A Quality Improvement Project to Improve the Pathway and Outcomes for Patients with Necrotising Fasciitis.

Background: Necrotising fasciitis (NF) is a life-threatening illness that requires a multidisciplinary approach between surgeons in multiple specialties, intensivists, and microbiologists. Serial debridements and change of dressings are required prior to reconstruction. The aim of this study was to review the workload and streamline services in a tertiary centre for regional and internal referrals by formalizing an NF pathway agreed upon by all multidisciplinary team stakeholders and securing adequate resources for these complex patients. Methods: Retrospective data was collected on all patients with NF referred to the plastic surgery department between January 2017 and September 2018. Referrals were categorized as either regional (debridement had already taken place at another hospital) or internal (conducted on patients admitted through the emergency department). Results: A total of 41 patients (17 regional and 24 internal referrals) with a median age of 63 years (range, 28 to 85 years) were included in the study. Overall mortality rate was found to be 27%, median length of stay (LOS) amongst internal referrals was 25 days (range, 11 to 94 days), and median intensive care unit LOS was 8 days (range, 0 to 64 days). A total of 121 operations were conducted by 4 surgical specialties with a median time per procedure of 145 minutes (range, 50 to 605). 11 patients underwent reconstruction with split thickness graft and the median number of days between initial debridement to grafting was 13 (range, 2 to 38 days). Conclusions: Patients with NF require complex care and treatment. By characterizing and defining the workload involved in treating these patients, it may be possible to improve advanced planning and allocate resources accordingly to ensure that the centre runs as smoothly as possible without interruption to the acute trauma service.

Is the Quality of Mobile Health Applications for Burns Being Adequately Assessed?

High-quality mobile health applications (mHealth apps) have the potential to enhance the prevention, diagnosis, and treatment of burns. The primary aim of this study was to evaluate whether the quality of mHealth apps for burns care is being adequately assessed. The secondary aim was to determine whether these apps meet regulatory standards in the United Kingdom. We searched AMED, BNI, CINAHL, Cochrane Library, Embase, Emcare, Medline, and PsychInfo to identify studies assessing mHealth app quality for burns. The PRISMA reporting guideline was adhered to. Two independent reviewers screened abstracts to identify relevant studies. The quality of identified studies was assessed according to the framework proposed by Nouri et al, including design, information/content, usability, functionality, ethical issues, security/privacy, and user-perceived value. Of the 28 included studies, none assessed all seven domains of quality. Design was assessed in 4 of 28 studies; information/content in 26 of 28 studies; usability in 12 of 28 studies; functionality in 10 of 28 studies; ethical issues were never assessed in any studies; security/privacy was not assessed; subjective assessment was made in 9 of 28 studies. About 17 of 28 studies included apps that met the definition of "medical device" according to Medicines and Healthcare products Regulatory Agency guidance, yet only one app was appropriately certified with the UK Conformity Assessed mark. The quality of mHealth apps for burns is not being adequately assessed. The majority of apps should be considered medical devices according to UK standards, yet only one was appropriately certified. Regulatory bodies should support mHealth app developers, so as to improve quality control while simultaneously fostering innovation.

Can one stop nucleic acid sampling (OSNA) predict nodal positivity following neoadjuvant chemotherapy? A prospective cohort study of 293 patients.

Until recently, axillary node clearance had long been the standard of care in patients with axillary node-positive disease. One stop nucleic acid sampling (OSNA) has been used to guide intraoperative decision-making regarding suitability for axillary node clearance (ANC). The aim of this study is to evaluate the use of OSNA following neoadjuvant chemotherapy (NACT) and whether it can predict lymph node burden in ANC. A single center, prospective cohort study was performed on 297 patients having OSNA between 2016 and 2019. Patients were sub-classified according to node positivity at diagnosis and those treated with NACT and outcomes included copy number and lymph node harvest. Axillary complete pathological response was observed in 24/36 patients (67%) following NACT. 14/16 patients (87%) having axillary node clearance had axillary node disease limited to 4 nodes. OSNA copy numbers were significantly higher in patients showing disease progression following NACT. Overall, 73% of patients with lymph node positivity at diagnosis could be successfully treated with a combination of NACT and lymph node excision of four nodes. De-escalating axillary surgical treatment to resection of four nodes following NACT may be effective in balancing oncological resection and limiting treatment morbidity. ONSA can correctly identify patients experiencing disease progression who would benefit from traditional three-level ANC.

The Use of a Tetraminos Chimeric Free Flap in Lower Limb Trauma.

Major trauma care has improved in the UK since the evolution and acceptance of specialist centers . A mission statement for major trauma care is "reduction in mortality and disability following trauma." The care for extremity trauma has benefited from this specialization. Traumatic loss of skin integument in the extremities, especially over mobile joints, may lead to a compromised functional outcome. Modern reconstructive plastic surgery aims to provide flaps with minimal donor site morbidity. In this case report, we present the use of two chimeric flaps undertaken sequentially (one acutely and the second delayed) around the knee joint to allow a greater range of motion and function after a severe traumatic event. In this clinical case, the original tissue defects had meant that a free flap was used to reconstruct an open fractured bone, and split skin grafting was undertaken on the anterior aspect of the knee. The latter was then replaced after some months of recovery.

A Quality Improvement Project to Improve the Pathway and Outcomes for Patients with Necrotising Fasciitis.

Background: Necrotising fasciitis (NF) is a life-threatening illness that requires a multidisciplinary approach between surgeons in multiple specialties, intensivists, and microbiologists. Serial debridements and change of dressings are required prior to reconstruction. The aim of this study was to review the workload and streamline services in a tertiary centre for regional and internal referrals by formalizing an NF pathway agreed upon by all multidisciplinary team stakeholders and securing adequate resources for these complex patients. Methods: Retrospective data was collected on all patients with NF referred to the plastic surgery department between January 2017 and September 2018. Referrals were categorized as either regional (debridement had already taken place at another hospital) or internal (conducted on patients admitted through the emergency department). Results: A total of 41 patients (17 regional and 24 internal referrals) with a median age of 63 years (range, 28 to 85 years) were included in the study. Overall mortality rate was found to be 27%, median length of stay (LOS) amongst internal referrals was 25 days (range, 11 to 94 days), and median intensive care unit LOS was 8 days (range, 0 to 64 days). A total of 121 operations were conducted by 4 surgical specialties with a median time per procedure of 145 minutes (range, 50 to 605). 11 patients underwent reconstruction with split thickness graft and the median number of days between initial debridement to grafting was 13 (range, 2 to 38 days). Conclusions: Patients with NF require complex care and treatment. By characterizing and defining the workload involved in treating these patients, it may be possible to improve advanced planning and allocate resources accordingly to ensure that the centre runs as smoothly as possible without interruption to the acute trauma service.