Correlation of nipple eczema in pregnancy with atopic dermatitis in Northern India: a study of 100 cases.

BACKGROUND: Nipple eczema is a less common presentation of atopic dermatitis. No studies in the literature have correlated nipple eczema in pregnancy as a manifestation of atopic dermatitis. OBJECTIVE: To evaluate whether nipple eczema presenting in pregnancy is a manifestation of atopic dermatitis. METHODS: This was a prospective observational study including 100 women who presented with nipple eczema for the first time during pregnancy. The exclusion criteria were any patient with previous history of nipple eczema, those already on oral or topical treatment for atopic dermatitis or nipple eczema, and other disorders mimicking eczema. Patients were divided into two groups ‒ nipple eczema with atopic dermatitis and without atopic dermatitis. Demographic data, clinical features, total leukocyte count, differential leukocyte count, absolute eosinophil counts, and serum IgE levels were compared between the two groups to detect association between nipple eczema in pregnancy and atopic dermatitis. RESULTS: Out of 100 patients, 39 were diagnosed with atopic dermatitis, whereas 61 were ruled out to have any features suggestive of atopic dermatitis. There were no statistically significant differences in mean age, mean duration of symptoms, and serum IgE levels. In patients with atopic dermatitis, bilateral symptoms were noted more commonly than in patients without the disease, but this was statistically insignificant. STUDY LIMITATIONS: Lack of long term follow-up and no large studies in literature to compare results. CONCLUSION: Nipple eczema in pregnancy follows a similar pattern as in other age groups. The clinical profile of patients is similar in cases with and without atopic dermatitis.

Correlation of nipple eczema in pregnancy with atopic dermatitis in Northern India: a study of 100 cases

Abstract Background Nipple eczema is a less common presentation of atopic dermatitis. No studies in the literature have correlated nipple eczema in pregnancy as a manifestation of atopic dermatitis. Objective To evaluate whether nipple eczema presenting in pregnancy is a manifestation of atopic dermatitis. Methods This was a prospective observational study including 100 women who presented with nipple eczema for the first time during pregnancy. The exclusion criteria were any patient with previous history of nipple eczema, those already on oral or topical treatment for atopic dermatitis or nipple eczema, and other disorders mimicking eczema. Patients were divided into two groups ‒ nipple eczema with atopic dermatitis and without atopic dermatitis. Demographic data, clinical features, total leukocyte count, differential leukocyte count, absolute eosinophil counts, and serum IgE levels were compared between the two groups to detect association between nipple eczema in pregnancy and atopic dermatitis. Results Out of 100 patients, 39 were diagnosed with atopic dermatitis, whereas 61 were ruled out to have any features suggestive of atopic dermatitis. There were no statistically significant differences in mean age, mean duration of symptoms, and serum IgE levels. In patients with atopic dermatitis, bilateral symptoms were noted more commonly than in patients without the disease, but this was statistically insignificant. Study limitations Lack of long term follow-up and no large studies in literature to compare results. Conclusion Nipple eczema in pregnancy follows a similar pattern as in other age groups. The clinical profile of patients is similar in cases with and without atopic dermatitis.

Comparative analysis of treatment of basicervical femur fractures in young adults with CCS, DHS, and PFN / Análise comparativa do tratamento de fraturas basocervicais de fêmur com CCS, DHS e PFN em adultos jovens

ABSTRACT Objective: To the best of the authors' knowledge, no studies in the literature have compared the clinical outcome of the three most common implants used to treat basicervical fractures of the femoral neck in young adults, i.e. CCS, DHS, and PFN. The present study attempts to fill the void in the literature and reach a conclusion regarding the usefulness of these implants in these fractures. Methods: This was a prospective interventional study including 90 patients with basicervical fracture of the neck of femur treated randomly with cancellous cannulated lag screws or dynamic hip screw, with a derotation screw or short PFN. Results: Mean time for fracture union was 14.4, 13.9, and 13.5 weeks and union rate was 93.2%, 100%, and 100% in groups 1, 2, and 3, respectively. The mean Harris Hip Score at the final follow up was similar among all the groups, i.e. 79.4, 82.2, and 81.9 in CCS, DHS, and PFN groups, respectively. The highest proportion of good to excellent results was noted in the DHS group, i.e. 83.3%, whereas it was 73.6% and 80% in the CCS and PFN groups, respectively. Conclusion: Multiple cancellous screws do not provide a sufficiently stable construct during fracture healing. PFN, although associated with lesser implant failures than CCS, have a higher incidence of technical errors. DHS provides sufficient stability in well-reduced basicervical fractures in young adults; it is associated with highest fracture union rates and best functional outcome out of the three implants at final follow-up.

RESUMO Objetivo: Tanto quanto é do conhecimento dos autores, nenhum estudo na literatura comparou o resultado clínico dos três implantes mais comumente usados para tratar fraturas basocervicais do colo femoral (CCS, DHS e PFN) em adultos jovens. O presente estudo tenta preencher essa lacuna na literatura e chegar a uma conclusão sobre a utilidade desses implantes nessas fraturas. Métodos: Estudo prospectivo de intervenção, incluiu 90 pacientes com fratura basocervical do colo femoral tratada aleatoriamente com parafuso esponjoso canulado interfragmentário ou parafuso de quadril dinâmico, com um parafuso derrotativo ou um PFN curto. Resultados: O tempo médio para a consolidação de fratura foi de 14,4, 13,9 e 13,5 semanas e a taxa de consolidação foi de 93,2%, 100% e 100% nos grupos 1, 2 e 3, respectivamente. A média do Harris Hip Score no seguimento final foi similar entre todos os grupos: 79,4, 82,2 e 81,9 nos grupos CCS, DHS e PFN, respectivamente. A maior proporção de resultados bons a excelentes foi observada no grupo DHS (83,3%), enquanto que foi de 73,6% e 80% nos grupos CCS e PFN, respectivamente. Conclusão: O uso de vários parafusos esponjosos não fornece uma construção suficientemente estável durante a consolidação da fratura. O PFN, embora associado a falhas de implantes menores do que o CCS, apresenta maior incidência de erros técnicos. O DHS proporciona estabilidade suficiente em fraturas basocervicais bem reduzidas em adultos jovens; seu uso está associado às maiores taxas de consolidação de fraturas e o melhor resultado funcional dentre os três implantes no seguimento final.

Comparative analysis of treatment of basicervical femur fractures in young adults with CCS, DHS, and PFN.

OBJECTIVE: To the best of the authors' knowledge, no studies in the literature have compared the clinical outcome of the three most common implants used to treat basicervical fractures of the femoral neck in young adults, i.e. CCS, DHS, and PFN. The present study attempts to fill the void in the literature and reach a conclusion regarding the usefulness of these implants in these fractures. METHODS: This was a prospective interventional study including 90 patients with basicervical fracture of the neck of femur treated randomly with cancellous cannulated lag screws or dynamic hip screw, with a derotation screw or short PFN. RESULTS: Mean time for fracture union was 14.4, 13.9, and 13.5 weeks and union rate was 93.2%, 100%, and 100% in groups 1, 2, and 3, respectively. The mean Harris Hip Score at the final follow up was similar among all the groups, i.e. 79.4, 82.2, and 81.9 in CCS, DHS, and PFN groups, respectively. The highest proportion of good to excellent results was noted in the DHS group, i.e. 83.3%, whereas it was 73.6% and 80% in the CCS and PFN groups, respectively. CONCLUSION: Multiple cancellous screws do not provide a sufficiently stable construct during fracture healing. PFN, although associated with lesser implant failures than CCS, have a higher incidence of technical errors. DHS provides sufficient stability in well-reduced basicervical fractures in young adults; it is associated with highest fracture union rates and best functional outcome out of the three implants at final follow-up.

OBJETIVO: Tanto quanto é do conhecimento dos autores, nenhum estudo na literatura comparou o resultado clínico dos três implantes mais comumente utilizados para tratar fraturas basocervicais do colo femoral (CCS, DHS e PFN) em adultos jovens. O presente estudo tenta preencher esta lacuna na literatura e chegar a uma conclusão sobre a utilidade desses implantes nessas fraturas. MÉTODOS: Estudo prospectivo de intervenção, incluindo 90 pacientes com fratura basocervical do colo femoral tratada aleatoriamente com parafuso esponjoso canulado interfragmentário ou parafuso de quadril dinâmico, com um parafuso derrotativo ou um PFN curto. RESULTADOS: O tempo médio para a consolidação de fratura foi de 14,4, 13,9 e 13,5 semanas e a taxa de consolidação foi de 93,2%, 100% e 100% nos grupos 1, 2 e 3, respectivamente. A média do Harris Hip Score no seguimento final foi similar entre todos os grupos: 79,4, 82,2 e 81,9 nos grupos CCS, DHS e PFN, respectivamente. A maior proporção de resultados bons a excelentes foi observada no grupo DHS (83,3%), enquanto que foi de 73,6% e 80% nos grupos CCS e PFN, respectivamente. CONCLUSÃO: O uso de vários parafusos esponjosos não fornece uma construção suficientemente estável durante a consolidação da fratura. O PFN, embora associado a falhas de implantes menores do que o CCS, apresenta maior incidência de erros técnicos. O DHS proporciona estabilidade suficiente em fraturas basocervicais bem reduzidas em adultos jovens; seu uso está associado às maiores taxas de consolidação de fraturas e o melhor resultado funcional dentre os três implantes no seguimento final.

Treatment of stable intertrochanteric fractures of the femur with proximal femoral nail versus dynamic hip screw: a comparative study / Tratamento de fraturas intertrocantéricas estáveis do fêmur com haste femoral proximal versus parafuso dinâmico de quadril: um estudo comparativo

ABSTRACT Objective: To evaluate and compare the clinical and radiological outcomes of patients with stable intertrochanteric fractures treated with proximal femoral nail vs. dynamic hip screw. Methods: Sixty patients with stable intertrochanteric fractures, aged over 18 years, were randomly divided into the proximal femoral nail and dynamic hip screw groups. Dynamic hip screw with a three-hole side-plate and an anti-rotation screw were used, as well as a modified ultra-short proximal femoral nail for the smaller Asian population. The intra-operative, early and late complications were recorded, and the functional outcome of each group was assessed using the Harris Hip Score. Results: In the dynamic hip screw group, the one-month mean Harris Hip Score was slightly lower than that of the proximal femoral nail group. However, at the three- and six-month monthly follow-ups, the dynamic hip screw group presented higher mean scores than the proximal femoral nail group; at the one-year follow-up, both the groups attained similar scores. Conclusion: Proximal femoral nail provides a significantly shorter surgery with a smaller incision that leads to less wound-related complications. However, the incidence of technical errors was significantly higher in proximal femoral nail when compared with dynamic hip screw as it is a technically more demanding surgery that leads to more implant failures and the consequent re-operations.

RESUMO Objetivo: Avaliar e comparar os resultados clínicos e radiológicos de pacientes com fraturas intertrocantéricas estáveis tratados com hastes femorais proximais vs. parafuso dinâmico de quadril. Métodos: Sessenta pacientes com fraturas intertrocantéricas estáveis, maiores de 18 anos, foram divididos aleatoriamente em dois grupos, um de hastes femorais proximais e outro de parafuso dinâmico de quadril. Um parafuso dinâmico de quadril com placa lateral de três furos e um parafuso antirrotação foram usados, bem como uma hastes femorais proximais ultracurtas, modificadas para a população asiática de menor estatura. As complicações intraoperatórias, precoces e tardias foram registradas; o resultado funcional de cada grupo foi avaliado com o Harris Hip Score. Resultados: No grupo parafuso dinâmico de quadril, o Harris Hip Score foi um pouco menor do que o do grupo hastes femorais proximais. Entretanto, nos seguimentos de três e seis meses, o grupo parafuso dinâmico de quadril apresentou maior média do que o grupo hastes femorais proximais; no seguimento de um ano, ambos os grupos atingiram valores similares. Conclusão: A hastes femorais proximais proporcionam uma cirurgia significativamente mais curta, com uma menor incisão e consequentemente menos complicações relacionadas à ferida. Entretanto, a incidência de erros técnicos foi significativamente maior no grupo hastes femorais proximais quando comparada com o grupo parafuso dinâmico de quadril, visto que essa é uma cirurgia tecnicamente mais exigente, que apresenta mais falhas de implantes e as consequentes reoperações.

Treatment of stable intertrochanteric fractures of the femur with proximal femoral nail versus dynamic hip screw: a comparative study.

OBJECTIVE: To evaluate and compare the clinical and radiological outcomes of patients with stable intertrochanteric fractures treated with proximal femoral nail vs. dynamic hip screw. METHODS: Sixty patients with stable intertrochanteric fractures, aged over 18 years, were randomly divided into the proximal femoral nail and dynamic hip screw groups. Dynamic hip screw with a three-hole side-plate and an anti-rotation screw were used, as well as a modified ultra-short proximal femoral nail for the smaller Asian population. The intra-operative, early and late complications were recorded, and the functional outcome of each group was assessed using the Harris Hip Score. RESULTS: In the dynamic hip screw group, the one-month mean Harris Hip Score was slightly lower than that of the proximal femoral nail group. However, at the three- and six-month monthly follow-ups, the dynamic hip screw group presented higher mean scores than the proximal femoral nail group; at the one-year follow-up, both the groups attained similar scores. CONCLUSION: Proximal femoral nail provides a significantly shorter surgery with a smaller incision that leads to less wound-related complications. However, the incidence of technical errors was significantly higher in proximal femoral nail when compared with dynamic hip screw as it is a technically more demanding surgery that leads to more implant failures and the consequent re-operations.

OBJETIVO: Avaliar e comparar os resultados clínicos e radiológicos de pacientes com fraturas intertrocantéricas estáveis tratados com hastes femorais proximais vs. parafuso dinâmico de quadril. MÉTODOS: Sessenta pacientes com fraturas intertrocantéricas estáveis, maiores de 18 anos, foram divididos aleatoriamente em dois grupos, um grupo de hastes femorais proximais e outro grupo de parafuso dinâmico de quadril. Um parafuso dinâmico de quadril com placa lateral de três furos e um parafuso antirotação foram utilizados, bem como uma hastes femorais proximais ultracurtas, modificadas para a população asiática de menor estatura. As complicações intraoperatórias, precoces e tardias foram registradas; o resultado funcional de cada grupo foi avaliado usando o Harris Hip Score. RESULTADOS: No grupo parafuso dinâmico de quadril, o Harris Hip Score foi um pouco menor do que o do grupo hastes femorais proximais. Entretanto, nos seguimentos de três e seis meses, o grupo parafuso dinâmico de quadril apresentou maior média do que o grupo hastes femorais proximais; no seguimento de um ano, ambos os grupos atingiram valores similares. CONCLUSÃO: A hastes femorais proximais proporciona uma cirurgia significativamente mais curta, com uma menor incisão e consequentemente menos complicações relacionadas à ferida. Entretanto, a incidência de erros técnicos foi significativamente maior no grupo hastes femorais proximais quando comparada ao grupo parafuso dinâmico de quadril visto que esta é uma cirurgia tecnicamente mais exigente, que apresenta mais falhas de implantes e as consequentes reoperações.

Clinico-epidemiological profile of patients attending Suraksha Clinic of tertiary care hospital of North India.

BACKGROUND: Sexually transmitted infections (STIs) are a global health problem. Trends of STIs vary from place to place depending on various epidemiological factors prevailing in that respective geographic area. AIMS AND OBJECTIVES: The present study was conducted to find the pattern and prevalence of different STIs out of total STI clinic attendees, to identify any change in the trend of STIs, various epidemiological factors, and behavior of individual diseases. MATERIALS AND METHODS: Case records of the patients, attending the STI clinic (Suraksha Clinic) attached with Department of Dermatology, Venereology, and Leprosy of a tertiary care medical college and hospital of North India from April 2007 to March 2014, were analyzed. All the patients were thoroughly examined and investigated. RESULTS: This study included a total of 5468 STI clinic attendees out of which 3908 were diagnosed to have STIs. Most of the patients were male, married, and in the third decade of their lives. In our study, the highest number of patients had herpes genitalis, i.e., 850 patients (21.75%) followed by 415 patients (10.61%) having genital warts. Molluscum contagiosum was present in 239 patients (6.11%), 106 patients (2.71%) had urethral discharge whereas 81 patients (2.07%) diagnosed to have syphilis. Viral infections accounted for 38.48% of cases. Human immunodeficiency virus (HIV) positivity was seen in 414 patients (10.59%) of total STI cases. CONCLUSION: The trend of STIs is changing from bacterial to viral diseases. This is because of the widespread use of antibacterial, self-medication, and treatment through national program. STIs enhance the susceptibility of an individual to acquire or transmit HIV through sexual contact.

Moisturizers: The Slippery Road.

Moisturizers are an important part of a dermatologist's armamentarium although little is written and well, a less is truly known about them. There is a cornucopia of projected skin products in the market whose real scientific role is not proven. These products although at times are regarded as mere cosmetics but have a well-known role in many skin disorders. Adequate knowledge about their mechanism of action, dosage, usage, and adverse effects is must for a dermatologist in this era. This article aims to bring forth the ever hidden facts of the much-hyped moisturizers. It is probably the first of its kind covering all aspects of moisturizers ranging from basic science to clinical usage, a subject that receives a short shrift in the current dermatological text.

Mal de Meleda with Congenital Cataract: A Novel Case Report.

Mal de meleda (MdM), a rare autosomal recessive genodermatosis is characterized by erythema and hyperkeratosis of the palms and soles with a sharp demarcation and that progress with age (progrediens) and extend to the dorsal aspects of the hands and feet (transgrediens). It has been associated with various conditions albeit rarely with congenial cataract. Ocular lens and the skin have the same embryological origins. We hereby present this novel case report of Mal de meleda in association with congenital posterior subcapsular cataract which to the best of our knowledge has not been reported from India before.

Phacomatosis cesiomarmorata with hypospadias and phacomatosis cesioflammea with Sturge-Weber syndrome, Klippel-Trenaunay syndrome and aplasia of veins -- case reports with rare associations.

Phacomatosis pigmentovascularis (PPV) is a rare genodermatosis characterized by the co-existence of an extensive vascular and a pigmentary nevus with or without extracutaneous manifestations. We report two such rare cases. The first is a 3-year-old boy exhibiting a rare association of cutis marmorata telangiectatica congenita with aberrant dermal melanocytosis along with hypospadias and melanosis oculi (traditionally classified as PPV type Vb or phacomatosis cesiomarmorata - Happle's classification). The other patient is a 5-year-old boy with Sturge-Weber syndrome, Klippel-Trenaunay syndrome, aplasia of iliac, femoral, and popliteal veins and congenital heart disease, associated with aberrant dermal melanocytosis and melanosis oculi (also classified as PPV type IIb or phacomatosis cesioflammea). These sporadic cases display a unique constellation of additional, previously unreported systemic associations, which will further expand the clinical spectrum of phacomatosis pigmentovascularis.