Impact of future scenarios of climate change on lignin dynamics in soil: A case study in a Mediterranean savannah.

Lignin is an abundant and recalcitrant biopolymer of major relevance as soil organic matter (SOM) component playing a significant role in its stabilization. In this work, a factorial field experiment was established, where three climatic treatments (W, warming; D, drought; W + D, warming + drought), mimicking future climate change scenarios were installed over five years in a Mediterranean savannah "dehesa", accounting for its landscape diversity (under the tree canopy and in open grassland). A combination of analytical pyrolysis (Py-GC/MS) and the study of biogeochemical proxies based on lignin monomers is used for the direct detection of lignin-derived phenols and to infer possible shifts in lignin dynamics in soil. A total of 27 main lignin-derived methoxyphenols were identified, exhibiting different patterns and proportions, mainly driven by the effect of habitat, hence biomass inputs to SOM. An accelerated decomposition of lignin moieties -(exhibited by higher LG/LS and Al/K + Ac ratios)- is particularly exacerbated by the effect of all climatic treatments. There is also an overall effect on increasing lignin oxidation of side chain in syringyl units, especially under the tree canopy due to the alteration in biomass degradation and potential stimulation of enzyme activities. Conversely, in open grassland these effects are slower since the microbial community is expected to be already adapted to harsher conditions. Our findings suggests that climate change-related temperature and soil moisture deviations impact soil lignin decomposition in dehesas threatening this productive Mediterranean agroecosystem and affecting the mechanism of soil carbon storage.

Guías y algoritmos clínicos de tratamiento de la depresión en atención primaria: ¿son todos iguales? / Evaluation of clinical guidelines and algorithms for treatment of depression in primary care: are they all the same?

Objetivo. La consulta por depresión ocupa el 40% de las consultas al médico de asistencia primaria. Se buscan maneras de reorganizar el proceso de atención a la depresión integrando herramientas como el uso de guías y algoritmos clínicos. Objetivo. Ante la diversidad de opciones es importante conocer una o dos herramientas para aplicarlas adecuadamente. El objetivo es analizar y comparar las guías de tratamiento de la depresión con mayor difusión que incluyan la consulta de atención primaria. Material y métodos. Se realiza una revisión de la bibliografía encontrada en PubMed y en publicaciones de Sociedades Científicas. Las guías se comparan aplicando el instrumento «Appraisal of Guidelines Research and Evaluation Colaboration» (AGREE). Resultados. Los algoritmos de tratamiento tienen unas características comunes respecto el contenido, la secuenciación del tratamiento y la elección del antidepresivo. Se prefiere elegir la opción más sencilla, más eficaz y con menor riesgo. Existen diferencias en cuanto al rigor, participación de los implicados y aplicabilidad. Conclusiones. Las guías presentan más similitudes que diferencias. Las diferencias se hallan en las dimensiones rigor y participación. Ante el creciente número de guías y algoritmos se recomienda elegir uno y adaptarlo al territorio donde se interviene (AU)

Objective. Depression accounts for 40% of family doctor consultations. Ways of reorganising the process of care for depression are being looked for by integrating tools such as the use of clinical guidelines and algorithms. It is important to know of one or two tools and to implement them properly. The aim is to analyse and compare the guidelines for the treatment of depression in Primary Care cjinics. Material and methods. We reviewed of the literature found on PubMed and in publications of scientific societies. The guidelines are compared using the Appraisal of Guidelines Research and Evaluation Colaboration. Results. The processing algorithms have some common features regarding the content, sequencing of treatment and choice of antidepressant. The preferred choice should be easier, more efficient and less risk. There are differences in the rigor of the implications and applications. Conclusions. The guidelines have more similarities than differences. The differences are in size and participation rigor. With the increasing number of guidelines and algorithms it is recommended to choose one and adapt it to the area where it will be used (AU)

Utilidad de sildenafilo en disfunciones sexuales secundarias a patología psiquiátrica y psicofármacos / Usefulness of sildenafil in sexual dysfunctions secondary to psychiatric disorders and psychotropic drugs

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