RESUMEN
Two experiments using a P300-enhanced Forced Choice Procedure (P3FCP) investigated simulated amnesia in a matching-to-sample task. In Experiment 1, successful manipulation of subjects towards different behavioral hit rates (75-80% vs. 85-90%) did not adversely affect the diagnostic sensitivity of match-mismatch Pz-P300 amplitude analyses, allowing detection of 69% of simulators. P300 amplitudes of simulators (Malinger group) were as large as those of truth-tellers (truth group, a control), indicating no dual task-related (Malingering) reduction across different behavioral hit rates. Experiment 2 found no main effect of oddball type, match vs. mismatch, on P300 (P3) amplitude with a mismatch-rare variant of the P3FCP. This study also revealed larger Pz-P3s in the Malingering (vs. Truth-telling) condition. Subsequent topographic analyses suggested different Truth and Malinger scaled P3 amplitude topographies in both these sets of P3FCP data and in those from a previous autobiographical memory paradigm. Further analysis yielded preliminary evidence for a common deception-related P3 amplitude topography across different paradigms/conditions.
Asunto(s)
Amnesia/fisiopatología , Amnesia/psicología , Potenciales Relacionados con Evento P300/fisiología , Detección de Mentiras/psicología , Simulación de Enfermedad/diagnóstico , Adulto , Conducta/fisiología , Humanos , Simulación de Enfermedad/fisiopatología , Cuero Cabelludo/anatomía & histologíaAsunto(s)
Dermatitis Exfoliativa/inducido químicamente , Medicamentos Herbarios Chinos/efectos adversos , Adulto , Dermatitis Exfoliativa/orina , Efedrina/análogos & derivados , Efedrina/orina , Femenino , Cromatografía de Gases y Espectrometría de Masas , Humanos , Fenilpropanolamina/orina , ComprimidosRESUMEN
The equipment, methods, logistics, and results of doping-control analyses for the 1984 Los Angeles Olympic Games are discussed in this article. Within 15 days, 1510 different urine specimens underwent 9440 screening analyses by a combination of gas chromatography, gas chromatography-mass spectrometry, "high-performance" liquid chromatography, and radioimmunoassay. These tests covered more than 200 different drugs and metabolites, including psychomotor stimulants, sympathomimetic amines, central nervous system stimulants, narcotic analgesics, and anabolic steroids. The results are summarized by class of drug. Less than 2% of the samples were found to contain a banned drug.