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J Theor Biol
; 213(4): 547-57, 2001 Dec 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-11742524
RESUMEN
A general branching process model is developed to analyse familial dependence in longevity data. A general formula for the survival function of a randomly chosen sibling of an individual of a specified age is derived. The branching process model takes into account that siblings' ages may be censored. This is applied to a data set consisting of lifelengths of siblings of centenarians. Age distributions used in the branching process model are estimated from US Census data from the relevant period. It is demonstrated that there is a marked difference in the survival function according to the formula assuming no familial effect and the empirical survival function estimated from the data; thus, indicating a strong familial component.
Asunto(s)
Envejecimiento/genética , Modelos Genéticos , Adolescente , Adulto , Distribución por Edad , Anciano , Anciano de 80 o más Años , Niño , Genética de Población , Humanos , Tablas de Vida , Longevidad/genética , Persona de Mediana Edad , Dinámica Poblacional , Tasa de Supervivencia
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Cas Lek Cesk
; 125(11): 330-2, 1986 Mar 14.
Artículo
en Eslovaco
| MEDLINE
| ID: mdl-3955592