Exceptionally rare cause of a total stomach resection.

The first-ever case of a 54-year-old woman who overdosed on non-steroidal anti-inflammatory drugs in an attempt at suicide. Before that incident, she had not been treated for coexisting diseases such as rheumatoid arthritis or depression. At the time of admission to the General Surgery Department, the patient reported pains in the epigastric region with accompanying nausea and vomiting with mucous content as well as the inability to ingest food orally. Despite parenteral and enteral feeding, the patient exhibited a drop in body mass. The histopathologic examination of a sample taken from the stomach during gastroscopy showed some non-specific necrotic and inflammatory masses with granulation. Intraoperatively, a very small, infiltrated stomach with an initial section of duodenum was identified. A total stomach resection together with the reconstruction of digestive tract continuity was performed using the Roux-Y method. Histopathologic examination of the stomach revealed a deep, chronic and exacerbated inflammatory condition with an extensive ulceration over the entire length of the stomach, reaching up to the pylorus. Additionally, numerous lymphatic glands with inflammatory reaction changes were observed.

The effect of nutritional habits and addictions on the incidence of thyroid carcinoma in the Olsztyn province of Poland.

INTRODUCTION: The aim of this study was to investigate the roles of nutritional habits and addictions in the incidence of thyroid carcinoma. MATERIAL AND METHODS: The study of risk factors affecting the incidence of thyroid carcinoma was conducted in patients included in a register of thyroid carcinoma. For that purpose, a questionnaire was prepared. The questionnaire covered: personal information, medical history, individual risk factors of thyroid carcinoma such as nutritional habits, alcohol consumption and smoking. Statistical analysis was conducted. RESULTS: The register comprised 297 patients with thyroid carcinoma (89% women) and 589 healthy subjects. 46% of patients declared frequent consumption of milk and dairy products. The patients with thyroid carcinoma consumed cruciferous plants significantly more often than healthy subjects (p = 0.0001) whereas egg consumption among both groups of patients was similar. Low consumption of fish and average table salt consumption was typical of both groups. Alcohol consumption was similar in both groups and was, respectively, 42.18% and 47.59%. The patients with thyroid cancer smoked less frequently than subjects from the control group. Logistic regression analysis showed that carcinoma risk increased in patients who consumed cruciferous vegetables (brassicas). Their regular intake was related to a 1.5-fold (CI 1.19-1.96) higher risk of thyroid carcinoma incidence. Despite the demonstrated decreased risk of thyroid cancer, smoking (OR 0.54) was not considered a protective factor. CONCLUSIONS: 1. It is not possible to determine unequivocally the causative factors for the growth in the incidence of thyroid cancer in Olsztyn province. 2. It appears that one of the environmental factors causing the increase is overconsumption of cruciferous vegetables.

Effect of individual and socio-economic risk factors on the incidence of thyroid carcinoma in Olsztyn province.

INTRODUCTION: The aim of this study was an investigation into the individual and socio-economic risk factors of the incidence of thyroid carcinoma. MATERIAL AND METHODS: Our study was into risk factors affecting the incidence of thyroid carcinoma conducted in patients included in a register of thyroid carcinoma. For that purpose, a questionnaire was prepared which covered personal information, medical history and socio-economic factors. A statistical analysis was conducted. RESULTS: The register comprised 297 patients (89% female) with thyroid carcinoma and 589 healthy subjects. Age group distribution was similar for both groups. The largest group was aged 50-54. The number of children born to women with carcinoma and women in the control group did not differ significantly. 10% of the women with carcinoma had used contraception. Patients were most frequently born in Olsztyn province, an area of relative iodine deficiency. 9.72% had suffered from thyroid disease in childhood. 32.41% had a family history of thyroid disease. Mothers of patients most frequently also came from regions of similar iodine level. The fathers most frequently came from Warsaw province (17.08%). The origin of the remainder was the same as of the mothers. 36% of patients had elementary, 14% vocational, 38% secondary and 13% higher education. Logistic regression showed that the risk of carcinoma increased 0.98 times in each person younger by a year. Individuals with body mass lower had 0.98 times greater risk of the disease by each kilogram. CONCLUSIONS: The risk factors for the incidence of thyroid carcinoma: female sex, age at onset, low body mass.

Did the Chernobyl atomic plant accident have an influence on the incidence of thyroid carcinoma in the province of Olsztyn?

MATERIAL AND METHODS: A study of incidence rates of thyroid carcinoma was conducted in Olsztyn province from 1 January 1994 to 31 December 2003 within its former boundaries, in spite of Poland's new administrative division. The criteria for register entry were as follows: residence in Olsztyn province, newly-diagnosed case of thyroid malignancy in the given calendar year, and histopathological verification in the Department of Anatomical Pathology of the District Specialist Hospital in Olsztyn. The study of selected risk factors comprised patients included in the register of thyroid carcinoma. For that purpose a questionnaire was prepared which covered information about the Chernobyl accident: place of residence, time of carcinoma diagnosis after the accident, and iodine prophylaxis during the accident. The control group consisted of 589 healthy subjects selected based on age and place of residence. RESULTS: In the years 1993-2003, 462 (395 women and 67 men) cases of thyroid cancer were registered. The questionnaire study comprised 297 patients with thyroid carcinoma and 589 healthy subjects. Study subjects from both the affected and control groups stayed mainly in their place of residence during the Chernobyl accident (97.28% v. 94.24%). Thyroid carcinoma was diagnosed on average 13.58 ± 2.61 years after irradiation. There were no significant differences in iodine prophylaxis during the Chernobyl accident. Lugol's solution was given to 31% of patients and 34% of healthy respondents. CONCLUSIONS: 1. It cannot be stated that the Chernobyl disaster had any influence on the incidence rate of thyroid carcinoma in the province of Olsztyn. 2. Iodine prophylaxis using Lugol's solution could have an influence on lack of significant increase of the thyroid carcinoma incidence rate in the age group 1-18 years.