Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Más filtros











Base de datos
Intervalo de año de publicación
1.
Adv Nutr ; 15(7): 100252, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38876397

RESUMEN

Impaired lipid metabolism is a pivotal driver of cardiovascular disease (CVD). In this regard, the accumulation of ceramides within the circulation as well as in metabolically active tissues and atherosclerotic plaques is a direct consequence of derailed lipid metabolism. Ceramides may be at the nexus between impaired lipid metabolism and CVD. Indeed, although on one hand ceramides have been implicated in the pathogenesis of CVD, on the other specific ceramide subspecies have also been proposed as predictors of major adverse cardiovascular events. This review will provide an updated overview of the role of ceramides in the pathogenesis of CVD, as well as their pathogenetic mechanisms of action. Furthermore, the manuscript will cover the importance of ceramides as biomarkers to predict cardiovascular events and the role of diet, both in terms of nutrients and dietary patterns, in modulating ceramide metabolism and homeostasis.


Asunto(s)
Enfermedades Cardiovasculares , Ceramidas , Dieta , Metabolismo de los Lípidos , Ceramidas/metabolismo , Humanos , Enfermedades Cardiovasculares/etiología , Biomarcadores/sangre , Animales , Homeostasis
2.
Heart Fail Clin ; 19(1): 11-24, 2023 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-36435566

RESUMEN

Biological sex and sociocultural gender are emerging as pivotal modifiers of health and diseases. Sex-based differences exist in the development, pathogenesis, and management of individuals with pulmonary arterial hypertension (PAH). The interplay between gender domains (ie, identity, roles, relations, and institutionalized gender) and PAH has been barely investigated. The aim of this narrative review is to describe up-to-date evidence on the integration of sex and gender in PAH research, highlighting areas for future investigation.


Asunto(s)
Hipertensión Pulmonar , Masculino , Femenino , Humanos , Hipertensión Pulmonar/epidemiología , Hipertensión Pulmonar/terapia , Caracteres Sexuales
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA