Bending not breaking: coping among Filipino University students experiencing psychological distress during the Global Health Crisis.

The impact of the global health crisis on students' mental health has been well documented. While most of the studies looked into the psychological impact of the coronavirus disease, the process of coping with psychological distress as experienced by university students in the Philippines remains unexamined. Cognizant of the dearth in literature, this grounded theory study purports to investigate and understand the coping processes among 20 Filipino university students. A comprehensive model highlights Filipino university students' coping techniques with psychological distress through vertical and horizontal analysis of the field text, open, axial, and selective coding. To ensure the trustworthiness and truthfulness of the theory and for refinement and consistency, triangulation, peer debriefing, and member checking validation strategies were likewise employed. The novel and distinct B.E.N.D. Model of Coping with Psychological Distress illustrates a substantive four-phased process symbolic of the challenges that a bamboo tree underwent, namely: (1) Befuddling Phase, (2) Enduring Phase, (3) Navigating Phase, and (4) Developing Phase. The phases that emerged had the advanced appreciable understanding of the university students' coping processes that may provide evidence-based information in crafting programs and specific interventions to support and safeguard students' mental health.

Portrait of Filipino healthcare workers' discrimination experiences during the early part of the COVID-19 pandemic.

BACKGROUND: At the core of a global health crisis, healthcare workers are tasked to perform crucial and life-threatening roles. Despite the heavy-laden responsibilities amid COVID-19 pandemic, these workers are subjected to various forms of stigma and discrimination. OBJECTIVES: The primary intent of this paper is to investigate the existence of discrimination among healthcare workers during COVID-19 pandemic in the Philippines. Further, it aims to test the following hypotheses: (1) Discrimination experiences among Filipino healthcare workers are dependent on certain demographic characteristics; and (2) Discrimination experiences vary significantly according to the type of healthcare workers. METHODS: This exploratory study used a two-part survey questionnaire consisting of the baseline data of the respondents and an 8-point Likert-type scale to identify the different forms of discrimination experienced by Filipino healthcare workers. Data yielded by the instruments were descriptively (frequency, mean and percentage) and inferentially (Pearson R, Kendall tau, t-test, and One-Way Analysis of Variance) treated. RESULTS: Among the Filipino healthcare workers, the Radiologic Technologists experienced the most forms of discriminatory acts, followed by Nurses and Medical Technologists. Those who work in high-risk duty assignments experienced the most discriminatory incidents such as insulting gestures and physical/social loathing, social media bashing and offensive jokes. CONCLUSION: The discrimination experienced by Filipino healthcare workers is a valuable platform for health policy interventions at the local and global levels to safeguard the physical, social and psychological well-being of healthcare workers, especially in battling the COVID-19 pandemic.

Perfil epidemiológico de los donadores de dientes humanos extraídos en establecimientos de salud pública, ubicados en Cuscatlán, La Paz y San Salvador, durante el año 2019 / Epidemiological profile of donors of human teeth extracted in public health facilities, located in Cuscatlán, La Paz and San Salvador, during the year 2019

Objetivo: Determinar el perfil epidemiológico de los donadores de dientes humanos en establecimientos de salud pública ubicados en Cuscatlán, La Paz y San Salvador durante el 2019. Metodología: Investigación observacional, descriptiva y transversal en 250 sujetos usuarios de cinco establecimientos de salud pública. Los instrumentos utilizados para la evaluación de las variables en estudio fueron cédula de entrevista para el registro de datos sociodemográficos e historia médica; para evaluar la condición bucal y características del diente extraído, una guía de observación. La información obtenida fue analizada en el programa SPSS, versión 25.0. Resultados: La población se concentró en los rangos de edades desde 21 a 50 años (58.8%), prevaleciendo el sexo femenino (64.0%), provenientes del área rural (56.80%). En la condición bucal, prevaleció la higiene bucal regular(35.60%); entre las entidades patológicas, las lesiones cariosas (78.0%),gingivitis/enfermedad periodontal (84.40%), abscesos (4.40%) y bruxismo(18.40%). Con respecto al motivo de extracción, el 48.40% fue por caries dental; 28.80%, enfermedad periodontal; 14.0%, razones ortodónticas. Los dientes extraídos con mayor frecuencia fueron con un 8.80% la 2-8, seguido del 8.0% por la 1-6 y con el 6.40% la 4-6. Conclusiones: La mayor cantidad de donadores de órganos dentales se encuentra en el grupo etario de 31 a 40 años, la mayoría pertenecientes al sexo femenino, provenientes del área rural. La principal causa de extracción de los órganos dentales recolectados fue caries dental y la tercera molar superior izquierda donada con mayor frecuencia.

To determine the epidemiological profile of human tooth donors in public health facilities located in Cuscatlán, La Paz and San Salvador during 2019. Methodology: Observational, descriptive and cross-cutting research in 250 subjects using five public health facilities. The instruments used for the evaluation of the variables under study were the interview cards for the recording sociodemographic data and medical history; To evaluate the oral condition and characteristics of the extracted tooth, an observation guide. The information obtained was analyzed in the SPSS program, version 25.0. Results: The population was concentrated on age ranges from 21 to 50 years (58.8%), prevailing the female gender (64.0%), coming from the rural area (56.80%). In the oral condition, regular oral hygiene prevailed (35.60%); Among the pathological entities, caries lesions (78.0%), gingivitis / periodontal disease (84.40%), abscesses (4.40%) bruxism (18.40%). With regard to the extraction site, 48.40% was tooth decay; 28.80%, periodontal disease; 14.0%, orthodontic reasons. The most frequently extracted teeth were with 8.80% 2-8, followed by 8.0% by 1-6 and 6.40% 4-6. Conclusions: The largest number of dental organ donors is found in the age group of 31 to 40 years, most of them female, from the rural area. The main cause of removal of the collected dental organs was tooth decay and the third most commonly donated upper left molar.

Randomized Controlled Trial to Evaluate an Internet-Based Self-Management Program in Systemic Sclerosis.

OBJECTIVE: In a pilot study, our group showed that an internet-based self-management program improves self-efficacy in systemic sclerosis (SSc). The objective of the current study was to compare an internet-based self-management program to a patient-focused educational book developed to assess measures of self-efficacy and other patient-reported outcomes in patients with SSc. METHODS: We conducted a 16-week randomized, controlled trial. RESULTS: Of the 267 participants who completed baseline questionnaires and were randomized to the intervention (internet: www.selfmanagescleroderma.com) or control (book) group, 123 participants (93%) in the internet group and 124 participants (94%) in the control group completed the 16-week randomized controlled trial (RCT). The mean ± SD age of all participants was 53.7 ± 11.7 years, 91% were women, and 79.4% had some college or a higher degree. The mean ± SD disease duration after diagnosis of SSc was 8.97 ± 8.50 years. There were no statistical differences between the 2 groups for the primary outcome measure (Patient-Reported Outcomes Measurement Information System Self-Efficacy for Managing Symptoms: mean change of 0.35 in the internet group versus 0.94 in the control group; P = 0.47) and secondary outcome measures, except the EuroQol 5-domain instrument visual analog scale score (P = 0.05). Internet group participants agreed that the self-management modules were of importance to them, the information was presented clearly, and the website was easy to use and at an appropriate reading level. CONCLUSION: Our RCT showed that the internet-based self-management website was not statistically superior to an educational patient-focused book in improving self-efficacy and other measures. The participants were enthusiastic about the content and presentation of the self-management website.

Inspection of the grapevine BURP superfamily highlights an expansion of RD22 genes with distinctive expression features in berry development and ABA-mediated stress responses.

The RESPONSIVE TO DEHYDRATION 22 (RD22) gene is a molecular link between abscisic acid (ABA) signalling and abiotic stress responses. Its expression has been used as a reliable ABA early response marker. In Arabidopsis, the single copy RD22 gene possesses a BURP domain also located at the C-terminus of USP embryonic proteins and the beta subunit of polygalacturonases. In grapevine, a RD22 gene has been identified but putative paralogs are also found in the grape genome, possibly forming a large RD22 family in this species. In this work, we searched for annotations containing BURP domains in the Vitis vinifera genome. Nineteen proteins were defined by a comparative analysis between the two genome predictions and RNA-Seq data. These sequences were compared to other plant BURPs identified in previous genome surveys allowing us to reconceive group classifications based on phylogenetic relationships and protein motif occurrence. We observed a lineage-specific evolution of the RD22 family, with the biggest expansion in grapevine and poplar. In contrast, rice, sorghum and maize presented highly expanded monocot-specific groups. The Vitis RD22 group may have expanded from segmental duplications as most of its members are confined to a region in chromosome 4. The inspection of transcriptomic data revealed variable expression of BURP genes in vegetative and reproductive organs. Many genes were induced in specific tissues or by abiotic and biotic stresses. Three RD22 genes were further studied showing that they responded oppositely to ABA and to stress conditions. Our results show that the inclusion of RNA-Seq data is essential while describing gene families and improving gene annotations. Robust phylogenetic analyses including all BURP members from other sequenced species helped us redefine previous relationships that were erroneously established. This work provides additional evidence for RD22 genes serving as marker genes for different organs or stresses in grapevine.

The predictive value of field versus arrival Glasgow Coma Scale score and TRISS calculations in moderate-to-severe traumatic brain injury.

BACKGROUND: Glasgow Coma Scale (GCS) scores are widely used to quantify level of consciousness in the prehospital environment. The predictive value of field versus arrival GCS is not well defined but has tremendous implications with regard to triage and therapeutic decisions as well as the use of various predictive scoring systems, such as Trauma Score and Injury Severity Score (TRISS). This study explores the predictive value of field GCS (fGCS) and arrival GCS (aGCS) as well as TRISS calculations using field (fTRISS) and arrival (aTRISS) data in patients with moderate-to-severe traumatic brain injury (TBI). METHODS: Major trauma victims with head Abbreviated Injury Scores of 3 or greater were identified from our county trauma registry over a 16-year period. The predictive ability of fGCS with regard to aGCS was explored using univariate statistics and linear regression modeling. The difference between aGCS and fGCS was also modeled against mortality and the composite endpoint using logistic regression, adjusting for fGCS. The predictive value of preadmission GCS (pGCS), defined as either fGCS or aGCS in nonintubated patients without a documented fGCS, with regard to mortality and a composite endpoint representing the need for neurosurgical care (death, craniotomy, invasive intracranial pressure monitoring, or intensive care unit care >48 hours) was determined using receiver-operator curve (ROC) analysis. Finally, fTRISS and aTRISS predicted survival values were compared with each other and to observed survival. RESULTS: A total of 12,882 patients were included. Mean values for fGCS and aGCS were similar (11.4 and 11.5, respectively, p = 0.336), and a strong correlation (r = 0.67, 95% CI 0.66-0.69, p < 0.0001) was observed between them. The difference between fGCS and aGCS was also predictive of outcome after adjusting for fGCS. Good predictive ability was observed for pGCS with regard to both mortality and neurosurgical intervention. Both fTRISS and aTRISS predicted survival values were nearly identical to observed survival. Observed and fTRISS predicted survival were nearly identical in patients undergoing prehospital intubation CONCLUSIONS: Values for fGCS are highly predictive of aGCS, and both are associated with outcome from TBI. A change in GCS from the field to arrival is highly predictive of outcome. The use of field data for TRISS calculations appears to be a valid methodological approach, even in severely injured TBI patients undergoing prehospital intubation.

The impact of aeromedical response to patients with moderate to severe traumatic brain injury.

STUDY OBJECTIVE: Aeromedical crews offer an advanced level of practice and rapid transport to definitive care; however, their efficacy remains unproven. Previous studies have used relatively small sample sizes or have been unable to adequately control for the effect of other potentially influential variables. Here we explore the impact of aeromedical response in patients with moderate to severe traumatic brain injury. METHODS: This was a retrospective analysis using our county trauma registry. All patients with head Abbreviated Injury Score of 3 or greater were included; interfacility transfers were excluded. The impact of aeromedical response was determined using logistic regression, adjusting for age, sex, mechanism, preadmission Glasgow Coma Scale score, head Abbreviated Injury Score, Injury Severity Score, and the presence of preadmission hypotension. Propensity scores were used to account for variability in selection of patients to undergo air versus ground transport. Patients with moderate and severe traumatic brain injury, as defined by head Abbreviated Injury Score and Glasgow Coma Scale score, were compared. Finally, aeromedical patients undergoing field intubation were compared with ground patients undergoing emergency department (ED) intubation. RESULTS: A total of 10,314 patients meeting all inclusion and exclusion criteria and with complete data sets were identified and included 3,017 transported by aeromedical crews. Overall mortality was 25% in the air- and ground-transported cohorts, but outcomes were significantly better for the aeromedical patients when adjusted for age, sex, mechanism of injury, hypotension, Glasgow Coma Scale score, head Abbreviated Injury Score, and Injury Severity Score (adjusted odds ratio [OR] 1.90; 95% confidence interval [CI] 1.60 to 2.25; P<.0001). Good outcomes (discharge to home, jail, psychiatric facility, rehabilitation, or leaving against medical advice) were also higher in aeromedical patients (adjusted OR 1.36; 95% CI 1.18 to 1.58; P<.0001). The primary benefit appeared to be in more severely injured patients, as reflected by head Abbreviated Injury Score and Glasgow Coma Scale score. Improved survival was also observed for air-transported patients intubated in the field versus ground-transported patients given emergency intubation in the ED (adjusted OR 1.42; 95% CI 1.13 to 1.78; P<.001). CONCLUSION: Here we analyze a large database of patients with moderate to severe traumatic brain injury. Aeromedical response appears to result in improved outcomes after adjustment for multiple influential factors in patients with moderate to severe traumatic brain injury. In addition, out-of-hospital intubation among air-transported patients resulted in better outcomes than ED intubation among ground-transported patients. Patients with more severe injuries appeared to derive the greatest benefit from aeromedical transport.