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1.
Clin Neurol Neurosurg ; 206: 106686, 2021 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-34053804

RESUMEN

OBJECT: Optimal surgical technique to restore the cerebrospinal fluid flow through the foramen magnum remains to be debated in Chiari malformation type 1 (CM-1) patients. METHOD: This study included 46 patients with CM-1 who underwent surgical treatment by one of two methods: posterior fossa bone decompression (BD) with arachnoid preserving duraplasty (Group 1) and BD with duraplasty and arachnoid dissection (Group 2). Complaints of the patient population and neurological findings were assessed with Neck Disability Index (NDI) and Europe Quality of Life 5 Dimensions (EQ-5D) in pre- and postoperative periods. RESULTS: NDI and EQ-5D scores improved in overall patient population and in each individual surgical group. Both groups showed a significant decrease in size of syringomyelia cavity. Complications resulting in recurrent treatments and re-operations occurred in 15% of patients (n = 7); six of them were from Group 2. CONCLUSION: CM-1 patients benefit significantly from surgical treatment. Duraplasty should be included to surgical technique. Avoiding arachnoid dissection may lead to better results regarding complication rates.


Asunto(s)
Aracnoides/cirugía , Malformación de Arnold-Chiari/cirugía , Duramadre/cirugía , Procedimientos Neuroquirúrgicos/métodos , Adolescente , Adulto , Anciano , Descompresión Quirúrgica/métodos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven
2.
World Neurosurg ; 147: e444-e452, 2021 03.
Artículo en Inglés | MEDLINE | ID: mdl-33373739

RESUMEN

OBJECTIVE: Fluorescein sodium (FNa) videoangiography (VA) was performed to evaluate blood flow within vessels and exclusion of the aneurysm after surgical clipping of intracranial aneurysms. The aim of this study was to report results of FNa-VA in a case series, including benefits and limitations of the technique, and compare intraoperative findings with postoperative cerebral angiography to assess reliability of FNa-VA. METHODS: The study included 64 aneurysms in 50 consecutive patients. Following clip ligation of the aneurysm, 100 mg of FNa was administered intravenously. The microscope light was switched to the FL560 integrated fluorescence module. Aneurysm sac, parent arteries, and perforating arteries were observed. RESULTS: FNa-VA promoted real-time assessment of the surgical field in three-dimensional view through the binoculars with good image quality. In 79.68% of aneurysms, FNa-VA confirmed satisfactory clip application, as FNa did not penetrate into the aneurysm. In 14.06% of aneurysms, a homogeneous yellow-green color change occurred, which was accepted as a false-positive sign. In 6.25% of aneurysms, FNa seeped into the aneurysm emitting a heterogeneous green signal, which slowly dispersed throughout the sac. Postoperative angiography revealed satisfactory results. Small neck remnants were present in 5 patients, and mild parent artery stenosis was found in 3 patients. No ischemic event occurred secondary to parent artery or perforating artery occlusion. CONCLUSIONS: FNa-VA adds greatly to the safety of surgical treatment of intracranial aneurysms, particularly in lesions situated in deep locations, by enabling real-time inspection, which facilitates safer manipulation and evaluation of structures in question.


Asunto(s)
Angiografía Cerebral , Colorantes , Fluoresceína , Aneurisma Intracraneal/cirugía , Adulto , Anciano , Arterias/patología , Arterias/cirugía , Angiografía Cerebral/métodos , Femenino , Fluoresceína/uso terapéutico , Humanos , Masculino , Persona de Mediana Edad , Monitoreo Intraoperatorio/métodos , Procedimientos Neuroquirúrgicos/métodos , Reproducibilidad de los Resultados , Procedimientos Quirúrgicos Vasculares/métodos
3.
JAAPA ; 33(11): 29-31, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-33109980

RESUMEN

Chondrosarcoma, a malignant bone tumor, is rarely encountered in the cervical spine. This article describes a patient whose neck pain and dysphagia were caused by an expansive, destructive lesion with calcification that was located in the body of the axis (C2 vertebra), the first time a chondrosarcoma has been reported in this location.


Asunto(s)
Vértebra Cervical Axis/cirugía , Condrosarcoma/cirugía , Endoscopía/métodos , Neoplasias de la Columna Vertebral/cirugía , Adulto , Vértebra Cervical Axis/diagnóstico por imagen , Vértebra Cervical Axis/patología , Vértebras Cervicales , Condrosarcoma/diagnóstico por imagen , Condrosarcoma/patología , Imagen de Difusión por Resonancia Magnética , Femenino , Humanos , Neoplasias de la Columna Vertebral/diagnóstico por imagen , Neoplasias de la Columna Vertebral/patología , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
4.
World Neurosurg ; 144: e568-e575, 2020 12.
Artículo en Inglés | MEDLINE | ID: mdl-32916363

RESUMEN

BACKGROUND: The corpus callosotomy (CCT) has been reported as an effective procedure to alleviate drop attacks. However, the extent of CCT remains debatable. Classical studies suggest that motor fibers traverse mainly through the anterior half of the corpus callosum (CC), although recent diffusion tensor imaging studies described that motor fibers crossed the CC in a more posterior location, emphasizing the posterior midbody and the isthmus. METHODS: Cortical and subcortical structures were examined in 30 hemispheres prepared for white matter fiber dissection. Dissections were carried out under surgical magnification to trace fibers originating from the primary motor cortex and their course through the CC. The distance of the most anterior and posterior motor fibers to the tip of the genu were measured, and the extent of CCT enabling disconnection of all motor fibers was calculated. RESULTS: Motor fibers coursed through the posterior half of the CC in the majority of hemispheres, mainly locating in posterior midbody and the isthmus. Callosal fibers should be interrupted to an average of 61% ± 0.07% point of the CC to reach the anterior limit of motor fibers and to an average of 69% ± 0.07% point to include posterior limit of motor fibers. Motor fibers were extending until the posterior one third of the CC in 22 specimens. CONCLUSIONS: Anterior-half CCT did not include all motor fibers in any specimen. Anterior two thirds CCT disrupted all motor fibers in one fourth of the cases. Our findings suggest that an ideal CCT should extend to the posterior midbody and isthmus of the CC.


Asunto(s)
Cuerpo Calloso/anatomía & histología , Cuerpo Calloso/cirugía , Corteza Motora/anatomía & histología , Corteza Motora/cirugía , Sustancia Blanca/anatomía & histología , Sustancia Blanca/cirugía , Humanos , Vías Nerviosas/anatomía & histología , Vías Nerviosas/cirugía , Procedimientos Neuroquirúrgicos
5.
Turk J Phys Med Rehabil ; 65(1): 74-79, 2019 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-31453546

RESUMEN

OBJECTIVES: We aimed to evaluate balance using the Tetrax Interactive Balance System (TIBS) in patients with Chiari type I malformation (CM-I) and to assess their fall risk with other clinical parameters. PATIENTS AND METHODS: This cross-sectional, prospective study was conducted at physical medicine and rehabilitation outpatient clinics and neurosurgery department of a university hospital between December 2013 and December 2014. The study included a total of 36 patients (31 females, 5 males; mean age 40.6±10.0 years; range, 18 to 60 years) with CM-I. Dynamic balance was assessed using the Berg Balance Scale (BBS), and posturographic examinations were performed using the TIBS. RESULTS: The mean Fall Risk Index (FI) value was 42.4±29.8 and the mean BBS score was 55.5±1.5. The most common complaints were neck pain (94.4%), headache (88.9%), paresthesia (86.1%), fatigue (83.3%), and vertigo (80.6%). The mean tonsillar herniation below the foramen magnum was 8.7±3.8 (mm). Of the patients, 15 (42.85%) had syringomyelia. The degree of tonsillar ectopia was statistically significantly lower in patients with syringomyelia (p<0.05). The BBS scores were near identical among the patients with or without syringomyelia, although the FI values were lower in the patients with syringomyelia. Comparing cerebellar ectopia ≤9 mm versus >10 mm, the FI values were slightly higher in the patients with ectopia >10 mm, although there was no statistically significant difference in the FI or BBS values. CONCLUSION: Our study results suggest that CM-I can decrease the body balance stability and, thus, increase the fall risk. Evaluation of balance in patients with CM using TIBS static posturography is a simple and effective technique.

6.
Neuroradiology ; 61(2): 195-205, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-30488257

RESUMEN

PURPOSE: There are no established guidelines for treatment of Spetzler-Martin grade III-V brain arteriovenous malformations (bAVMs). The purpose of this study is to report our institutional experience in total obliteration/eradication of grade III-V bAVMs by single-stage planning of embolization combined with microsurgical resection when necessary. METHODS: All patients harboring Spetzler-Martin (S-M) grade III-V bAVMs treated with single-stage planning between January 2006 and January 2018 were retrospectively reviewed. This treatment paradigm is applicable only to surgically accessible bAVMs and does not include deep-seated bAVMs. Indications for treatment, clinical presentation, imaging characteristics, and treatment outcomes were analyzed. Outcomes were assessed based on modified Rankin Scale. RESULTS: A total of 31 patients were identified. Seventeen patients (54.8%) presented with hemorrhage, 10 (32.3%) with seizures, 3 (9.7%) with headaches, and 1 (3.2%) with progressive neurological deficit. Based on S-M grading system, 25 patients (80.6%) harbored grade III bAVM, 5 patients had grade IV bAVMs (16.1%), and 1 patient (3.2%) had a grade V bAVM. There were no treatment-related complications in 24/31 (77.4%) patients. Of the total of seven patients with complications, four patients had clinical deterioration. The long-term (> 6-month), non-disabling morbidity (mRS ≤ 2) rate was 6.5%. The long-term, disabling morbidity rate was 3.2% with a mortality of 3.2%. Complete angiographic obliteration was achieved in 30/31 (96.8%) patients. CONCLUSION: Single-stage treatment strategy can be considered as an alternative to multistage embolization prior to surgery in grade III-V bAVMs. In this study, a high rate of total obliteration with relatively low rates of permanent morbidity and mortality was achieved.


Asunto(s)
Embolización Terapéutica/métodos , Malformaciones Arteriovenosas Intracraneales/diagnóstico por imagen , Malformaciones Arteriovenosas Intracraneales/terapia , Procedimientos Neuroquirúrgicos , Adulto , Anciano , Anciano de 80 o más Años , Angiografía de Substracción Digital , Angiografía Cerebral , Terapia Combinada , Evaluación de la Discapacidad , Femenino , Humanos , Masculino , Microcirugia , Persona de Mediana Edad , Estudios Retrospectivos , Resultado del Tratamiento
7.
World Neurosurg ; 118: e473-e482, 2018 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-29981913

RESUMEN

OBJECTIVE: To review the results of sphenoid sinus lateral recess (SSLR) cerebrospinal fluid (CSF) leaks treated with the endoscopic endonasal minimal transpterygoid approach (EEMTPA) and to discuss the surgical technique and outcomes. METHODS: We performed a retrospective analysis of 13 cases who underwent SSLR CSF leak repair through the EEMTPA in our clinic between September 2008 and December 2017. Demographic and etiological features with reconstruction and surgical outcomes were examined. Mean follow-up time was 6.1 years. RESULTS: In regard to etiology, the SSLR CSF leaks included 9 patients with spontaneous, 2 patients with traumatic, and 2 with iatrogenic causes. CSF leak was at the left lateral recess in 8 cases and at right lateral recess in 5 cases. Nine patients had empty sella syndrome, and 11 patients had meningoencephaloceles in addition to SSLR CSF leaks. All patients underwent surgery through the EEMTPA, and a multilayer closure with tissue overlay grafts were used for reconstruction. A pedicled nasoseptal flap and/or pedicled middle turbinate flap were applied to the area of the leak in all cases. One patient had a persistent CSF leak and another had recurrence, both of which required revision surgery. Our overall success rate was 100%. CONCLUSIONS: EEMTPA is a safe and effective method that can be used to treat challenging pathologies at the SSLR, including CSF leaks accompanying meningoencephaloceles. Furthermore, the success rate of EEMTPA for SSLR CSF leaks can be increased by applying endoscopic skull base reconstruction techniques such as the pedicled nasoseptal flap and pedicled middle turbinate flap.


Asunto(s)
Pérdida de Líquido Cefalorraquídeo/cirugía , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Cavidad Nasal/cirugía , Neuroendoscopía/métodos , Procedimientos Neuroquirúrgicos/métodos , Seno Esfenoidal/cirugía , Adolescente , Adulto , Anciano , Pérdida de Líquido Cefalorraquídeo/diagnóstico por imagen , Preescolar , Manejo de la Enfermedad , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Cavidad Nasal/diagnóstico por imagen , Músculos Pterigoideos/diagnóstico por imagen , Músculos Pterigoideos/cirugía , Estudios Retrospectivos , Seno Esfenoidal/diagnóstico por imagen , Trasplante Autólogo/métodos
8.
Turk Neurosurg ; 28(2): 193-203, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-28481397

RESUMEN

AIM: To present the results of endoscopic endonasal repair of ventral midline skull base cerebrospinal fluid (CSF) leak (VMSBL) at our institution and to discuss the technique and results from a neurosurgical perspective. MATERIAL AND METHODS: A retrospective analysis of all VMSBL cases that underwent endoscopic endonasal skull base approach (EESBA) for CSF leak repair at a single tertiary neurosurgical center was performed. Twenty six patients with an average age of 44.4 (range: 17-63) years were included in the study. RESULTS: The etiology of VMSBL was spontaneous in 16 patients, traumatic in 7, and iatrogenic in 3. The leakage site was the cribriform plate in 13 patients, ethmoidal cells in 7, and sphenoid sinus in 3. There were multiple leaks in 3 patients. This approach for VMSBL repair was performed 28 times on 26 patients. The success rate was 88.5% (23/26 patients) after primary endoscopic repair and 96% after the second attempt. The location of the leakage site relative to the upper attachment of the middle turbinate played a crucial role in the anteriorly located VMSBL, which made an impact on the surgical repair plan. All the 16 cases with accompanying meningoencephaloceles were treated successfully by EESBA. Use of vascularized pedicled flaps to support the repair site resulted in 100% success after primary repair. CONCLUSION: EESBA is safe and highly effective and can be a first-line surgical treatment option for VMSBL. In addition, it enables adequate reconstruction of ventral midline skull base meningoencephaloceles regardless of size and location.


Asunto(s)
Pérdida de Líquido Cefalorraquídeo/cirugía , Neuroendoscopía/métodos , Base del Cráneo/cirugía , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Resultado del Tratamiento , Adulto Joven
9.
Turk Neurosurg ; 25(2): 210-7, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26014002

RESUMEN

AIM: Awake craniotomy (AC) with electrical cortical stimulation has become popular during the last ten years although the basic principles were introduced almost 50 years ago. The aim of this paper is to share with the readers our experience in 25 patients who underwent AC with electrical stimulation. MATERIAL AND METHODS: Twenty-five patients who underwent AC between 2010 and 2013 are the subjects of this paper. All patients were diagnosed with intraaxial lesions involving the functional area itself or very close to it by preoperative imaging. During surgery, the functional area was demonstrated by cortical electrical stimulation and resection aimed to preserve it in order to avoid an irreversible functional deficit. RESULTS: Total resection was possible in 80% while in 20% subtotal resection had to be performed because of involvement of the functional area itself. The neurological complication rate was found to be 16% (4 patients) and all were transient. No complication regarding anesthesia was noted. CONCLUSION: Awake craniotomy in selected patients is very effective, safe and practical for supratentorial lesions close to the eloquent area. Complications related to the surgery itself are uncommon and general anesthesia is avoided. The hospital stay including the intensive care unit is short which makes it very economical surgical procedure.


Asunto(s)
Neoplasias Encefálicas/cirugía , Craneotomía/métodos , Epilepsia/cirugía , Monitorización Neurofisiológica Intraoperatoria/métodos , Malformaciones del Desarrollo Cortical/cirugía , Vigilia/fisiología , Adulto , Anciano , Corteza Cerebral/fisiología , Corteza Cerebral/fisiopatología , Corteza Cerebral/cirugía , Craneotomía/efectos adversos , Estimulación Eléctrica/métodos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Resultado del Tratamiento
10.
J Craniofac Surg ; 25(4): 1524-8, 2014 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-24914756

RESUMEN

OBJECT: Promising clinical results were reported in watertight closure of anterior skull base defects (ASBDs) with bisphenol-a-glycidyl-dimethacrylate (bis-GMA)-based materials to prevent the cerebrospinal fluid leaks. However, interrelation of these materials with surrounding bones in histologic level, referred to as the osteointegration, has not been reported in the anterior skull base. In addition, an illustrative case with an ASBD that was repaired using a bis-GMA composite has been presented. METHODS: Twenty New Zealand rabbits were divided into 4 groups: control and sham groups consisted of 2 and 6 rabbits, respectively. The "skull base defect" group (n = 6) underwent a unifrontal craniectomy and an iatrogenic ASBD followed by creating a dural defect to obtain a cerebrospinal fluid leak. Similar bony and dural defects were acquired in the "repair with bis-GMA based allograft" group (n = 6), but the bony defect was closed with bis-GMA-based allograft. RESULTS: All animals in the "skull base defect" group died in 3 weeks after surgery. There were no animal losses in the "repair with bis-GMA based allograft" group at the sixth month. Histologic evaluation revealed complete osteointegration of bis-GMA composite with surrounding bones. CONCLUSIONS: bis-GMA based allograft achieved a watertight repair of the ASBD. Histologic findings of this study showed that bis-GMA composite is a reliable material to be used in the closure of anterior skull base bony defects.


Asunto(s)
Bisfenol A Glicidil Metacrilato/uso terapéutico , Cementos para Huesos/uso terapéutico , Pérdida de Líquido Cefalorraquídeo/cirugía , Oseointegración/fisiología , Base del Cráneo/cirugía , Adulto , Animales , Enfermedades Óseas/cirugía , Modelos Animales de Enfermedad , Estudios de Seguimiento , Hueso Frontal/lesiones , Hueso Frontal/cirugía , Humanos , Masculino , Senos Paranasales/lesiones , Conejos , Propiedades de Superficie , Heridas por Arma de Fuego/cirugía
11.
Acta Neurochir (Wien) ; 156(1): 53-61, 2014 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-24173470

RESUMEN

BACKGROUND: To present the combined treatment of fusiform basilar artery aneurysms consisting of a surgical posterior fossa decompressive craniectomy and ventriculoperitoneal (VP) shunt operation at the same sitting, before the endovascular procedure with telescopic stenting of the aneurysmatic vessel segment in four cases. METHODS: Combined treatment involving surgical procedure consisting of ventriculoperitoneal shunt placement for hydrocephalus and an occipital bone craniectomy and C1 vertebrae posterior laminectomy to decompress the posterior fossa in the same session. After surgery, the patients were loaded with acetylsalicylic acid and clopidogrel, and then the endovascular treatment was performed. RESULTS: All of the procedures were performed successfully without technical difficulty. The patients tolerated the procedures well and all cases showed remodelling with the overlapping stent technique. The patients were discharged home with baseline neurological situation and computed tomography (CT) angiography was performed at the 3rd month. CONCLUSION: This technique is a safer endovascular approach to treating symptomatic fusiform basilar artery aneurysms by protecting patients from both the haemorrhagic complications of anticoagulant therapy and thrombotic complications due to the interruption of anticoagulant therapy, while treating the hydrocephalus and compression by surgical means.


Asunto(s)
Aneurisma/cirugía , Embolización Terapéutica , Aneurisma Intracraneal/terapia , Stents , Adulto , Anciano , Aneurisma/diagnóstico por imagen , Angiografía Cerebral/métodos , Embolización Terapéutica/métodos , Humanos , Aneurisma Intracraneal/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/prevención & control , Resultado del Tratamiento
12.
Neurosurg Rev ; 35(4): 573-82; discussion 582, 2012 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-22527631

RESUMEN

In this article, the authors are presenting their experience and the results with the surgical treatment of intraorbital intraconal tumors based on a review of 33 constitutive cases. Our data were evaluated in comparison to other major series, and possible factors that might influence surgical outcome and survival are discussed. Thirty-three patients diagnosed with intraorbital intraconal tumors between 1998 and 2009 were treated by transcranial approach. Of these patients, there were 14 males (42.4 %) and 19 females (57.8 %). The age ranged between 2 and 70 years (mean = 36 ± 16.6 years). The follow-up period ranged between 2 and 13 years (mean = 7.3 ± 3.2 years). The most common presenting symptoms were exophthalmus and decreased visual acuity, which was seen in 21 (63.6 %) and 19 patients (57.6 %), respectively. Total resection was achieved in 23 patients (69.7 %) while subtotal resection was done in ten patients (30.3 %). Cavernoma and optic nerve sheath meningioma were the most common histologic variants, which were found in 11 (33.3 %) and 10 (30.3 %) patients, respectively. In the long-term follow-up, 54.5 % of the patients showed total ophthalmologic improvement, 9.1 % showed partial improvement, 21.2 % demonstrated unchanged ophthalmologic status, and 15.2 % showed worse ophthalmologic outcome. Transcranial approach for the treatment of intraorbital intraconal tumors is an effective approach for the management of these pathologies. The effectiveness is clearly demonstrated by the clinical results and outcomes of these patients' groups.


Asunto(s)
Procedimientos Neuroquirúrgicos/métodos , Órbita/cirugía , Neoplasias Orbitales/cirugía , Adolescente , Adulto , Anciano , Niño , Preescolar , Femenino , Humanos , Imagen por Resonancia Magnética , Masculino , Meningioma/cirugía , Microcirugia , Persona de Mediana Edad , Neoplasias del Nervio Óptico/cirugía , Neoplasias Orbitales/patología , Neoplasias Orbitales/secundario , Periodo Posoperatorio , Sobrevida , Resultado del Tratamiento , Trastornos de la Visión/etiología , Agudeza Visual , Campos Visuales/fisiología , Adulto Joven
13.
J Neurosci Rural Pract ; 2(2): 162-7, 2011 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-21897681

RESUMEN

Cranioplasty is the surgical intervention to repair cranial defects. The aim of cranioplasty is not only a cosmetic issue; also, the repair of cranial defects gives relief to psychological drawbacks and increases the social performances. Many different types of materials were used throughout the history of cranioplasty. With the evolving biomedical technology, new materials are available to be used by the surgeons. Although many different materials and techniques had been described, there is still no consensus about the best material, and ongoing researches on both biologic and nonbiologic substitutions continue aiming to develop the ideal reconstruction materials. In this article, the principle materials and techniques of cranioplasty are reviewed.

14.
Turk Neurosurg ; 21(2): 249-53, 2011.
Artículo en Inglés | MEDLINE | ID: mdl-21534213

RESUMEN

Primary fourth ventricle meningiomas are extremely rare, and they are defined as meningiomas arising from the choroid plexus and lying strictly within the fourth ventricle. In this report we present a 61-year-old man with progressive worsening vertigo and gait disturbance, and new onset of diplopia. Neurological examination revealed bilateral abducens nerve paralysis, horizontal nystagmus, and gait disturbance with truncal ataxia. Neuroimaging revealed a mass lesion in the fourth ventricle with brain stem compression, and obstructive hydrocephalus. The patient was operated in the prone position with suboccipital craniotomy and splitting the lower vermis. Total resection of the tumor was achieved with no intra- or post-operative complications. Histopathologic examination revealed fibroblastic type meningioma (WHO grade I).


Asunto(s)
Neoplasias del Plexo Coroideo/cirugía , Cuarto Ventrículo/cirugía , Neoplasias Meníngeas/cirugía , Meningioma/cirugía , Neoplasias del Plexo Coroideo/patología , Cuarto Ventrículo/patología , Humanos , Imagen por Resonancia Magnética , Masculino , Neoplasias Meníngeas/patología , Meningioma/patología , Persona de Mediana Edad
15.
Neurosurg Rev ; 34(1): 101-13, 2011 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-20878534

RESUMEN

In this article, the authors are presenting their experience and the results with combined craniofacial resection of anterior skull base tumors based on a review of 27 constitutive cases. Our data are evaluated in comparison to other major centers in other parts of the world, and possible factors that might influence surgical outcome and survival are discussed. Twenty-seven patients diagnosed with anterior skull base tumors between 1999 and 2009 were treated by combined craniofacial resection. Of these patients, there were 19 males (70, 3%) and eight females (29, 7%). The age ranged between 11 and 75 years (mean = 45.9 ± 17.6 years). The follow-up period ranged between 14 and 123 months (avarage = 74 months). The most common presenting symptoms were nasal obstruction and vision disturbance (11 patients for each -40.7%). Total resection was achieved in 24 patients (89%), while subtotal resection was done in three patients (11%). The most common complication was CSF fistule with rhinorrhea, which occurred in five patients (18.5%). Eight patients had recurrences at the time of this long-term follow-up. There were two mortalities in the early postoperative period and seven deaths in the long-term follow-up (overall mortality, 33.3%). The overall 5-year overall survival for all patients in our series was 70.4%. The 5-year overall survival was 62% for patients with malignant tumors and 100% for patients with benign tumors. Combined craniofacial resection of tumors of the anterior skull base is an effective approach for the management of these pathologies. The effectiveness is clearly demonstrated by the clinical results and outcomes of these patients' groups. The favorable prognosis is enhanced by significantly by total resection with negative tumor margins.


Asunto(s)
Cara/cirugía , Cabeza/cirugía , Procedimientos Neuroquirúrgicos/métodos , Neoplasias de la Base del Cráneo/cirugía , Adolescente , Adulto , Anciano , Anestesia General , Niño , Femenino , Estudios de Seguimiento , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Obstrucción Nasal/etiología , Recurrencia Local de Neoplasia/epidemiología , Complicaciones Posoperatorias/epidemiología , Neoplasias de la Base del Cráneo/complicaciones , Neoplasias de la Base del Cráneo/patología , Análisis de Supervivencia , Tomografía Computarizada por Rayos X , Resultado del Tratamiento , Trastornos de la Visión/etiología , Adulto Joven
16.
J Craniofac Surg ; 21(3): 936-9, 2010 May.
Artículo en Inglés | MEDLINE | ID: mdl-20485089

RESUMEN

A 45-year-old woman described the pain and the swelling at the left frontoparietal region. No significant findings were noted on physical examination, except a heterogeneous palpable lesion at the described region. Computed tomographic scan revealed an expansive bone lesion with homogeneous density, whereas magnetic resonance imaging revealed similar findings with no contrast enhancement. The lesion was totally resected, and cranioplasty with a porous polyethylene sheet (Medpor Biomaterial; Porex Surgical, Newnan, GA) was achieved. Histopathologic examination revealed an intraosseous meningioma. As far as we know, this case is the first case, in which total excision of the interosseous meningioma is followed by reconstruction with Medpor.


Asunto(s)
Materiales Biocompatibles , Neoplasias Meníngeas/cirugía , Meningioma/cirugía , Polietilenos , Femenino , Humanos , Imagen por Resonancia Magnética , Neoplasias Meníngeas/diagnóstico , Meningioma/diagnóstico , Persona de Mediana Edad , Polietileno , Tomografía Computarizada por Rayos X
17.
J Craniofac Surg ; 21(2): 529-37, 2010 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-20489457

RESUMEN

OBJECTIVES: The objective of this study was to review the endoscopic anatomy of the anterior skull base, defining the pitfalls of endoscopic endonasal approaches to this region. Recently, these approaches are gaining popularity among neurosurgeons, and the details of the endoscopic anatomy and approaches are highlighted from the neurosurgeons' point of view, correlated with demonstrative cases. MATERIALS AND METHODS: Twelve fresh adult cadavers were studied (n = 12). We used Karl Storz 0 and 30 degrees, 4 mm, 18- and 30-cm rod lens rigid endoscope in our dissections. After preparation of the cadaveric specimens, we approached the anterior skull base by the extended endoscopic endonasal approach. RESULTS: After resection of the superior portion of the nasal septum, bilateral middle and superior turbinates, and bilateral anterior and posterior ethmoidal cells, we could obtain full exposure of the anterior skull base. The distance between optic canal and the posterior ethmoidal artery ranged from 8 to 16 mm (mean, 11.08 mm), and the distance between posterior ethmoidal artery and the anterior ethmoidal artery ranged from 10 to 17 mm (mean, 13 mm). After resecting the anterior skull base bony structure and the dura between the 2 medial orbital walls, we could visualize the olfactory nerves, interhemispheric sulcus, and gyri recti. With dissecting the interhemispheric sulcus, we could expose the first (A1) and second (A2) segments of the anterior cerebral artery, anterior communicating artery, and Heubner arteries. CONCLUSIONS: This study showed that extended endoscopic endonasal approaches are sufficient in providing wide exposure of the bony structures, and the extradural and intradural components of the anterior skull base and the neighboring structures providing more controlled manipulation of pathologic lesions. These approaches need specific skill and learning curve to achieve more minimally invasive interventions and less postoperative complications.


Asunto(s)
Endoscopía/métodos , Procedimientos Neuroquirúrgicos/métodos , Base del Cráneo/cirugía , Adulto , Arteria Cerebral Anterior/anatomía & histología , Arterias/anatomía & histología , Cadáver , Rinorrea de Líquido Cefalorraquídeo/cirugía , Cerebro/anatomía & histología , Círculo Arterial Cerebral/anatomía & histología , Disección/instrumentación , Disección/métodos , Duramadre/cirugía , Endoscopios , Hueso Etmoides/irrigación sanguínea , Hueso Etmoides/cirugía , Femenino , Adhesivo de Tejido de Fibrina/uso terapéutico , Estudios de Seguimiento , Lóbulo Frontal/anatomía & histología , Humanos , Masculino , Persona de Mediana Edad , Tabique Nasal/cirugía , Nervio Olfatorio/anatomía & histología , Órbita/cirugía , Procedimientos de Cirugía Plástica/métodos , Base del Cráneo/anatomía & histología , Adhesivos Tisulares/uso terapéutico , Cornetes Nasales/cirugía
18.
J Craniofac Surg ; 21(1): 233-8, 2010 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-20072003

RESUMEN

OBJECTIVE: The anterior skull base is a location of many pathologic lesions. These pathologic lesions are treated by bifrontal craniotomy and anterior skull base approach, either primarily or combined with facial osteotomies. To obtain wide exposure, low-profile craniotomies are preferred. In this article, we attempt to describe our own technique of frontal craniotomy for anterior skull base approach. In this technique, the frontal bone, frontal sinus, and the superior supraorbital bar are elevated in en bloc fashion. METHODS: Bicoronal skin incision is followed by dissection and retraction of the skin flap in the epigaleal plan. The pericranial galeal flap is dissected separately in subperiosteal fashion until the superior orbital rim. After dissection and retraction of the tip of the temporal muscles, bilateral pterional key burr holes and 1 or 2 parasagittal burr holes are opened. The sagittal burr hole(s) is placed in the point where the upper horizontal surface of the frontal bone slopes vertically downward the forehead. With the craniotome rotating tip (Midas F2/8TA23, Medtronic Inc, Ft Worth, TX), bone cut is made between the pterional key burr holes, passing through the superior orbital bar and the anterior wall of the frontal sinus. To minimize the brain retraction, the operating microscope is placed beside the head, and exposure from the lateral view angle is obtained. Reconstruction of the defect is performed by using pericranial galeal flap and/or Cortoss (Orthovita, Malvern, PA). RESULTS: With this approach, wide exposure of the anterior skull base pathologic lesions was achieved with minimal brain retraction. In the postoperative period, patients tolerated this approach well with favorable functional and cosmetic outcomes. No infections or adverse effects related to this technique or Cortoss were observed. CONCLUSIONS: Anterior skull base pathologic lesions can be widely exposed by low-profile bicoronal craniotomy and anterior skull base approach with minimal brain retraction. This wide exposure allows us to gain more control of the pathologic lesion with better resection and reconstruction, reflected on the prognosis of the patients.


Asunto(s)
Craneotomía/métodos , Procedimientos de Cirugía Plástica/métodos , Neoplasias de la Base del Cráneo/cirugía , Craneotomía/instrumentación , Humanos , Procedimientos de Cirugía Plástica/instrumentación , Colgajos Quirúrgicos
20.
J Craniofac Surg ; 20(4): 1245-9, 2009 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-19553832

RESUMEN

OBJECTIVE: In growing skull fractures with large calvarial defects, it is difficult to use autografts for reconstruction and it requires alternative materials for cranioplasty. In this report, the authors describe their experience and introduce reconstruction of the growing skull fractures' defects with a porous polyethylene sheet (Medpor) and with a novel technique of duraplasty with in situ galeal graft, which avoid the potentially risky dissection and exposure of brain tissue. The goal of this study was to clarify effective surgical methods and to provide the rationale for these techniques. METHODS: We performed this technique on 8 patients with large calvarial defects resulting from growing skull fractures. The skin flap was retracted, leaving the galeal plane adherent to the underlying defect. After removing the bony edges and exposing the underlying retracted dural margins, duraplasty was performed by suturing the galeal tissue left in situ on the defect of the dural margins. Bone reconstruction was performed by placing porous polyethylene sheet (Medpor). CONCLUSIONS: Duraplasty with in situ galeal tissue is a simple, safe, and effective technique to reconstruct dural defects in growing skull fracture, which avoids the risky dissection of the brain tissue. Also, by using Medpor, growing skull fractures can be effectively reconstructed with good cosmetic results.


Asunto(s)
Fijación Interna de Fracturas/métodos , Procedimientos de Cirugía Plástica/métodos , Polietilenos , Fracturas Craneales/cirugía , Materiales Biocompatibles , Niño , Preescolar , Duramadre/cirugía , Femenino , Humanos , Lactante , Masculino , Porosidad , Resultado del Tratamiento , Adulto Joven
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