RESUMEN
El papiloma de células cilíndricas es el más raro de los tres tipos morfológicos de papilomas que pueden darse en la mucosa nasal o de senos paranasales. Presentamos el caso de una mujer afecta de una tumoración a nivel de seno maxilar dcho y fosa nasal dcha que fue resecada con el diagnóstico definitivo de papiloma schneideriano de células oncocíticas. Revisamos la literatura: hallazgos clínicos, tratamiento y evolución
Cylindrical cell papilloma is the rarest of three morphologically distinct papillomas that occur in the nose and paranasal sinuses. We report a case of a woman affected of a right sinonasal mass who was removed with the final histopatological diagnosis of oncocytic schneiderian papilloma. We review the literature clinical findings, treatment and evolution
Asunto(s)
Femenino , Anciano , Humanos , Papiloma/patología , Neoplasias Nasales/patología , Seno Maxilar/patología , Células Oxífilas/patología , Neoplasias de los Senos Paranasales/patologíaRESUMEN
The evaluation of spermatic morphology is of importance due to its prognostic value in potential male fertility, both in natural and in assisted reproduction. In the present work, the morphologic profile of samples of semen from normal and dispermic patients was determined, in order to establish a correlation between structure and function. Samples were obtained from male partners of infertile couples who attended andrologic consultation. The smears were stained by the Papanicolaou technique, and the criteria of the OMS and the recent modification of Kruger were followed to evaluate spermatic morphology. Of all the patients studied (n = 46), 35
were normospermics (A), 39
asthenospermics, 7
oligospermics, 2
terastospermics and 17
presented combined alterations. The average percentage of normal spermatozoa was of 23.7 +/- 1.23 in the whole population. When group A patients were compared with asthenospermics, significant differences were found in the percentage of spermatozoa with middle piece and tail alterations, in the last group (p < 0.02). Similarly, when samples were analysed according to the presence of alterations: none (A), one (B) two or more (C), it was observed that the percentage of normal forms decreased in the groups in that order (A < B < C); (A or B vs C p < 0.05). The percentage of tapering spermatozoa was significantly higher in group C (p < 0.01 vs A or B). From the above results, it appears that 1) the larger number of functional alterations is related to a higher percentage of structural anomalies, and 2) the deficient motility in the asthenospermic group, is associated to the middle piece and tail alterations.(ABSTRACT TRUNCATED AT 250 WORDS)
RESUMEN
The evaluation of spermatic morphology is of importance due to its prognostic value in potential male fertility, both in natural and in assisted reproduction. In the present work, the morphologic profile of samples of semen from normal and dispermic patients was determined, in order to establish a correlation between structure and function. Samples were obtained from male partners of infertile couples who attended andrologic consultation. The smears were stained by the Papanicolaou technique, and the criteria of the OMS and the recent modification of Kruger were followed to evaluate spermatic morphology. Of all the patients studied (n = 46), 35
were normospermics (A), 39
asthenospermics, 7
oligospermics, 2
terastospermics and 17
presented combined alterations. The average percentage of normal spermatozoa was of 23.7 +/- 1.23 in the whole population. When group A patients were compared with asthenospermics, significant differences were found in the percentage of spermatozoa with middle piece and tail alterations, in the last group (p < 0.02). Similarly, when samples were analysed according to the presence of alterations: none (A), one (B) two or more (C), it was observed that the percentage of normal forms decreased in the groups in that order (A < B < C); (A or B vs C p < 0.05). The percentage of tapering spermatozoa was significantly higher in group C (p < 0.01 vs A or B). From the above results, it appears that 1) the larger number of functional alterations is related to a higher percentage of structural anomalies, and 2) the deficient motility in the asthenospermic group, is associated to the middle piece and tail alterations.(ABSTRACT TRUNCATED AT 250 WORDS)
RESUMEN
Oxygen uptake and isometric developed tension (IDT) of isolated rat portal vein were simultaneously measured after glucose removal, following the readmission of metabolic substrates and addition of 2-deoxy-D-glucose (2-DG) or insulin. In control conditions, basal O2 uptake was 0.128 +/- 0.004 microliter O2/mg dry weight/min (n = 50). After 40 min of incubation in a glucose-free medium, IDT and O2 uptake decayed to a similar degree. Addition of 11 mM glucose, 5 mM pyruvate, acetate, lactate or butyrate to hypodynamic veins, elicited differential recoveries in the mechanical and metabolic parameters, pyruvate and acetate being the most effective. Insulin (0.1 U/ml) added 5 min prior to readmission of 11 mM glucose, increased the restoration of IDT without any effect on oxygen uptake. 2-DG 5.5 mM, when added in glucose-free medium, abolished IDT but only depressed the cellular respiration by 38
at 20 min; these effects were decreased in presence of glucose (11 mM). These results suggest that the oxygen uptake of this vessel depends, among other factors, on the exogenous substrate offered. They show also the relationship between peak of developed isometric force and metabolic activity as well as the relevance of glycolytic and oxidative pathways in this tissue.