RESUMEN
Introduction: This study attempts to understand the demographics and salaries of the biosafety workforce worldwide. It builds upon previous surveys of biosafety professionals. Methods: Using multiple regression, this study explored what factors significantly predict salary. Moreover, this study examined whether significant differences existed regarding salary. These differences were analyzed in isolation (i.e., the variable itself) and while controlling for the variables that predicted salary. Results: In this article, eight factors significantly predicted salary: right-to-work state first, biosafety certifications, place of employment, data entry responsibilities, percentage of biosafety job responsibilities, number of direct reports, level of education, and finally the cumulative years of experience in the field. Discussion: This study highlighted certain trends that have remained consistent and new trends that have emerged over time. This research had increased international participation as compared with previous studies.
Asunto(s)
Infecciones Asintomáticas/epidemiología , COVID-19 , Control de Enfermedades Transmisibles , Transmisión de Enfermedad Infecciosa/prevención & control , Máscaras , SARS-CoV-2/aislamiento & purificación , COVID-19/diagnóstico , COVID-19/epidemiología , COVID-19/prevención & control , Control de Enfermedades Transmisibles/métodos , Control de Enfermedades Transmisibles/organización & administración , Trazado de Contacto/métodos , Trazado de Contacto/estadística & datos numéricos , Atención a la Salud/métodos , Atención a la Salud/estadística & datos numéricos , Personal de Salud/estadística & datos numéricos , Encuestas Epidemiológicas , Humanos , Incidencia , Máscaras/estadística & datos numéricos , Máscaras/provisión & distribución , North Carolina/epidemiologíaRESUMEN
BACKGROUND: Staphylococcus aureus is an important pathogen that forms biofilms. The global regulator sarA is essential for biofilm formation. Since the modulator of sarA (msa) is required for full expression of sarA and regulates several virulence factors, we examined the capacity of the msa mutant to form biofilm. RESULTS: We found that mutation of msa results in reduced expression of sarA in biofilm and that the msa mutant formed a weak and unstable biofilm. The msa mutant is able to adhere to surfaces and begins to form biofilm but fails to mature indicating that the defect of the msa mutant biofilm is in the accumulation stage but not in primary adhesion. CONCLUSION: The msa gene plays an important role in biofilm development which is likely due to its role in modulating the expression of sarA. This finding is significant because it identifies a new gene that plays a role in the development of biofilm.