1.
Bioorg Med Chem Lett
; 24(5): 1417-20, 2014 Mar 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-24485781
RESUMEN
A series of methoxynaphthalene amides were prepared and evaluated as alternatives to quinolizidinone amide M1 positive allosteric modulators. A methoxy group was optimal for M1 activity and addressed key P-gp issues present in the aforementioned quinolizidinone amide series.