RESUMEN
BACKGROUND: Chronic airflow obstruction is a key characteristic of chronic obstructive pulmonary disease. We investigated whether isolated small airways obstruction is associated with chronic airflow obstruction later in life. METHODS: We used longitudinal data from 3957 participants of the multinational Burden of Obstructive Lung Disease study. We defined isolated small airways obstruction using the prebronchodilator mean forced expiratory flow rate between 25% and 75% of the forced vital capacity (FVC) (FEF25-75) if a result was less than the lower limit of normal (Asunto(s)
Obstrucción de las Vías Aéreas
, Enfermedad Pulmonar Obstructiva Crónica
, Humanos
, Estudios Longitudinales
, Enfermedad Pulmonar Obstructiva Crónica/complicaciones
, Enfermedad Pulmonar Obstructiva Crónica/diagnóstico
, Obstrucción de las Vías Aéreas/diagnóstico
, Obstrucción de las Vías Aéreas/etiología
, Capacidad Vital
, Volumen Espiratorio Forzado
