Misperception of body verticality in neurological disorders: A systematic review and meta-analysis.

INTRODUCTION: The internal representation of verticality could be disturbed when a lesion in the central nervous system (CNS) affects the centers where information from the vestibular, visual, and/or somatosensory systems, increasing the risk of falling. OBJECTIVE: The aim was to evaluate the vestibular and somatosensory contribution to the verticality pattern in patients with stroke and other neurological disorders. METHODS: A literature search was performed in PubMed, Scopus, Web of Science, and CINAHL databases. Cross-sectional, case-control, and cohort studies comparing body verticality in patients with stroke or CNS diseases (CNSD) versus healthy controls were selected. Subjective postural vertical (SPV) in roll and pitch planes was used as the primary variable. RESULTS: Ten studies reporting data from 390 subjects were included. The overall effect for CNSD patients showed a misperception of body verticality in roll (standardized mean difference [SMD] = 1.05; 95% confidence interval [CI] .84-1.25) and pitch planes (SMD = 1.03; 95% CI .51-1.55). In subgroup analyses, a high effect was observed in the perception of SPV both in roll and pitch planes in stroke (p = .002) and other CNSD (p < .001). CONCLUSION: These findings suggest a potential misperception of SPV in patients with stroke and other neurological disturbances. Patients with CNSD could present an alteration of vestibular and somatosensory contribution to verticality construction, particularly stroke patients with pusher syndrome (PS), followed by those with PS combined with hemineglect.

Effectiveness of Dry Needling versus Manual Therapy in Myofascial Temporomandibular Disorders: A Single-Blind Randomized Controlled Trial.

Dry needling (DN) is an invasive physiotherapy technique employed for reducing myofascial pain. To compare the effectiveness of dry needling (DN) versus manual therapy (MT) in improving pain, active maximal mouth opening (AMMO) and cervical disability in patients with myofascial pain from temporomandibular disorders (TMDs) were investigated against these treatments. A single-blind, randomized controlled trial was carried out. Individuals (n = 50) with TMDs were randomly allocated in a 1:1 ratio to the DN (n = 25) or MT group (n = 25). Each group received three sessions, separated by 4 days, of either DN or MT. Outcomes were assessed according to pain intensity (Numeric Pain Rating Scale), AMMO (cm), disability (Neck Disability Index), and pressure-pain threshold (PPT) (digital algometry) from the active myofascial trigger points. In both groups, pain and neck disability were significantly lower at the end of treatment compared with those measured at baseline (pain: -2.52 with 95% CI: -3.43 to -1.60 for DN group; pain: -2.92 with 95% CI: -3.77 to -2.07 for MT group; disability: -3.2 with 95% CI: -4.31 to -2.09 for DN group; disability: -2.68 with 95% CI: -3.56 to -1.79 for MT group), but not were not lower after the first session, without differences between the groups. AMMO was significantly higher after the first session (0.16 with 95% CI: 0.03 to 0.29 for DN group; 0.30 with 95% CI: 0.20 to 0.41 for MT group) and at the end of treatment in both groups (0.27 with 95% CI: 0.14 to 0.41 for DN group; 0.37 with 95% CI: 0.22 to 0.52 for MT group) compared with the baseline measurements. Finally, PPT results for the masseter and pterygoid muscles were significantly higher at the end of treatment in both groups (without statistically significant differences between groups), but not after the first session. The assessed therapies, DN and MT, are equally effective in improving pain, AMMO, cervical disability, and PPT in the muscles directly involved in the temporomandibular joint biomechanics of patients with myofascial TMDs.

Optimal dose and type of exercise to reduce pain, anxiety and increase quality of life in patients with fibromyalgia. A systematic review with meta-analysis.

The aim of our meta-analysis was to compile the available evidence to evaluate the effect of physical exercise-based therapy (PEBT) on pain, impact of the disease, quality of life (QoL) and anxiety in patients with fibromyalgia syndrome (FMS), to determine the effect of different modes of physical exercise-based therapy, and the most effective dose of physical exercise-based therapy for improving each outcome. A systematic review and meta-analysis was carried out. The PubMed (MEDLINE), SCOPUS, Web of Science, CINAHL Complete and Physiotherapy Evidence Database (PEDro) databases were searched up to November 2022. Randomized controlled trials (RCTs) comparing the effects of physical exercise-based therapy and other treatments on pain, the impact of the disease, QoL and/or anxiety in patients with FMS were included. The standardized mean difference (SMD) and a 95% CI were estimated for all the outcome measures using random effect models. Three reviewers independently extracted data and assessed the risk of bias using the PEDro scale. Sixty-eight RCTs involving 5,474 participants were included. Selection, detection and performance biases were the most identified. In comparison to other therapies, at immediate assessment, physical exercise-based therapy was effective at improving pain [SMD-0.62 (95%CI, -0.78 to -0.46)], the impact of the disease [SMD-0.52 (95%CI, -0.67 to -0.36)], the physical [SMD 0.51 (95%CI, 0.33 to 0.69)] and mental dimensions of QoL [SMD 0.48 (95%CI, 0.29 to 0.67)], and the anxiety [SMD-0.36 (95%CI, -0.49 to -0.25)]. The most effective dose of physical exercise-based therapy for reducing pain was 21-40 sessions [SMD-0.83 (95%CI, 1.1--0.56)], 3 sessions/week [SMD-0.82 (95%CI, -1.2--0.48)] and 61-90 min per session [SMD-1.08 (95%CI, -1.55--0.62)]. The effect of PEBT on pain reduction was maintained up to 12 weeks [SMD-0.74 (95%CI, -1.03--0.45)]. Among patients with FMS, PEBT (including circuit-based exercises or exercise movement techniques) is effective at reducing pain, the impact of the disease and anxiety as well as increasing QoL. Systematic Review Registration: PROSPERO https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42021232013.

Magnesium in Kidney Function and Disease-Implications for Aging and Sex-A Narrative Review.

Magnesium (Mg) has a vital role in the human body, and the kidney is a key organ in the metabolism and excretion of this cation. The objective of this work is to compile the available evidence regarding the role that Mg plays in health and disease, with a special focus on the elderly population with chronic kidney disease (CKD) and the eventual sex differences. A narrative review was carried out by executing an exhaustive search in the PubMed, Scopus, and Cochrane databases. Ten studies were found in which the role of Mg and sex was evaluated in elderly patients with CKD in the last 10 years (2012-2022). The progression of CKD leads to alterations in mineral metabolism, which worsen as the disease progresses. Mg can be used as a coadjuvant in the treatment of CKD patients to improve glomerular filtration, but its use in clinical applications needs to be further characterized. In conclusion, there's a need for well-designed prospective clinical trials to advise and standardize Mg supplementation in daily clinical practice, taking age and sex into consideration.

Study Based on Gamification of Tests through Kahoot!™ and Reward Game Cards as an Innovative Tool in Physiotherapy Students: A Preliminary Study.

BACKGROUND: Kahoot! is an educational tool allowing teachers to create a series of gamified tests with the aim of reinforcing educational content, thus improving the teaching-learning process. The objective of this project is to evaluate the acquisition of content through gamified tests with Kahoot! and reward cards compared to the traditional teaching methodology (contents not reinforced). METHODS: This Physiotherapy Teaching Innovation Project (PTIP) was carried out in four subjects of the Degree in Physiotherapy at the University of Jaén (Spain). The teachers responsible for each subject were instructed in the use of Kahoot! and reward cards. These teachers randomly selected the contents that were going to be reinforced with Kahoot! while the other 50% of the contents would not be reinforced. In the final exam of each subject, the results related to the reinforced contents were compared with those non-reinforced and the degree of satisfaction of the students with the experience was evaluated. RESULTS: A total of 313 students participated in this PTIP. In all subjects, we determined a significant increase in the number of correct answers in an improvement range from 7% (95% CI 3.85 to 9.38) to more than 20% (95% CI 17.61 to 26.86) in favor of the questions that alluded to reinforced content using Kahoot! compared to the non-reinforced contents. More than 90% of the participants considered the use of Kahoot! useful and motivating. Our findings showed that Kahoot! motivated more than 65% of students to study daily. CONCLUSIONS: The students obtained better academic results in the questions related to contents reinforced with tests through Kahoot! and reward cards compared to those non-reinforced, showing that this methodology can be an effective tool to promote retention and content assimilation.

Commitment, perception and evidence-based practice training in Spanish nursing students: A multicentre cross-sectional study.

AIMS AND OBJECTIVES: To evaluate the commitment and level of self-perceived training in evidence-based practice among students of the Nursing degree of five Spanish universities. BACKGROUND: In university Health Sciences degrees, evidence-based clinical practice can directly or indirectly impact the quality of care, the cost of the service provided and the safety of clinical practice. DESIGN: Multicentre cross-sectional observational study according to STROBE guidelines. METHODS: The evidence-based skills in Practice questionnaire (CACH-PBE, for its acronym in Spanish) and the Utrecht Work Engagement Student Scale (UWES-9S) were used. The study was performed in five Spanish universities (Alicante, Castilla La Mancha, Jaen, Huelva and Seville) from October to December 2020, with 755 participants (Nursing students). RESULTS: A total mean score of 91.9 points (SD = 11.81) was observed for the CACH-PBE questionnaire and of 36.8 points (SD = 8.48 points) for the UWES-9S. In addition, the multivariate analysis predicted that variables such as sex, academia, university, intention to do a Master or Doctorate degree, the level of work engagement, and the previous training in evidence-based clinical practice were associated with a greater perception of evidence-based practice. CONCLUSION: The sample of Nursing degree students has intermediate-high levels of knowledge, skills and attitudes regarding evidence-based practice and work commitment, with differences observed between each of the universities. RELEVANCE TO CLINICAL PRACTICE: Nursing students should develop from intermediate to high levels of knowledge, skills and attitudes regarding evidence-based practice and work commitment. There are various actions to promote EBP, such as the incorporation of a specific course covering the subject into the nursing curriculum, and the selection, for clinical practices, of care units that implemented evidence-based care.

Post-transplant diabetes mellitus and renal cell cancer after renal transplantation.

BACKGROUND: Diabetes is a risk factor for cancer in the general population. However, few data are available on the association between post-transplant diabetes mellitus (PTDM) and cancer after transplantation. METHODS: We analyzed this issue in a Spanish cohort of patients without diabetes before transplantation. PTDM was diagnosed with consensus criteria at 12 months after transplantation and 12 months before the diagnosis of cancer. The association between PTDM and cancer (overall and specific types) was evaluated with regression analysis. RESULTS: During a follow-up of 12 years (interquartile range 8-14), 85 cases of 603 developed cancer (829/100 000/year) and 164 (27%) PTDM. The most frequent cancers were renal cell cancer (RCC) n = 15, 146/cases/100 000/year), lung (n = 12, 117/cases/100 000/year), colon (n = 9, 88/cases/100 000/year) and prostate (n = 9, 88/cases/100 000/year). In logistic regression, PTDM was not associated with cancer. Eight of the 164 patients with PTDM (4.9%) vs 7 of the 439 without PTDM developed RCC (1.6%) (P = .027). In multivariate analysis, PTDM was independently associated with RCC [odds ratio (OR) 2.92, confidence interval (CI) 1.03-8.27], adjusting for smoking (OR 4.020, 95% CI 1.34-12.02) and other covariates. PTDM was not associated with other types of cancer. CONCLUSIONS: Patients with PTDM must be considered a population at risk for RCC and accordingly, the subject of active surveillance.

Digital and Interactive Health Interventions Minimize the Physical and Psychological Impact of Breast Cancer, Increasing Women's Quality of Life: A Systematic Review and Meta-Analysis.

Digital and interactive health interventions (DIHIs), such as virtual-reality-based therapy (VRBT) and smartphone-app-based therapy (SABT), may be useful for reducing the impact of the signs and symptoms of breast cancer (BC) in women. The aim of this meta-analysis was to explore the effect of DIHIs on improving pain, anxiety, depression, quality of life (QoL), and upper extremity (UE) disability-related lymphedema in women with BC. METHODS: We searched PubMed Medline, Web of Science, Scopus, CINAHL, Physiotherapy Evidence Database, and SciELO for the period ending February 2022. We included studies that assessed the effect of DIHIs on UE motor disability, pain, anxiety, depression, and QoL in women with BC. The effect size was calculated using Cohen's standardized mean difference (SMD) and its 95% confidence interval (95% CI). RESULTS: Twenty studies providing data from 1613 women with BC were included. With respect to UE disability, DIHIs increased flexion (SMD, 1.92; 95%CI: -1.16, 2.68), abduction (SMD, 1.66; 95%CI: 0.91, 2.42), external rotation shoulder range of motion (SMD, 1.1; 95%CI: 0.36, 1.85), UE function (SMD, -0.72; 95%CI: -1.31, -0.13), and handgrip strength (SMD, 0.4; 95%CI: 0.21, 0.59). DIHIs reduced pain (SMD, -0.8; 95%CI: -1.31, -0.26), anxiety (SMD, -1.02; 95%CI: -1.71, -0.34), and depression (SMD, -1.57; 95%CI: -3.1, -0.08). Finally, DIHIs increased overall health (SMD, 0.6; 95%CI: 0.31, 0.89). CONCLUSIONS: Right at the end of therapy, DIHIs are effective at improving UE function, pain, anxiety, depression, and QoL in women with BC. VRBT has a greater effect than SABT for the assessed outcomes.

Understanding the adipose tissue acetylome in obesity and insulin resistance.

Obesity is a widely prevalent pathology with a high exponential growth worldwide. Altered lipid accumulation by adipose tissue is one of the main causes of obesity and exploring lipid homeostasis in this tissue may represent a source for the identification of possible therapeutic targets. The study of the proteome and the post-translational modifications of proteins, specifically acetylation due to its involvement in energy metabolism, may be of great interest to understand the molecular mechanisms involved in adipose tissue dysfunction in obesity. The objective of this study was to characterize the subcutaneous and omental adipose tissue acetylome in conditions of obesity and insulin resistance and to describe the importance of acetylation of key molecules in adipose tissue to use them as therapeutic targets. The results describe for the first time the acetylome of subcutaneous and omental adipose tissue under physiological and physiopathological conditions such as obesity and insulin resistance. New evidence showed different acetylation patterns between two main depots and highlight the molecular complexity of adipose tissue. Results showed changes in FABP4 acetylation in subcutaneous fat in relation to insulin resistance, thus unveiling a potential marker of depot-specific dysfunctional expansion in obesity-associated metabolic disease. Furthermore, it is shown that the acetylation of FABP4 affects its function, modulating the capacity of differentiation in adipocytes. In conclusion, this study demonstrates a profound, depot-specific alteration of adipose tissue acetylome, wherein the acetylation of FABP4 may play a key role in adipocyte differentiation and lipid accumulation.

Vibration or Transcutaneous Tibial Nerve Stimulation as a Treatment for Sexual Dysfunction in Women with Spinal Cord Injury: Study Protocol for a Randomized Clinical Trial.

BACKGROUND: Women with spinal cord injuries usually suffer from sexual dysfunction, such as alterations during arousal and an increase in the time to reach orgasm. However, little evidence has been found on its physiotherapeutic approach, as well as poor adherence to the latter. The aim of this study is to determine the effectiveness of two interventions to improve sexual dysfunction: the application of genital vibration and transcutaneous tibial nerve stimulation. METHODS: This is a randomized clinical trial that will recruit 54 women who, one year after a spinal cord injury, suffer from sexual dysfunction associated with the latter. The participants will be randomized to three groups: (a) intervention group 1 treated with transcutaneous tibial nerve electrostimulation (n = 18), (b) intervention group 2 treated with genital vibration (n = 18), and (c) a control group (n = 18). The treatment time will be 12 weeks. Adherence to the treatment will be evaluated, as well as the effectiveness of the treatment, through the Female Sexual Function Index, the Sexual Quality of Life-Female questionnaire, quantitative sensory tests, and the improvement reported by the patient in terms of arousal and orgasm. The evaluations will be carried out before the treatment, at the end of the treatment and 3, 6 and 12 months after the end of the treatment.

[Functional dependence and support for the older persons in Mexico, 2001-2026Dependência funcional e apoio em idosos no México, 2001-2026]. / Dependencia funcional y apoyo para personas mayores de México, 2001-2026.

OBJECTIVES: Identify the factors associated with future functional dependence in the elderly in Mexico and with receiving or not receiving support for basic activities of daily living (ADLs); and project the prevalence of functional dependence in 2026. METHODS: Data from the 2001 National Health and Aging Study (ENASEM) and from the 2012 and 2015 follow-up rounds were used. A multinomial logistic regression model was used to analyze factors associated with future dependence, and a logistic regression model was used for factors associated with receiving or not support. The projected number of older persons with functional dependence in 2026 was based on data from the 2015 ENASEM and on estimated rates from the model of future dependence. RESULTS: Older people, those with a lower educational level, those with hypertension, arthritis, or diabetes, those who had suffered a stroke or fall, and those with some degree of prior functional dependence had a significantly higher risk of mild or severe dependence and death within 11 years, compared to the reference group. Older people and those with severe dependence had higher odds of receiving support compared to reference groups. By 2026, it is estimated that 18.9% of older people in Mexico will have mild dependence and 9.3% will be severely dependent. CONCLUSIONS: Factors associated with future dependence and death were age, educational level, certain chronic diseases, having fallen, and having prior functional dependence; the factors associated with receiving support for basic ADLs were severe dependence and age. It is estimated that the prevalence of dependence will increase 2.1 times over 25 years (2001-2026).

OBJETIVOS: Identificar os fatores associados à dependência funcional futura e a receber apoio para a realização das atividades básicas da vida diária (ABVD) em pessoas idosas e fazer uma projeção da dependência funcional nesta população no México em 2026. MÉTODOS: Analisaram-se dados obtidos no Estudo Nacional de Saúde e Envelhecimento do México (ENASEM) de 2001 e em rodadas subsequentes da pesquisa de 2012 e 2015. Utilizou-se um modelo de regressão logística multinomial para analisar os fatores associados à dependência funcional futura da pessoa idosa e um outro modelo de regressão logística para analisar os fatores associados a receber apoio. As projeções para 2026 de idosos em situação de dependência foram feitas com base nos dados do ENASEM de 2015 e nas estimativas do modelo de dependência futura. RESULTADOS: Idade avançada, nível de escolaridade mais baixo, ter hipertensão, artrite, diabetes, história de embolia cerebral ou quedas e possuir algum grau de dependência funcional anterior foram os fatores que se associaram a um risco significativamente maior de dependência funcional (leve ou grave) e morte nos 11 anos seguintes em comparação aos grupos de referência. Idosos com idade avançada ou dependência grave apresentaram uma maior probabilidade de receber apoio para a realização das ABVD em comparação aos grupos de referência. A projeção para 2026 no México é que 18,9% das pessoas idosas terão dependência leve e 9,3% dependência grave. CONCLUSÕES: Os fatores associados a dependência funcional futura e morte foram idade, nível de escolaridade, certas doenças crônicas, história de quedas e dependência funcional anterior. Ter idade avançada e dependência grave severa foram os fatores associados a receber apoio para a realização das ABVD. Estima-se que a prevalência de dependência funcional em pessoas idosas aumentará 2,1 vezes em 25 anos (2001-2026).

Dependencia funcional y apoyo para personas mayores de México, 2001-2026

[RESUMEN]. Objetivos. Identificar los factores asociados con la dependencia funcional futura de las personas mayores en México, así como con recibir o no apoyo para la realización de actividades básicas de la vida diaria (ABVD), y proyectar la prevalencia de la dependencia funcional en 2026.Métodos. Se utilizaron los datos del Estudio Nacional de Salud y Envejecimiento (ENASEM) del 2001 y las rondas de seguimiento de 2012 y 2015. Se estimó un modelo de regresión logística multinomial para analizar los factores asociados con la dependencia futura y un modelo de regresión logística para los factores asociados con recibir o no apoyo. Para las proyecciones de personas mayores en situación de dependencia en 2026 se utilizaron los datos del ENASEM del 2015 y los coeficientes estimados del modelo de dependencia futura.Resultados. Las personas de más edad, las que tenían un nivel de educación más bajo, las que padecían de hipertensión, artritis, diabetes, las que habían sufrido una embolia cerebral o alguna caída, y las que tenían algún nivel de dependencia funcional previa presentaron un riesgo significativamente mayor de dependencia (leve o severa) y de fallecer en los 11 años siguientes respecto a sus referencias. Las personas de mayor edad o con dependencia severa tuvieron mayores probabilidades de recibir apoyo respecto a sus referen-cias. Para el año 2026, se estima que el 18,9% de las personas mayores en México tendrá dependencia leve y el 9,3% dependencia severa.Conclusiones. Los factores asociados con la dependencia futura y con fallecer fueron la edad, el nivel educacional, algunas enfermedades crónicas, haberse caído y tener dependencia funcional previa; los factores asociados con recibir apoyo para la realización de ABVD fueron tener dependencia severa y la edad. Se estima que la prevalencia de la dependencia aumentará 2,1 veces en 25 años (2001-2026).

[ABSTRACT]. Objectives. Identify the factors associated with future functional dependence in the elderly in Mexico and with receiving or not receiving support for basic activities of daily living (ADLs); and project the prevalence of functional dependence in 2026.Methods. Data from the 2001 National Health and Aging Study (ENASEM) and from the 2012 and 2015 follow-up rounds were used. A multinomial logistic regression model was used to analyze factors associated with future dependence, and a logistic regression model was used for factors associated with receiving or not support. The projected number of older persons with functional dependence in 2026 was based on data from the 2015 ENASEM and on estimated rates from the model of future dependence.Results. Older people, those with a lower educational level, those with hypertension, arthritis, or diabetes, those who had suffered a stroke or fall, and those with some degree of prior functional dependence had a significantly higher risk of mild or severe dependence and death within 11 years, compared to the reference group. Older people and those with severe dependence had higher odds of receiving support compared to reference groups. By 2026, it is estimated that 18.9% of older people in Mexico will have mild dependence and 9.3% will be severely dependent.Conclusions. Factors associated with future dependence and death were age, educational level, certain chronic diseases, having fallen, and having prior functional dependence; the factors associated with receiving support for basic ADLs were severe dependence and age. It is estimated that the prevalence of dependence will increase 2.1 times over 25 years (2001-2026).

[RESUMO]. Objetivos. Identificar os fatores associados à dependência funcional futura e a receber apoio para a reali-zação das atividades básicas da vida diária (ABVD) em pessoas idosas e fazer uma projeção da dependência funcional nesta população no México em 2026.Métodos. Analisaram-se dados obtidos no Estudo Nacional de Saúde e Envelhecimento do México (ENASEM) de 2001 e em rodadas subsequentes da pesquisa de 2012 e 2015. Utilizou-se um modelo de regressão logís-tica multinomial para analisar os fatores associados à dependência funcional futura da pessoa idosa e um outro modelo de regressão logística para analisar os fatores associados a receber apoio. As projeções para 2026 de idosos em situação de dependência foram feitas com base nos dados do ENASEM de 2015 e nas estimativas do modelo de dependência futura.Resultados. Idade avançada, nível de escolaridade mais baixo, ter hipertensão, artrite, diabetes, história de embolia cerebral ou quedas e possuir algum grau de dependência funcional anterior foram os fatores que se associaram a um risco significativamente maior de dependência funcional (leve ou grave) e morte nos 11 anos seguintes em comparação aos grupos de referência. Idosos com idade avançada ou dependência grave apresentaram uma maior probabilidade de receber apoio para a realização das ABVD em comparação aos grupos de referência. A projeção para 2026 no México é que 18,9% das pessoas idosas terão dependên-cia leve e 9,3% dependência grave.Conclusões. Os fatores associados a dependência funcional futura e morte foram idade, nível de escolari-dade, certas doenças crônicas, história de quedas e dependência funcional anterior. Ter idade avançada e dependência grave severa foram os fatores associados a receber apoio para a realização das ABVD. Esti-ma-se que a prevalência de dependência funcional em pessoas idosas aumentará 2,1 vezes em 25 anos (2001-2026).

Alteration of Postural Balance in Patients with Fibromyalgia Syndrome-A Systematic Review and Meta-Analysis.

Balance problems are one of the most frequent symptoms in patients with Fibromyalgia Syndrome (FMS). However, the extent and nature of this balance disorder are not known. The objective of this work was to determine the best evidence for the alteration of postural balance in patients with FMS and analyze differences with healthy controls. To meet this objective, a systematic review with meta-analysis was performed. A bibliographical search was carried out in PubMed Medline, Scopus, Web of Science, CINAHL and SciELO. Observational studies that assessed postural balance in patients with FMS compared to healthy subjects in baseline conditions, were selected. In a random-effect model, the pooled effect was calculated with the Standardized Mean Difference (SMD) and its 95% confidence interval (CI). Nineteen studies reporting data of 2347 participants (95% female) were included. FMS patients showed poor balance with a large effect on static (SMD = 1.578; 95% CI = 1.164, 1.992), dynamic (SMD = 0.946; 95% CI = 0.598, 1.294), functional balance (SMD = 1.138; 95% CI = 0.689, 1.588) and on balance confidence (SMD = 1.194; 95% CI = 0.914, 1.473). Analysis of the Sensory Organization Test showed large alteration of vestibular (SMD = 1.631; 95% CI = 0.467, 2.795) and visual scores (SMD = 1.317; 95% CI = 0.153, 2.481) compared to healthy controls. Patients with FMS showed worse scores for different measures of postural balance compared to healthy controls. Concretely, FMS patients appear to have poor vestibular and visual scores with a possible somatosensory dependence.

Nursing interfaces in rural care: an integrative review / Interfaces de enfermería en la atención rural: una revisión integradora / Interfaces da enfermagem no cuidado rural: revisão integrativa

ABSTRACT Objective: to know the issues in evidence in rural nursing. Method: a six-stage integrative review. Data was collected from May to July 2017, in the SciELO, CUIDEN, PubMed, and ScienceDirect databases, with "Rural nursing" as descriptor. The analysis used was qualitative with the construction of subsets and topics. Results: of the 30 articles analyzed, 32% addressed professional training; 25% collective health-related practices; 12% hospital care; 10% job satisfaction; 7% were dedicated to telehealth and 3% of the studies addressed the following topics: nurses' recruitment and permanence in rural areas, continuing education, and professional practice in urgency and emergency regulation centers. Conclusion: working in rural areas demands that nurses face particularities such as isolation, difficulty of access, diverse socioeconomic conditions and specific epidemiological profiles, which influence the professional practice, making it a challenge.

RESUMEN Objetivo: conocer los temas en evidencia en la enfermería en el territorio rural. Método: revisión integradora compuesta por seis etapas. Los datos se recolectaron de mayo a junio de2017 en las bases de datos SciELO, CUIDEN, PubMed y ScienceDirect, con el siguiente descriptor: "Rural nursing". El análisis empleado fue el cualitativo con la elaboración de subconjuntos y temas. Resultados: de los 30 artículos analizados, el 32% abordaron la formación profesional; el 25%, acciones relacionadas con la salud colectiva; el 12%, la atención hospitalaria; el 10%, la satisfacción en el trabajo; el 7% estaban dedicados a la telesalud y el 3% de los estudios trataron dos temas: reclutamiento y permanencia de las enfermeras en el Espacio rural, educación permanente y desempeño profesional en la central de regulación de urgencias y emergencias. Conclusión: para desempeñarse profesionalmente en el territorio rural, una enfermera debe hacer frente a diversas particularidades como el aislamiento, la dificultad de acceso, condiciones socioeconómicas diversas y perfiles epidemiológicos específicos, que influyen sobre la práctica profesional, factores que la convierten en un desafío.

RESUMO Objetivo: conhecer os temas em evidência na enfermagem no território rural. Método: revisão integrativa composta por seis etapas. Os dados foram coletados no período de maio a julho de 2017, nas bases SciELO, CUIDEN, PubMed, ScienceDirect, com o descritor "Rural nursing". A análise utilizada foi qualitativa com a construção de subconjuntos e tópicos. Resultados: dos 30 artigos analisados 32% abordavam a formação profissional; 25% ações relacionadas a saúde coletiva; 12% assistência hospitalar; 10% a satisfação no trabalho; 7% dedicaram a telessaúde e 3% dos estudos trataram dos temas: recrutamento e permanência das Enfermeiras no Espaço rural, educação permanente e a atuação profissional em central de regulação de urgência e emergência. Conclusão: a atuação no território rural demanda à enfermeira enfrentar particularidades como isolamento, dificuldade de acesso, condições socioeconômicas diversas e perfis epidemiológicos específicos, que influenciam a prática profissional, o que a torna um desafio.

Level of Stigma among Spanish Nursing Students toward Mental Illness and Associated Factors: A Mixed-Methods Study.

Mental health problems have been identified by the World Health Organization as a global development priority. Negative attitudes toward mental health patients have been documented in multiple health professionals. The aim of this study was to determine the level of stigma and associated factors toward people with mental health problems among students doing their degree in nursing. An explanatory sequential mixed-methods approach. A cross-sectional descriptive observational study was carried out on a sample of 359 students doing their degree in nursing. Students had to be enrolled in any of the four years of study of the degree at the time the questionnaire was done. We explored the perception and experience of students doing their degree in nursing regarding the level of stigma, through in-depth interviews (n = 30). The mean overall Mental Health Stigma Scale (MHSS) score was 30.7 points (SD = 4.52); 29.5% (n = 106) scored low for stigma, 49.9% (n = 179) showed moderate stigma, and 20.6% (n = 74) scored high. The multivariate analysis showed that 4th-year students had an OR of 0.41 (CI95%: 0.20-0.84) for high/moderate stigma and that 3rd-year students had an OR of 0.49 for high/moderate stigma compared with 1st-year students. We also observed that students with family members with mental health problems had an OR of 2.05 (CI95%: 1.19-3.56) for high/moderate stigma compared with students who did not have family members with mental health problems. The following categories emerged: fear and lack of knowledge, breaking the silence, and integration into society. The levels of mental health stigma in our sample of nursing students were moderate. Stigma levels were lower in 3rd- and 4th-year students (i.e., after having received training in mental health), and in students with family members with mental health problems.

El primer contacto hospitalario a través del Servicio de Urgencias es un predictor independiente de supervivencia global y de supervivencia libre de enfermedad en pacientes con cáncer colorrectal / First hospital contact via the Emergency Department is an independent predictor of overall survival and disease-free survival in patients with colorectal cancer

Objeto: el objetivo del presente estudio es examinar la asociación entre el tipo de admisión hospitalaria, la supervivencia y las características patológicas de una amplia población de pacientes con cáncer colorrectal. Métodos: realizamos un estudio en 1.079 pacientes diagnosticados en el Hospital Costa del Sol de Marbella con cáncer colorrectal y evaluamos la relación entre su tasa de supervivencia y la vía por la que realizaron el primer contacto con el hospital (admisión programada o de urgencias). Las variables incluidas en nuestro estudio fueron las siguientes: edad, género, localización del tumor, estadio patológico, grado de diferenciación, quimioterapia previa a la cirugía y supervivencia. Resultados: los pacientes admitidos por primera vez al hospital a través del Servicio de Urgencias fueron diagnosticados con mayor frecuencia de cáncer de colon (63,7%) y con tumores pobremente diferenciados (64,2%) y metastásicos (70%). En el análisis de regresión de Cox la supervivencia libre de enfermedad produjo una razón de riesgo (RR) de 1,36 (intervalo de confianza [IC] 95%: 1,11-1,66) para los pacientes del Servicio de Urgencias y para la supervivencia global de 1,41 (IC 95%: 1,14-1-76). Conclusiones: La admisión hospitalaria a través del Servicio de Urgencias es un indicador de agresividad y de peor pronóstico frente a los pacientes que ingresan por vía programada

Aims: the aim of this study was to examine the possible association between the type of hospital admission and subsequent survival of the patient, as well as the pathological features recorded in a large population of patients with colorectal cancer. Methods: the study included 1,079 patients diagnosed with colon or rectal cancer in the Hospital Costa del Sol (Marbella, Spain). The relationship between patient survival rate and type of first admission to the hospital (elective or emergency admission) was assessed. The following variables were studied: age, gender, tumor location, pathological stage, differentiation grade, chemotherapy before surgery and survival. Results: colon tumors are more common in patients admitted to hospital for the first time via the emergency service (63.7%) and the tumors tend to be poorly differentiated (64.2%) and metastatic (70%). These patients also present a more aggressive disease and a poorer prognosis than patients with an elective admission. With regard to patients from the Emergency Department, a Cox regression analysis showed a risk-ratio (RR) of 1.36 (confidence interval [CI] 95%: 1.11-1.66) for disease-free survival and of 1.41 (95% CI: 1.14-1.76) for overall survival. Conclusions: hospital admission via the Emergency Department is an indicator of aggressiveness and poorer prognosis compared to patients who enter via programmed routes

Professional Identity of Nurse Manager in the Light of the Structural Dialectic Care Model / Identidad profesional del enfermero gestor a la luz del Modelo Estructural Dialéctico de los Cuidados / Identidade profissional do enfermeiro gestor à luz do Modelo Estrutural Dialético dos Cuidados

ABSTRACT Objectives: To identify in the scientific literature the identity-related configurations inherent to the nurse's managerial practices of a professional that works in a hospital setting, and to analyze them in the light of the Structural Dialectic Care Model (SDCM). Materials and method: The article concerns about a qualitative research where an integrative review was made enabling the selection of 15 articles, analyzed in light of the SDCM. Results: From the 15 selected articles, three thematic axes were established: Leadership, care and conflicts. Conclusions: It was concluded that the SDCM has made it possible to discover the nurse's identity models as a managerial agent in the diverse pluralities articulated to the identity-related processes of such professional.

RESUMEN Objetivos: identificar en la literatura científica las configuraciones identitarias inherentes a las prácticas gerenciales del enfermero, que actúa en el entorno hospitalario, y analizarlas a la luz del Modelo Estructural Dialéctico de los Cuidados (MEDC). Materiales y método: investigación cualitativa en la que se realizó una revisión integradora que posibilitó seleccionar 15 artículos, analizados desde el MEDC. Resultados: a partir de los artículos seleccionados, se establecieron tres ejes temáticos: liderazgo, cuidado y conflictos. Conclusiones: el MEDC ha posibilitado averiguar los modelos identitarios del enfermero como agente gestor en las diversas pluralidades articuladas a los procesos identitarios de dicho profesional.

RESUMO Objetivos: identificar, na literatura científica, as configurações identitárias inerentes às práticas gerenciais do enfermeiro que atua em ambiente hospitalar e analisá-las à luz do Modelo Estrutural Dialético dos Cuidados (MEDC). Materiais e método: trata-se de uma pesquisa qualitativa. Foi realizada uma revisão integrativa que possibilitou selecionar 15 artigos, analisados à luz do MEDC. Resultados: a partir dos 15 artigos selecionados, foram estabelecidos três eixos temáticos: liderança, cuidado e conflitos. Conclusões: conclui-se que o MEDC possibilitou averiguar os modelos identitários do enfermeiro, como agente gestor, nas diversas pluralidades articuladas aos processos identitários desse profissional.