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Introduction: Baló's concentric sclerosis (BCS) is a rare subtype of multiple sclerosis characterized by inflammatory demyelination within the central nervous system. Case Presentation: This case report presents a challenging diagnostic scenario involving a 26-year-old woman diagnosed with BCS. Despite treatment, her condition did not ameliorate, and magnetic resonance imaging (MRI) findings remained unchanged. A subsequent stereotactic biopsy revealed tumefactive Balo disease, highlighting the intricate diagnostic and therapeutic issues surrounding BCS. Conclusion: The juxtacortical location of the BCS lesion, as observed in our case, suggests an unfavourable prognosis due to treatment-resistant seizures.
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According to several studies, children represent only about 2% of the patients affected by the current SARS-CoV-2, and most often, they are asymptomatic. However, there is a concern about a vascular inflammatory disease which is similar to Kawasaki disease observed in children and adolescents weeks after infection. We report a case of Kawasaki disease presented with ischemic stroke in a 14-year-old male patient following SARS-Cov-2 infection.
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PURPOSE: Despite the common occurrence of early seizures (ES) after stroke, the relationship between risk factors and this complication of stroke is not well established. In this study we have examined the relationship between clinical measures on admission and ES after stroke. METHODS: We included 1073 patients (mean age 69 ± 12, 51.6% females) with ischemic and haemorrhagic stroke. The frequency of seizure occurrence within 2 weeks of stroke was determined. We used a logistic regression model to analyse the effect of blood pressure on admission and other clinical factors (age, gender, diabetes, atrial fibrillation and dyslipidemia) on the occurrence of ES after stroke. RESULTS: ES occurred after 4.1% and 4.0% of ischemic and haemorrhagic strokes respectively. Compared to patients with high blood pressure on admission, those with low and normal blood pressure had a higher risk of ES after stroke (2.9% vs.7.5% vs. 7.6%, p=0.001). Also the mean age of patients with post-stroke ES was lower (62.5 vs. 69.3, p<0.001). In a logistic regression analysis, low/normal blood pressure remained independently associated with ES after stroke with OR of 2.46 (95% CI 1.38-4.63, p=0.006). CONCLUSION: ES after stroke was equally frequent in patients with ischemic and haemorrhagic stroke. Low/normal blood pressure on admission and younger patient age were risk factors for ES after stroke.