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BMC Infect Dis ; 19(1): 75, 2019 Jan 21.
Artículo en Inglés | MEDLINE | ID: mdl-30665366

RESUMEN

BACKGROUND: Acute respiratory infections (ARIs) represent an important cause of morbidity and mortality in children, remaining a major public health concern, especially affecting children under 5 years old from low-income countries. Unfortunately, information regarding their epidemiology is still limited in Peru. METHODS: A secondary data analysis was performed from a previous cross-sectional study conducted in children with a probable diagnosis of Pertussis from January 2010 to July 2012. All samples were analyzed via Polymerase Chain Reaction (PCR) for the following etiologies: Influenza-A, Influenza-B, RSV-A, RSV-B, Adenovirus, Parainfluenza 1 virus, Parainfluenza 2 virus, Parainfluenza 3 virus, Mycoplasma pneumoniae and Chlamydia pneumoniae. RESULTS: A total of 288 patients were included. The most common pathogen isolated was Adenovirus (49%), followed by Bordetella pertussis (41%) from our previous investigation, the most prevelant microorganisms were Mycoplasma pneumonia (26%) and Influenza-B (19.8%). Coinfections were reported in 58% of samples and the most common association was found between B. pertussis and Adenovirus (12.2%). CONCLUSIONS: There was a high prevalence of Adenovirus, Mycoplasma pneumoniae and other etiologies in patients with a probable diagnosis of pertussis. Despite the presence of persistent cough lasting at least two weeks and other clinical characteristics highly suspicious of pertussis, secondary etiologies should be considered in children under 5 years-old in order to give a proper treatment.


Asunto(s)
Infecciones del Sistema Respiratorio/microbiología , Infecciones del Sistema Respiratorio/virología , Tos Ferina/etiología , Infecciones por Adenoviridae/epidemiología , Infecciones por Adenoviridae/etiología , Bordetella pertussis/genética , Bordetella pertussis/aislamiento & purificación , Preescolar , Infecciones por Chlamydophila/epidemiología , Infecciones por Chlamydophila/etiología , Chlamydophila pneumoniae/genética , Chlamydophila pneumoniae/aislamiento & purificación , Tos/microbiología , Estudios Transversales , Femenino , Hospitalización , Humanos , Lactante , Recién Nacido , Gripe Humana/epidemiología , Gripe Humana/etiología , Masculino , Mycoplasma pneumoniae/aislamiento & purificación , Virus de la Parainfluenza 3 Humana/genética , Virus de la Parainfluenza 3 Humana/aislamiento & purificación , Perú/epidemiología , Neumonía por Mycoplasma/epidemiología , Neumonía por Mycoplasma/microbiología , Infecciones del Sistema Respiratorio/epidemiología , Infecciones por Respirovirus/epidemiología , Infecciones por Respirovirus/etiología , Tos Ferina/diagnóstico , Tos Ferina/epidemiología
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