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Int J Dev Neurosci ; 80(3): 189-196, 2020 May.
Artículo en Inglés | MEDLINE | ID: mdl-32065434

RESUMEN

OBJECTIVE: To characterize the spectrum of brain damages presented in children affected by Congenital Zika Syndrome (CZS), verify the existence of a co-occurrence pattern of these damages and discuss possible implications for the neuropsychological development. METHODS: Descriptive, quantitative, individualized, and cross-sectional study using secondary sources. We selected 136 children with CZS from the database of the Center of Strategic Information on Health Vigilance of the Municipal Office of Salvador, Brazil. We conducted descriptive and multiple correspondence analyses. RESULTS: Among the set of analyzed variables, microcephaly (51.5%), ventriculomegaly (57.4%), and brain calcifications (77.2%) were identified as the most frequent. The multiple correspondence analysis showed that the combination of these three variables (32.4%) was what better represented the spectrum of brain damages in the Central Nervous System. INTERPRETATION: Damage in the sensory-motor, cognitive and language development, as well as neurodevelopmental disorders, are described in the literature as impairments associated, either isolated or combined, with these damages, and it is worth highlighting that, in combined brain damages, impairments tend to be more severe. The findings of this study may contribute to understanding the repercussions of CZS on the neuropsychological development of children affected by the epidemic.


Asunto(s)
Encefalopatías/etiología , Encéfalo/diagnóstico por imagen , Calcinosis/etiología , Desarrollo Infantil/fisiología , Microcefalia/etiología , Trastornos del Neurodesarrollo/etiología , Infección por el Virus Zika/complicaciones , Encefalopatías/diagnóstico por imagen , Brasil , Calcinosis/diagnóstico por imagen , Estudios Transversales , Femenino , Humanos , Lactante , Masculino , Microcefalia/diagnóstico por imagen , Trastornos del Neurodesarrollo/diagnóstico por imagen , Neuroimagen
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