Asunto(s)
Síndrome de Birt-Hogg-Dubé/complicaciones , Melanoma/complicaciones , Neoplasias Cutáneas/complicaciones , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Síndrome de Birt-Hogg-Dubé/genética , Niño , Femenino , Filaminas/genética , Humanos , Masculino , Melanoma/genética , Persona de Mediana Edad , Mutación/genética , Neoplasias Cutáneas/genética , Adulto Joven , Melanoma Cutáneo MalignoRESUMEN
PURPOSE: The gold standard for measuring intraocular pressure (IOP) until now has been Goldmann applanation tonometry (GAT), which depends on the central corneal thickness (CCT) and curvature. In patients with keratoconus who have an abnormal corneal geometry and thickness, measurement of pressure with GAT is often difficult and not very reproducible. We compared the impact of the central corneal thickness (CCT) on the IOP measured with dynamic contour tonometry (DCT), a digital method which is adapted to the corneal geometry, and GAT in patients with keratoconus. METHODS: IOP was measured in 54 patients (38 men and 16 women, mean age of 36+/-9.9 years) with GAT and DCT in randomized order. All patients had a keratoconus which was assured by topography. In addition central corneal thickness (CCT) was measured with the Pentacam. For statistical analysis the Pearson correlation was calculated and a Bland-Altman diagram plotted. RESULTS: Mean corneal thickness was 486.2+/-45.5 microm. DCT measured the IOP at a mean value of 14.9+/-2.6 mmHg and GAT at 13.3+/-2.9 mmHg. With a mean difference of 1.6+/-2.4 mmHg DCT measured significantly higher than GAT (p