Effect of whole-body vibration stimulation on plasma soluble TNF receptors in elderly with sarcopenia: a randomized controlled trial

Abstract Sarcopenia is a pathology resulting from a progressive and severe loss of muscle mass, strength, and function in the course of aging, which has deleterious consequences on quality of life. Among the most widespread studies on the issue are those focused on the effect of different types of physical exercise on patients with sarcopenia. This randomized controlled study aimed to compare the effects of a whole-body vibration exercise (WBV) session on the inflammatory parameters of non-sarcopenic (NSG, n=22) and sarcopenic elderly (SG, n=22). NSG and SG participants were randomly divided into two protocols: intervention (squat with WBV) and control (squat without WBV). After a one-week washout period, participants switched protocols, so that everyone performed both protocols. Body composition was assessed by dual-energy radiological absorptiometry (DXA) and function through the six-minute walk test (6MWD) and Short Physical Performance Battery (SPPB). Plasma soluble tumor necrosis factor receptors (sTNFR) were determined by enzyme-linked immunosorbent assay (ELISA) and measured before and immediately after each protocol. After exercise with WBV, there was an increase in sTNFR2 levels in the NSG (P<0.01; d=-0.69 (-1.30; -0.08) and SG (P<0.01, d=-0.95 (-1.57; -0.32) groups. In conclusion, an acute session of WBV influenced sTNFr2 levels, with sarcopenic individuals showing a greater effect. This suggested that WBV had a more pronounced impact on sTNFr2 in those with loss of muscle strength and/or physical performance. Additionally, WBV is gaining recognition as an efficient strategy for those with persistent health issues.

Inflammatory biomarkers responses after acute whole body vibration in fibromyalgia

The aims of this study were 1) to characterize the intensity of the vibration stimulation in women diagnosed with fibromyalgia (FM) compared to a control group of healthy women (HW) matched by age and anthropometric parameters, and 2) to investigate the effect of a single session of whole body vibration (WBV) on inflammatory responses. Levels of adipokines, soluble tumor necrosis factor receptors (sTNFr1, sTNFr2), and brain-derived neurotrophic factor (BDNF) were determined by enzyme-linked immunosorbent assay. Oxygen consumption (VO2) was estimated by a portable gas analysis system, heart rate (HR) was measured using a HR monitor, and perceived exertion (RPE) was evaluated using the Borg scale of perceived exertion. Acutely mild WBV increased VO2 and HR similarly in both groups. There was an interaction (disease vs vibration) in RPE (P=0.0078), showing a higher RPE in FM compared to HW at rest, which further increased in FM after acute WBV, whereas it remained unchanged in HW. In addition, there was an interaction (disease vs vibration) in plasma levels of adiponectin (P=0.0001), sTNFR1 (P=0.000001), sTNFR2 (P=0.0052), leptin (P=0.0007), resistin (P=0.0166), and BDNF (P=0.0179). In conclusion, a single acute session of mild and short WBV can improve the inflammatory status in patients with FM, reaching values close to those of matched HW at their basal status. The neuroendocrine mechanism seems to be an exercise-induced modulation towards greater adaptation to stress response in these patients.

Minimal intervention dentistry procedures: a ten year retrospective study.

UNLABELLED: Minimal Intervention Dentistry (MID) is an effective treatment approach with increasing acceptance among dental professionals. OBJECTIVE: This study aimed to evaluate the MID impact on Dentistry by analyzing procedures performed on patients treated at a Pediatric Dentistry Graduate Program clinic which implemented MID. STUDY DESIGN: The number of procedures including sealants, modified atraumatic restorative treatment (mART), resin crowns, direct pulp capping, pulpotomy, pulpectomy, and deciduous/ permanent extractions from 333 pediatric patients treated between the years 2001 to 2003 and 2008 to 2010 in Distrito Federal, Brazil were analyzed. Statistical analysis involved chi-square and G Williams tests. RESULTS: 783 procedures were analyzed and demonstrated that there was a significant reduction of sealant placement in the last triennium when compared to the first one (p<0.0001). Moreover, there was a significant increase in the amount of mART (p<0.0001). This increase in mART procedures resulted in a significant reduction in procedures with pulp involvement: direct pulp capping (p=0.0014), pulpotomy (p=0.0014) and pulpectomy (p=0.0002). CONCLUSIONS: Based on the results, MID represented a positive impact on the intervention on caries lesions in patients, mainly reflected by the significant reduction in the number of direct pulp capping, pulpotomy and pulpectomy.

First record of Neosilba (Diptera: Lonchaeidae) on Jatropha curcas L. in Brazil

Neosilba spp. is firstly reported in physic nut fruits (Jatropha curcas), in Rio Largo, State of Alagoas, Brazil. A total of 438 specimens were found on 1,000 fruits between May and July 2010. Five species were recorded in the State of Alagoas: Neosilba zadolicha McAlpine & Steyskal 1982, Neosilba glaberrima (Wiedemann, 1830), Neosilba certa (Walker, 1850), Neosilba pendula (Bezzi) and Neosilba bella Strikis & Prado 2008. This is the first record of J. curcas as host plant of Neosilba in Brazil.

Relata-se pela primeira vez a ocorrência de Neosilba (Diptera: Lonchaeidae) em frutos de pinhão manso (Jatropha curcas) no Município de Rio Largo, AL, Brasil. O total de 438 exemplares foi obtido de 1.000 frutos entre os meses de maio a julho de 2010. Cinco espécies foram registradas: Neosilba zadolicha McAlpine & Steyskal, 1982 Neosilba glaberrima (Wiedemann, 1830), Neosilba certa (Walker, 1850), Neosilba pendula (Bezzi) e Neosilba bella Strikis & Prado, 2008. Este é o primeiro registro de J. curcas como planta hospedeira de Neosilba no Brasil.

AVALIAÇÃO IN VITRO DO EFEITO DE RIZOBACTÉRIAS SOBRE MELOIDOGYNE INCOGNITA, M. JAVANICA E PRATYLENCHUS ZEAE

ABSTRACT Considering the losses caused by nematodes to different host plant, rhizobacteria are presented as an alternative to to control uch pathogens. So the goal of this study was to evaluate in vitro the action of 20 isolates of rhizobacteria on hatching and motility of second stage juveniles of the Meloidogyne incognita and M. javanica and on the motility of Pratylenchus zeae. The experiment was conducted under laboratory conditions and in a completely randomize design with four replications, and each experimental plot was represented by a hatching chamber. Measurements were spaced every 72 hours. After the evaluations showed that the isolates not influenced the emergence of M. incognita. M. javanica entertaining for isolates FCAV FCAV 8 and 10 showed pronounced ovicidal action. Among the isolates tested on the motility root-knot nematode, only isolates of Bacillus amyloliquefaciens and B. subtilis showed potential as an agent for control of second stage juveniles of M. javanica. When we assessed the motility of isolated active on specimens of .. zeae isolates the FCAV 5, 7 and FCAV B.amyloliquefaciens exhibited potential as agents of biological control of .. zeae. These results confirm that among the rhizobacteria may be found effective agents for the control of nematodes.

RESUMO Considerando as perdas causadas por nematoides às diversas culturas, as rizobactérias se apresentam como uma alternativa para manejar esse patógenos. Assim, o objetivo deste trabalho foi avaliar in vitro a ação de 20 isolados de rizobactérias sobre a eclosão e a motilidade de juvenis de segundo estádio de Meloidogyne incognita e M. javanica e sobre a motilidade de Pratylenchus zeae. O experimento foi instalado em condições de laboratório e em delineamento inteiramente casuali-zado com quatro repetições, constituídas por uma câmara de eclosão cada. As avaliações foram realizadas a cada 72 horas. Após as avaliações observou-se que nenhum dos isolados avaliados influenciaram a eclosão de M. incognita, entretanto para M. javanica, os isolados FCAV 8 e FCAV 10 proporcionaram pronunciada ação ovicida. Entre os isolados testados sobre a motilidade dos nematoides-das-galha apenas os isolados de Bacillus amyloliquefaciens e B. subtillis evidenciaram potencial como agente do controle de juvenis de segundo estádio de M. javanica. Quando se avaliou a motilidade dos isolados sobre espécimes ativos de .. zeae, obsevou-se que os isolados FCAV 5, FCAV 7 e B. amyloliquefaciens exibiram potencial como agentes do controle biológico de .. zeae. Estes resultados confirmam que entre as rizobactérias podem ser encontrados agentes eficazes para o controle de nematoides.