Monitoring biosecurity in poultry production: an overview of databases reporting biosecurity compliance from seven European countries.

Compliance with required on-farm biosecurity practices reduces the risk of contamination and spread of zoonotic and economically important diseases. With repeating avian influenza epidemics in the poultry industry, the need to monitor and improve the overall level of biosecurity is increasing. In practice, biosecurity compliance is assessed by various actors (e.g., academic, private and public institutions), and the results of such assessments may be recorded and gathered in databases which are seldom shared or thoroughly analyzed. This study aimed to provide an inventory of databases related to the assessment of biosecurity in poultry farms in seven major poultry-producing European countries to highlight challenges and opportunities associated with biosecurity data collection, sharing, and use. The institutions in charge of these databases were contacted and interviewed using a structured questionnaire to gather information on the main characteristics of the databases and the context of their implementation. A total of 20 databases were identified, covering the gamut of poultry species and production types. Most databases were linked to veterinary health authorities or academia, and to a lesser extent interbranch organizations. Depending on the institutions in charge, the databases serve various purposes, from providing advice to enforcing regulations. The quality of the biosecurity data collected is believed to be quite reliable, as biosecurity is mostly assessed by trained farm advisors or official veterinarians and during a farm visit. Some of the databases are difficult to analyze and/or do not offer information concerning which biosecurity measures are most or least respected. Moreover, some key biosecurity practices are sometimes absent from certain databases. Although the databases serve a variety of purposes and cover different production types, each with specific biosecurity features, their analysis should help to improve the surveillance of biosecurity in the poultry sector and provide evidence on the benefits of biosecurity.

Effects of habitat fragmentation and hunting activities on African swine fever dynamics among wild boar populations.

African Swine Fever (ASF) has been slowly but steadily increasing its endemic range throughout Europe, posing an imminent risk to the pig industry. ASF transmission among wild boar occurs mainly through wild boar population movements, hence wild boar presence and density are important risk factors for introducing, maintaining, and spreading the disease. The understanding of wild boar population dynamics and their role in ASF transmission and persistence remains limited. It is crucial to gain knowledge in this area to improve wildlife management while minimizing the risks for ASF introduction and spread. We adapted an individual-based spatio-temporal stochastic model developed by Halasa et al. (2019) and tailored it to two regions in France. The model assessed yearly hunting activity, the carcass persistence seasonality, and the specific landscape characteristics of the Franco-Belgian border region and the Pyrénées-Atlantiques department. Following the establishment of local population dynamics through preliminary runs of the model, the model was run 100 iterations over 8 years in the two study areas where ASF was randomly seeded after the 2nd year of simulation. For each scenario, the model was initiated with 500 wild boar groups randomly spread across the study areas. Hunting activities were included and excluded to assess the impact on population growth and ASF spread. Results showed an ever-growing wild boar population for all scenarios, which was balanced when hunting activities were included. When introducing ASF, the wild boar populations were dramatically impacted in both areas with a decrease of 63 % of the population at the Franco-Belgian border and 86 % in the Pyrénées-Atlantiques department. Habitat fragmentation and landscape connectivity were highlighted as important factors shaping ASF propagation. The Franco-Belgian border, which had the most fragmented habitat with unsuitable areas for wild boars, was shown to limit wild boar movements, reducing the probability, and spread of ASF across the landscape. The lack of connectivity was reflected in a less effective transmission and lower number of infected groups (406 versus 467). In contrast, the epidemic duration was lengthened in the fragmented habitat compared to the homogenous area (2.6 years vs 1.6 years). This study provided information on defining and implementing control measures in case of an ASF incursion, since delimitation of the area via fences artificially induces landscape fragmentation, which is important for controlling ASF outbreaks.

Mechanistic modelling of African swine fever: A systematic review.

The spread of African swine fever (ASF) poses a grave threat to the global swine industry. Without an available vaccine, understanding transmission dynamics is essential for designing effective prevention, surveillance, and intervention strategies. These dynamics can often be unraveled through mechanistic modelling. To examine the assumptions on transmission and objectives of the mechanistic models of ASF, a systematic review of the scientific literature was conducted. Articles were examined across multiple epidemiological and model characteristics, with filiation between models determined through the creation of a neighbor-joined tree using phylogenetic software. Thirty-four articles qualified for inclusion, with four main modelling objectives identified: estimating transmission parameters (11 studies), assessing determinants of transmission (7), examining consequences of hypothetical outbreaks (5), assessing alternative control strategies (11). Population-based (17), metapopulation (5), and individual-based (12) model frameworks were represented, with population-based and metapopulation models predominantly used among domestic pigs, and individual-based models predominantly represented among wild boar. The majority of models (25) were parameterized to the genotype II isolates currently circulating in Europe and Asia. Estimated transmission parameters varied widely among ASFV strains, locations, and transmission scale. Similarly, parameter assumptions between models varied extensively. Uncertainties on epidemiological and ecological parameters were usually accounted for to assess the impact of parameter values on the modelled infection trajectory. To date, almost all models are host specific, being developed for either domestic pigs or wild boar despite the fact that spillover events between domestic pigs and wild boar are evidenced to play an important role in ASF outbreaks. Consequently, the development of more models incorporating such transmission routes is crucial. A variety of codified and hypothetical control strategies were compared however they were all a priori defined interventions. Future models, built to identify the optimal contributions across many control methods for achieving specific outcomes should provide more useful information for policy-makers. Further, control strategies were examined in competition with each other, which is opposed to how they would actually be synergistically implemented. While comparing strategies is beneficial for identifying a rank-order efficacy of control methods, this structure does not necessarily determine the most effective combination of all available strategies. In order for ASFV models to effectively support decision-making in controlling ASFV globally, these modelling limitations need to be addressed.