1.
Nucleosides Nucleotides Nucleic Acids
; 19(8): 1355-64, 2000 Aug.
Artículo
en Inglés
| MEDLINE
| ID: mdl-11097064
RESUMEN
Double-stranded DNA fixed in a cholesteric liquid-crystalline dispersion was used for generating an ordered supramolecular structure in the presence of anthracycline and copper (II) ions. The structure is stable in a water-salt solution and does not require poly(ethyleneglycol).The ordered network can be immobilized on the surface of a polymeric film, and may collapse in the presence of biologically and pharmacologically relevant compounds. Accordingly, the DNA-based liquid-crystalline network represents the basis to obtain novel highly sensitive biosensing units.