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1.
Cancers (Basel) ; 15(14)2023 Jul 08.
Artículo en Inglés | MEDLINE | ID: mdl-37509201

RESUMEN

PURPOSE: To assess the role of preoperative CT-based skeletal muscle mass depletion on postoperative clinical outcomes and survival in patients who underwent total laryngectomy for cancer. METHODS: Patients operated on between January 2011 and March 2020 were retrospectively included. Skeletal muscle area and intra- and inter-muscular fat accumulation were measured at the third lumbar vertebral level on preoperative CT scans. Skeletal muscle mass depletion was defined based on pre-established cut-off values. Their association with postoperative morbidity, length of stay (LOS), costs, and survival was assessed. RESULTS: A total of 84 patients were included, of which 37 (44%) had preoperative skeletal muscle mass depletion. The rate of postoperative fistula (23% vs. 35%, p = 0.348), cutaneous cervical dehiscence (17% vs. 11%, p = 0.629), superficial incisional surgical site infections (SSI) (12% vs. 10%, p = 1.000), and unplanned reoperation (38% vs. 37%, p = 1.000) were comparable between the two patient groups. No difference in median LOS was observed (41 vs. 33 days, p = 0.295), nor in treatment costs (119,976 vs. 109,402 CHF, p = 0.585). The median overall survival was comparable between the two groups (3.43 vs. 4.95 years, p = 0.09). CONCLUSIONS: Skeletal muscle mass depletion alone had no significant impact on postoperative clinical outcomes or survival.

3.
J Oral Pathol Med ; 51(10): 888-896, 2022 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-35347777

RESUMEN

Vascular anomalies are rare lesions of diverse nature that may affect the head and neck region. Any mass in or around the upper airway has the potential to obstruct or compromise it. The absolute priority, before etiologic treatment, is the evaluation of the risk for the airway and its management. Prenatal diagnosis of an upper airway obstruction requires a planned delivery in a center having a specialized team experienced in managing a compromised feto-neonatal airway, and who could perform an ex-utero intrapartum treatment to secure the airway. Even after birth, the airway remains central in the patient's overall management. Signs and symptoms of airway compromise must be evaluated keeping in mind the specific requirements of infants and small children and being aware that rapid worsening may occur. The treatment is then tailored to the patient and his lesion with the goal of improving symptoms while avoiding treatment-related complications. Maintaining reasonable expectations by the patient and families are part of a successful management. Cure is achievable for small and localized lesions, but symptom relief and mitigation of functional, esthetic and psychological impairments is the goal for large and complex lesions. If a tracheotomy was required, decannulation is one of the primary management goals.


Asunto(s)
Obstrucción de las Vías Aéreas , Malformaciones Vasculares , Niño , Femenino , Humanos , Lactante , Recién Nacido , Embarazo , Obstrucción de las Vías Aéreas/etiología , Obstrucción de las Vías Aéreas/cirugía , Estética Dental , Laringoestenosis , Diagnóstico Prenatal/efectos adversos , Traqueotomía
4.
Ann Thorac Surg ; 113(5): e393-e395, 2022 05.
Artículo en Inglés | MEDLINE | ID: mdl-34474022

RESUMEN

Endoscopic management of benign or malignant airway obstructions sometimes requires stenting after dilatation or debulking of the tumor. Straight stents are highly prone to migration in the trachea and the main bronchus, with potential catastrophic consequences. Multiple fixation strategies have been described to secure subglottic stents, each having certain limitations. This report describes a novel, "inside-to-outside" stent fixation in the upper airway using the Lichtenberger needle carrier in 2 consecutive patients.


Asunto(s)
Obstrucción de las Vías Aéreas , Estenosis Traqueal , Obstrucción de las Vías Aéreas/cirugía , Bronquios , Humanos , Stents , Tráquea/cirugía , Estenosis Traqueal/cirugía
5.
J Craniofac Surg ; 32(7): 2297-2300, 2021 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-33840766

RESUMEN

ABSTRACT: Reconstructions after oncologic full-thickness rhinectomies are often deferred from the ablative surgery. Definitive silicone prostheses are usually not used for transitional rehabilitation, and therefore, patients may deal with major facial defects for a long time before reconstruction. The aim was to develop a time- and cost-effective digital workflow to three-dimensional print temporary nasal prostheses and to assess patients' satisfaction. This prospective study enrolled all consecutive patients after full thickness ablative surgery and deferred reconstruction, from May 2018 to October 2019, at a tertiary care academic institution. With a dedicated software, the pre- and postoperative scans were three-dimensional processed to create the prosthesis and they were directly printed in elastic transparent resin. A cross-sectional survey was conducted 4 months after the rehabilitation to assess patients' satisfaction regarding comfort, aesthetics, and security of the retaining system. Seven patients were enrolled and they were all rehabilitated using this workflow. Mean time of design was 2h48 (SD 40 minutes), and mean printing time was 5h18 (SD 1 hour). Mean cost of production was 753 U.S. Dollars (SD 144 U.S. Dollars). Median scores of the visual analog scales were 8 out of 10 for each topic with interquartile range of 4 to 7 for aesthetics, 7 to 9 for comfort, and 7 to 10 for security of the retaining system. It has shown its feasibility in terms of costs and time of production. Patients were satisfied and it can be considered as a mean to help patients to deal with treatment sequelaes before definitive reconstruction.


Asunto(s)
Implantes Dentales , Satisfacción del Paciente , Estudios Transversales , Estética Dental , Humanos , Impresión Tridimensional , Estudios Prospectivos , Prótesis e Implantes , Diseño de Prótesis , Flujo de Trabajo
6.
Rev Med Suisse ; 16(709): 1845-1848, 2020 Oct 07.
Artículo en Francés | MEDLINE | ID: mdl-33026725

RESUMEN

The surgical management of unilateral and bilateral vocal cord paralysis depends on the severity of the condition, the potential for spontaneous recovery, the patient's age and vocal expectations. Standardized re-innervation surgeries, unilateral non-selective and bilateral selective, are viable alternatives to static procedures currently under evaluation in prospective studies. Neurorraphy of the ansa cervicalis loop to the recurrent laryngeal nerve allows lasting vocal recovery and potentially superior results to medialization and thyroplasty, by maintaining the visco-elastic properties of the vocal cord and preventing its atrophy. Selective bilateral reinnervation shows potential for recovery of inspiratory abduction with improved respiratory function without vocal deterioration.


La prise en charge chirurgicale des paralysies cordales uni et bilatérales dépend de la sévérité de l'atteinte, du potentiel de récupération spontanée, de l'âge du patient et de ses attentes. De nouvelles stratégies standardisées de réinnervations, unilatérales non sélectives et bilatérales sélectives, sont désormais appliquées en clinique et en cours d'études prospectives. La neurorraphie de l'anse cervicale au nerf laryngé récurrent permet un rétablissement vocal durable et potentiellement supérieur aux techniques statiques de médialisation et thyroplastie, par maintien des propriétés viscoélastiques de la corde et prévention de sa fibrose. La réinnervation bilatérale sélective montre un potentiel de récupération de l'abduction inspiratoire avec une amélioration des fonctions respiratoires sans détérioration vocale.


Asunto(s)
Laringe/cirugía , Nervio Laríngeo Recurrente/cirugía , Parálisis de los Pliegues Vocales/cirugía , Pliegues Vocales/cirugía , Humanos , Estudios Prospectivos
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