and subnodes. We use these to construct an actant-relationship network, which constitutes the underlying generative narrative framework for each of the corpora. We show how the Pizzagate framework relies on the conspiracy theorists' interpretation of "hidden knowledge" to link otherwise unlinked domains of human interaction, and hypothesize that this multi-domain focus is an important feature of conspiracy theories. We contrast this to the single domain focus of an actual conspiracy. While Pizzagate relies on the alignment of multiple domains, Bridgegate remains firmly rooted in the single domain of New Jersey politics. We hypothesize that the narrative framework of a conspiracy theory might stabilize quickly in contrast to the narrative framework of an actual conspiracy, which might develop more slowly as revelations come to light. By highlighting the structural differences between the two narrative frameworks, our approach could be used by private and public analysts to help distinguish between conspiracy theories and conspiracies.


Asunto(s)
Decepción , Descubrimiento del Conocimiento/métodos , Narración , Política , Medios de Comunicación Sociales , Programas Informáticos , Análisis de Datos , Humanos , Aprendizaje Automático , Estados Unidos
16.
Proc Natl Acad Sci U S A ; 116(1): 96-105, 2019 01 02.
Artículo en Inglés | MEDLINE | ID: mdl-30559207

RESUMEN

Despite significant recent progress, machine vision systems lag considerably behind their biological counterparts in performance, scalability, and robustness. A distinctive hallmark of the brain is its ability to automatically discover and model objects, at multiscale resolutions, from repeated exposures to unlabeled contextual data and then to be able to robustly detect the learned objects under various nonideal circumstances, such as partial occlusion and different view angles. Replication of such capabilities in a machine would require three key ingredients: (i) access to large-scale perceptual data of the kind that humans experience, (ii) flexible representations of objects, and (iii) an efficient unsupervised learning algorithm. The Internet fortunately provides unprecedented access to vast amounts of visual data. This paper leverages the availability of such data to develop a scalable framework for unsupervised learning of object prototypes-brain-inspired flexible, scale, and shift invariant representations of deformable objects (e.g., humans, motorcycles, cars, airplanes) comprised of parts, their different configurations and views, and their spatial relationships. Computationally, the object prototypes are represented as geometric associative networks using probabilistic constructs such as Markov random fields. We apply our framework to various datasets and show that our approach is computationally scalable and can construct accurate and operational part-aware object models much more efficiently than in much of the recent computer vision literature. We also present efficient algorithms for detection and localization in new scenes of objects and their partial views.


Asunto(s)
Inteligencia Artificial , Aprendizaje Automático no Supervisado , Algoritmos , Encéfalo/fisiología , Simulación por Computador , Reconocimiento Facial , Sistemas de Información Geográfica , Humanos , Reconocimiento Visual de Modelos , Percepción Visual
17.
JMIR Public Health Surveill ; 2(2): e166, 2016 Nov 22.
Artículo en Inglés | MEDLINE | ID: mdl-27876690

RESUMEN

BACKGROUND: Social media offer an unprecedented opportunity to explore how people talk about health care at a very large scale. Numerous studies have shown the importance of websites with user forums for people seeking information related to health. Parents turn to some of these sites, colloquially referred to as "mommy blogs," to share concerns about children's health care, including vaccination. Although substantial work has considered the role of social media, particularly Twitter, in discussions of vaccination and other health care-related issues, there has been little work on describing the underlying structure of these discussions and the role of persuasive storytelling, particularly on sites with no limits on post length. Understanding the role of persuasive storytelling at Internet scale provides useful insight into how people discuss vaccinations, including exemption-seeking behavior, which has been tied to a recent diminution of herd immunity in some communities. OBJECTIVE: To develop an automated and scalable machine-learning method for story aggregation on social media sites dedicated to discussions of parenting. We wanted to discover the aggregate narrative frameworks to which individuals, through their exchange of experiences and commentary, contribute over time in a particular topic domain. We also wanted to characterize temporal trends in these narrative frameworks on the sites over the study period. METHODS: To ensure that our data capture long-term discussions and not short-term reactions to recent events, we developed a dataset of 1.99 million posts contributed by 40,056 users and viewed 20.12 million times indexed from 2 parenting sites over a period of 105 months. Using probabilistic methods, we determined the topics of discussion on these parenting sites. We developed a generative statistical-mechanical narrative model to automatically extract the underlying stories and story fragments from millions of posts. We aggregated the stories into an overarching narrative framework graph. In our model, stories were represented as network graphs with actants as nodes and their various relationships as edges. We estimated the latent stories circulating on these sites by modeling the posts as a sampling of the hidden narrative framework graph. Temporal trends were examined based on monthly user-poststatistics. RESULTS: We discovered that discussions of exemption from vaccination requirements are highly represented. We found a strong narrative framework related to exemption seeking and a culture of distrust of government and medical institutions. Various posts reinforced part of the narrative framework graph in which parents, medical professionals, and religious institutions emerged as key nodes, and exemption seeking emerged as an important edge. In the aggregate story, parents used religion or belief to acquire exemptions to protect their children from vaccines that are required by schools or government institutions, but (allegedly) cause adverse reactions such as autism, pain, compromised immunity, and even death. Although parents joined and left the discussion forums over time, discussions and stories about exemptions were persistent and robust to these membership changes. CONCLUSIONS: Analyzing parent forums about health care using an automated analytic approach, such as the one presented here, allows the detection of widespread narrative frameworks that structure and inform discussions. In most vaccination stories from the sites we analyzed, it is taken for granted that vaccines and not vaccine preventable diseases (VPDs) pose a threat to children. Because vaccines are seen as a threat, parents focus on sharing successful strategies for avoiding them, with exemption being the foremost among these strategies. When new parents join such sites, they may be exposed to this endemic narrative framework in the threads they read and to which they contribute, which may influence their health care decision making.

18.
J Assoc Inf Sci Technol ; 66(9): 1847-1856, 2015 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-26478903

RESUMEN

We analyze access statistics of 150 blog entries and news articles for periods of up to 3 years. Access rate falls as an inverse power of time passed since publication. The power law holds for periods of up to 1,000 days. The exponents are different for different blogs and are distributed between 0.6 and 3.2. We argue that the decay of attention to a web article is caused by the link to it first dropping down the list of links on the website's front page and then disappearing from the front page and its subsequent movement further into background. The other proposed explanations that use a decaying with time novelty factor, or some intricate theory of human dynamics, cannot explain all of the experimental observations.

19.
Phys Rev Lett ; 106(17): 176801, 2011 Apr 29.
Artículo en Inglés | MEDLINE | ID: mdl-21635055

RESUMEN

The error rate in complementary transistor circuits is suppressed exponentially in electron number, arising from an intrinsic physical implementation of fault-tolerant error correction. Contrariwise, explicit assembly of gates into the most efficient known fault-tolerant architecture is characterized by a subexponential suppression of error rate with electron number, and incurs significant overhead in wiring and complexity. We conclude that it is more efficient to prevent logical errors with physical fault tolerance than to correct logical errors with fault-tolerant architecture.

20.
Nat Comput ; 9(2): 329-345, 2010 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-21475662

RESUMEN

In ensemble (or bulk) quantum computation, all computations are performed on an ensemble of computers rather than on a single computer. Measurements of qubits in an individual computer cannot be performed; instead, only expectation values (over the complete ensemble of computers) can be measured. As a result of this limitation on the model of computation, many algorithms cannot be processed directly on such computers, and must be modified, as the common strategy of delaying the measurements usually does not resolve this ensemble-measurement problem. Here we present several new strategies for resolving this problem. Based on these strategies we provide new versions of some of the most important quantum algorithms, versions that are suitable for implementing on ensemble quantum computers, e.g., on liquid NMR quantum computers. These algorithms are Shor's factorization algorithm, Grover's search algorithm (with several marked items), and an algorithm for quantum fault-tolerant computation. The first two algorithms are simply modified using a randomizing and a sorting strategies. For the last algorithm, we develop a classical-quantum hybrid strategy for removing measurements. We use it to present a novel quantum fault-tolerant scheme. More explicitly, we present schemes for fault-tolerant measurement-free implementation of Toffoli and σ(z)(») as these operations cannot be implemented "bitwise", and their standard fault-tolerant implementations require measurement.

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