[A comparison of two modalities of complex chemoradiotherapy for locally advanced nasopharyngeal carcinoma]. / Sravnitel'naia otsenka variantov kompleksnogo lecheniia nedifferentsirovannogo mestnorasprostranennogo raka nocoglotki.

Two modalities of complex chemoradiotherapy for locally advanced nasopharyngeal carcinoma stage III-IV were compared in the treatment of 52 patients. Thirty-four patients (group I) received polychemotherapy: cisplatin--100 mg/sq.m, i.v., dropwise, on day 4, plus ACOP (adriamycin 35 mg/sq.m, i.v.--4; cyclophosphamide 750 mg/sq.m, i.v.--4, day 1; vincristine 1.4 mg/sq.m, i.v.--4, and prednisolone 100 mg/sq.m, per os, days 1-5; group II (18)--cisplatin 100 mg/sq.m, day 4, plus 5-FU 1,000 mg, i.v.--4, injection, days 1-3. Full response was registered in 93.7% (group I) and 93.3% (group II). Overall 5-year and relapse-free survival was 85 and 63% (group I), and 83 and 56% (group II), respectively. There were no significant differences in radiation-related injury incidence in both groups. The best results were reported with chemoradiotherapy using two courses: an induction one and an adjuvant cisplatin drugs treatment concurrent with ACOP or 5-FU.

[Computed tomography in pre-irradiation topometry applied to diseases of the thoracic organs]. / Komp'iuternaia tomografiia v predluchevoi topometrii pri zabolavaniiakh organov grudnoi kletki.

The authors describe methods of pre-irradiation topometry in patients with thoracic tumors. They are based on patients' examination using an X-ray simulator and a computerized tomograph. The superiority of these methods over the previously used conventional methods was shown. The authors presented 77 cases observed by them. Radiation therapy plans in 48% of the patients were changed as a result of pre-irradiation investigation.

[Dosimetric basis of mean fractionation in the irradiation of bone metastases in breast cancer]. / Dozimetricheskoe obosnovanie srednego fraktsionirovaniia pri obluchenii kostnykh metastazov raka molochnoi zhelezy.

Proceeding from the drawing of maps with biologically isoeffective percentage doses the authors provide a dosimetric substantiation of gamma-beam irradiation of different parts of the bony skeleton using the following irradiation scheme: a single dose of 4 Gy, 5-6 fractions daily. It has been shown that to choose a therapeutic plan in the utilization of a nonstandard scheme of fractionation, the calculation of the TDF factor by Orton's tables is safe and illustrative. By way of example are given maps of isoeffective doses used in the irradiation of bone metastases in breast cancer patients with metastases to different parts of the skeleton.

[Importance of thermography in the overall examination of oncological patients]. / Znachenie termografii v kompleksnom obsledovanii onkologicheskikh bol'nykh.

Possibilities of remote thermography for differential diganosis of malignant and bening tumours are described. It helps in more exact definition of tumours topography and distribution for better planning of their irradiation. Diagnostic accuracy at the combined thermographic and radioisotope investigations was proved on 153 women with mammary gland diseases and on 77 women with soft tissue damage. Some recommendations offered concern the improvement of thermovision apparatus.