Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 17 de 17
Filtrar
Más filtros










Base de datos
Intervalo de año de publicación
1.
Clin Nucl Med ; 49(4): 333-334, 2024 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-38377389

RESUMEN

ABSTRACT: Langerhans cell histiocytosis (LCH) is a rare hematological disease, more common in pediatric populations. A 26-year-old man with biopsy-proven cutaneous LCH underwent 18 F-FDG PET/CT systemic staging. 18 F-FDG PET/CT highlighted multiple sites of avid cutaneous disease within the natal cleft. Additional characteristic cystic lung disease was seen on the CT component and focal uptake in the pituitary stalk/hypothalamic region noted, a common but occult site of disease in this patient. Because of the rarity of adult-onset cutaneous LCH, guidance on management and staging is lacking. 18 F-FDG PET/CT is critical to baseline evaluation of systemic disease, as illustrated here.


Asunto(s)
Fluorodesoxiglucosa F18 , Neoplasias Cutáneas , Adulto , Masculino , Niño , Humanos , Tomografía Computarizada por Tomografía de Emisión de Positrones , Transporte Biológico , Biopsia
2.
Nucl Med Rev Cent East Eur ; 26(0): 153-155, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37991329

RESUMEN

A case involving a 64-year-old woman with ovarian carcinoma on maintenance therapy who underwent 18-fluorodeoxyglucose positron emission tomography with computed tomography ([18F]FDG PET/CT) restaging due to rapid cancer antigen 125 (Ca-125) rise. This revealed recurrent disease within the pelvis and large volume, peritoneal carcinomatosis including an avid umbilical deposit, consistent with the rarely seen Sister Mary Joseph nodule (SMJN). This case elegantly demonstrates not only the anatomy of the peritoneal surfaces through avid disease deposition but also highlights the sensitive depiction of disease burden in peritoneal carcinomatosis, including the detection of rare manifestations such as SMJN.


Asunto(s)
Carcinoma , Neoplasias Ováricas , Neoplasias Peritoneales , Nódulo de la Hermana María José , Femenino , Humanos , Persona de Mediana Edad , Tomografía Computarizada por Tomografía de Emisión de Positrones , Fluorodesoxiglucosa F18 , Neoplasias Peritoneales/diagnóstico por imagen , Tomografía de Emisión de Positrones/métodos , Neoplasias Ováricas/diagnóstico por imagen , Neoplasias Ováricas/patología , Nódulo de la Hermana María José/diagnóstico por imagen
3.
Indian J Nucl Med ; 38(4): 400-401, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-38390550

RESUMEN

Marginal zone lymphoma (MZL) is a group of low-grade, indolent, non-Hodgkin lymphomas rarely manifesting in the lungs. A 46-year-old man presenting with shortness of breath and cough was investigated and treated over 10 months for an atypical pattern of lung disease in keeping with cryptogenic organizing pneumonia (COP). Initial lung biopsies were nondiagnostic - repeat sampling eventually showed MZL. Staging whole-body (18F) fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) demonstrated multisystem stage IV disease with intensely avid widespread pulmonary changes resembling COP. The case elegantly illustrates that pulmonary MZL can present insidiously masquerading as COP and shows the value of (18F) FDG PET/CT to stage extranodal MZL.

4.
BJR Case Rep ; 8(3): 20210195, 2022 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-36101734

RESUMEN

Adult-onset Still's disease (AOSD) is an inflammatory disease of unknown aetiology, with no specific diagnostic tests. A 17-year-old female presented with fevers, night sweats and weight loss. Markedly FDG avid lymphadenopathy, and diffuse marrow and splenic uptake were demonstrated on [18F]FDG-PET/CT, most suggestive of lymphoma. After extensive investigations, the working diagnosis of AOSD was made. Other conditions, such AOSD, in addition to lymphoproliferative disorders, should be considered in the differential diagnosis of widespread avid lymphadenopathy in a teenager/young adult.

5.
Clin Nucl Med ; 47(8): 712-713, 2022 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-35384871

RESUMEN

ABSTRACT: In an attempt to protect the high-risk demographic and reduce burden on health care systems, concomitant administration of COVID-19 and influenza vaccines has been recommended by health bodies. The ComFluCOV trial indicates this is well tolerated with no reduction in immune response to either vaccine. A 48-year-old woman with right oropharyngeal squamous cell carcinoma underwent postradiotherapy FDG PET/CT, which demonstrated complete metabolic response. Incidental avid bilateral axillary lymphadenopathy of benign configuration was noted and concluded to be reactive in response to recent Pfizer-BioNTech booster and influenza vaccination. This is expected to be seen more frequently over the coming months.


Asunto(s)
COVID-19 , Gripe Humana , COVID-19/prevención & control , Femenino , Fluorodesoxiglucosa F18/metabolismo , Humanos , Gripe Humana/metabolismo , Gripe Humana/patología , Gripe Humana/prevención & control , Ganglios Linfáticos/patología , Persona de Mediana Edad , Tomografía Computarizada por Tomografía de Emisión de Positrones , Estaciones del Año , Vacunación
6.
Clin Nucl Med ; 47(3): e327-e328, 2022 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-35025792

RESUMEN

ABSTRACT: A 46-year-old woman with previous history of breast cancer had follow-up 18F-FDG PET/CT 5 days after COVID-19 vaccination. In addition to avid axillary nodes, a well-documented feature, the scan demonstrated diffuse splenic and marrow uptake. Clinical history, laboratory, and scan findings were in keeping with SIRS (systemic inflammatory response). The patient recovered with supportive management. On follow-up, 18F-FDG PET/CT imaging 3 months later features had resolved. SIRS after vaccination may be observed on 18F-FDG PET/CT.


Asunto(s)
COVID-19 , Fluorodesoxiglucosa F18 , Vacunas contra la COVID-19 , Femenino , Estudios de Seguimiento , Humanos , Inmunidad , Persona de Mediana Edad , Tomografía Computarizada por Tomografía de Emisión de Positrones , Tomografía de Emisión de Positrones , SARS-CoV-2 , Vacunación
7.
Clin Nucl Med ; 47(2): 166-167, 2022 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-34653048

RESUMEN

ABSTRACT: When interpreting an [18F]prostate specific membrane antigen (PSMA)-1007 PET/CT, it is important to understand the normal biodistribution of the tracer. A 73-year-old man with prostate cancer underwent [18F]PSMA-1007 PET/CT for biochemical recurrence. There was no abnormal uptake in the prostatectomy bed, but PSMA-avid pelvic nodal disease was found. Incidental intense focal uptake was also noted corresponding to the tip of the appendix, which was concluded to be physiological. This is an example of an uncommon site of physiological uptake of [18F]PSMA-1007 in the appendix.


Asunto(s)
Apéndice , Neoplasias de la Próstata , Anciano , Radioisótopos de Galio , Humanos , Masculino , Niacinamida/análogos & derivados , Oligopéptidos , Tomografía Computarizada por Tomografía de Emisión de Positrones , Prostatectomía , Neoplasias de la Próstata/cirugía , Distribución Tisular
8.
Clin Nucl Med ; 47(1): e89-e90, 2022 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-34269722

RESUMEN

ABSTRACT: The rapid rollout of COVID-19 vaccination is accompanied by incidental findings on 18F-FDG PET/CT. Most cases describe reactive axillary lymphadenopathy. A 46-year-old woman with previous history of stage 3A breast cancer underwent follow-up 18F-FDG PET/CT, which demonstrated avid left axillary nodes and intense diffuse splenic uptake and moderate diffuse bone marrow uptake. She had been administered COVID-19 vaccination in the left deltoid 1 week earlier and required hospitalization for 24 hours due to fever. Symptoms settled with supportive treatment. One month after the PET/CT scan, she remained well. Sites of uptake were taken to relate to a systemic immune response.


Asunto(s)
COVID-19 , Tomografía Computarizada por Tomografía de Emisión de Positrones , Vacunas contra la COVID-19 , Femenino , Fluorodesoxiglucosa F18 , Humanos , Inmunidad , Persona de Mediana Edad , SARS-CoV-2 , Vacunación
9.
Clin Nucl Med ; 46(12): 1016-1017, 2021 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-34115710

RESUMEN

ABSTRACT: A 70-year-old man with newly diagnosed prostate cancer underwent 18F-PSMA-1007 PET/CT for staging. PSMA-avid primary prostatic malignancy was identified. Incidental intense patchy peripheral lung uptake was also noted. The patient tested positive for COVID-19 infection.


Asunto(s)
COVID-19 , Neoplasias de la Próstata , Anciano , Ácido Edético , Humanos , Pulmón/patología , Masculino , Estadificación de Neoplasias , Niacinamida/análogos & derivados , Oligopéptidos , Tomografía Computarizada por Tomografía de Emisión de Positrones , Neoplasias de la Próstata/diagnóstico por imagen , Neoplasias de la Próstata/patología , SARS-CoV-2
10.
Clin Nucl Med ; 46(9): e461-e463, 2021 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-33883482

RESUMEN

ABSTRACT: According to published guidelines and routine procedures, patients are instructed to avoid strenuous exercise for 6 to 24 hours before FDG imaging, avoiding unfavorable muscular uptake. A 40-year-old man with esophageal carcinoma underwent FDG PET/CT for response assessment. Intense uptake was noted in the muscles of the right upper limb and chest. The patient stated he had avoided exercise before scanning. On further questioning, he was found to be a professional painter and decorator and had been working stripping wallpaper. Marked skeletal FDG uptake occurs in subjects who have strenuously exerted themselves before or after the injection of FDG.


Asunto(s)
Fluorodesoxiglucosa F18 , Tomografía Computarizada por Tomografía de Emisión de Positrones , Adulto , Fenómenos Biomecánicos , Humanos , Masculino , Radiofármacos , Extremidad Superior
11.
Clin Nucl Med ; 46(12): 1004-1005, 2021 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-33883486

RESUMEN

ABSTRACT: World-wide mass COVID-19 vaccination has been deployed starting with those most vulnerable, including the elderly and cancer patients. A 70-year-old man with right lung cancer underwent staging FDG PET/CT, which demonstrated an avid right lung mass with avid hilar and mediastinal nodes. Avid left axillary nodes of benign configuration were also noted. The patient had the Oxford-AstraZeneca COVID-19 vaccination in the left arm a week earlier. On reflection, the axillary nodes were concluded to be reactive related to this. This is a potential COVID-19 vaccination associated pitfall on PET/CT that should be considered when interpreting FDG PET/CT images.


Asunto(s)
COVID-19 , Tomografía Computarizada por Tomografía de Emisión de Positrones , Anciano , Vacunas contra la COVID-19 , Fluorodesoxiglucosa F18 , Humanos , Ganglios Linfáticos/diagnóstico por imagen , Masculino , Estadificación de Neoplasias , SARS-CoV-2 , Vacunación
14.
Clin Nucl Med ; 46(4): e221-e223, 2021 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-33234928

RESUMEN

ABSTRACT: In accordance with published international COVID-19 pandemic guidance (American College of Nuclear Medicine, British Nuclear Medicine Society, and European Association of Nuclear Medicine), the use of face masks has become an essential part of infection control for both patients and staff. A 56-year-old man with mantle cell lymphoma underwent staging FDG PET/CT, which demonstrated avid lymphadenopathy below the diaphragm and an unusual diffuse FDG uptake projected over the face, raising the suspicion of cutaneous lymphomatous involvement. On reflection of the clinical scenario and scanning conditions, cutaneous involvement was discounted; the pattern of uptake and lack of CT correlate were supportive of a cutaneous artifact related to the presence of the patient's mask.


Asunto(s)
COVID-19/prevención & control , Enfermedades de la Piel/diagnóstico por imagen , Artefactos , Fluorodesoxiglucosa F18 , Humanos , Control de Infecciones , Linfoma/diagnóstico por imagen , Masculino , Máscaras , Persona de Mediana Edad , Tomografía Computarizada por Tomografía de Emisión de Positrones , SARS-CoV-2
16.
Clin Nucl Med ; 46(2): e121-e122, 2021 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-32969909

RESUMEN

ABSTRACT: A 58-year-old man with previous melanoma of the left leg underwent whole-body 18F-FDG PET/CT to stage metastatic disease prior to commencing pembrolizumab. Follow-up FDG PET/CT after 3 months of treatment showed partial metabolic response of soft tissue and nodal metastases and diffuse increased thyroid and colonic uptake, suggestive of thyroiditis and colitis. Pembrolizumab was ceased, and a repeat FDG PET/CT scan showed regression of uptake in the thyroid gland and colon, in keeping with resolution of inflammatory change. Immune-related adverse events induced by Immune checkpoint inhibitors, such as pembrolizumab, should be recognized-cessation of treatment often leads to resolution.


Asunto(s)
Anticuerpos Monoclonales Humanizados/efectos adversos , Colitis/inducido químicamente , Colitis/diagnóstico por imagen , Fluorodesoxiglucosa F18 , Tomografía Computarizada por Tomografía de Emisión de Positrones , Tiroiditis/inducido químicamente , Tiroiditis/diagnóstico por imagen , Anticuerpos Monoclonales Humanizados/uso terapéutico , Humanos , Masculino , Melanoma/diagnóstico por imagen , Melanoma/tratamiento farmacológico , Persona de Mediana Edad
17.
Nucl Med Commun ; 39(2): 161-170, 2018 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-29300270

RESUMEN

PURPOSE: The purpose of this study was to compare the use of fluorine-18-fluorodeoxyglucose (F-FDG) PET with computed tomography (CT) and dynamic contrast-enhanced (DCE) MRI to predict prognosis and monitor treatment in malignant pleural mesothelioma. PATIENTS AND METHODS: F-FDG PET/CT and DCE-MRI studies carried out as part of the South West Area Mesothelioma Pemetrexed trial were used. F-FDG PET/CT and DCE-MRI studies were carried out before treatment, and after two cycles of chemotherapy, on patients treated with pemetrexed and cisplatin. A total of 73 patients were recruited, of whom 65 had PET/CT and DCE-MRI scans. Baseline measurements from F-FDG PET/CT (maximum standardized uptake value, metabolic tumour volume and total lesion glycolysis) and DCE-MRI (integrated area under the first 90s of the curve and washout slope) were compared with overall survival (OS) using Kaplan-Meier and Cox regression analyses, and changes in imaging measurements were compared with disease progression. RESULTS: PET/CT and DCE-MRI measurements were not correlated with each other. Maximum standardized uptake value, metabolic tumour volume and total lesion glycolysis were significantly related to OS with Cox regression analysis and Kaplan-Meir analysis, and DCE-MRI washout curve shape was significantly related to OS. DCE-MRI curve shape can be combined with F-FDG PET/CT to give additional prognostic information. Changes in measurements were not related to progression-free survival. CONCLUSIONS: F-FDG PET/CT and DCE-MRI give prognostic information in malignant pleural mesothelioma. Neither PET/CT nor DCE-MRI is useful for monitoring disease progression.


Asunto(s)
Medios de Contraste , Fluorodesoxiglucosa F18 , Neoplasias Pulmonares/diagnóstico por imagen , Imagen por Resonancia Magnética , Mesotelioma/diagnóstico por imagen , Tomografía Computarizada por Tomografía de Emisión de Positrones , Anciano , Anciano de 80 o más Años , Progresión de la Enfermedad , Femenino , Humanos , Procesamiento de Imagen Asistido por Computador , Neoplasias Pulmonares/tratamiento farmacológico , Neoplasias Pulmonares/patología , Masculino , Mesotelioma/tratamiento farmacológico , Mesotelioma/patología , Mesotelioma Maligno , Análisis de Supervivencia
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...