Prognosis of laparoscopic surgery for colorectal cancer in middle-aged patients.

Background: The prognosis of middle-aged patients with colorectal cancer (CRC) treated by laparoscopic resection (LR) is unclear. This study aimed to evaluate the survival outcomes of LR compared with open resection (OR) for middle-aged patients with CRC. Patients and Methods: This retrospective cohort study used the data from a database of all consecutive colorectal resections performed between January 2009 and December 2017. Propensity score matching (PSM) was performed to handle the selection bias based on age, gender, body mass index, tumour location, AJCC stage and admission year. Univariate and multivariate COX regression model was used to identify risk factors of overall survival (OS) and disease-free survival (DFS). Results: After PSM, 154 patients were included in each group. Compared with the OR group in the total cohort, there were better survival outcomes in the LR group for 5-year OS and 5-year DFS (both P < 0.001). These differences were observed for Stage II and III diseases and for all CRC, irrespective of location. The multivariate analysis showed that tumour ≥5 cm (hazard ratio [HR] = 1.750, 95% confidence interval [CI]: 1.026-2.986, P = 0.040), Stage III (HR = 14.092, 95% CI: 1.894-104.848, P = 0.010) and LR (HR = 0.300, 95% CI: 0.160-0.560, P < 0.001) were independently associated with OS. Pre-operative carcinoembryonic antigen ≥5 ng/ml (HR = 3.954, 95% CI: 1.363-11.473, P = 0.011), Stage III (HR = 6.206, 95% CI: 1.470-26.200, P = 0.013) and LR (HR = 0.341, 95% CI: 0.178-0.653, P = 0.001) were independently associated with DFS. Conclusions: In middle-aged patients with CRC, LR achieves better survival than OR. Complications are similar, except for less blood loss and shorter post-surgical hospital stay with LR.

[Application of Goethite Modified Biochar for Arsenic Removal from Aqueous Solution].

To improve the adsorption capacity of wheat biochar (BC) for arsenic (As), wheat stalks were selected as biomass to generate nano-sized goethite modified biochar (Goethite@BC) by co-precipitation. The adsorption capacities of BC, Goethite, and Goethite@BC for As(Ⅲ) were compared. The samples were analyzed by scanning electron microscopy (SEM) along with energy dispersive spectrometry (EDS), Brunauer-Emmett-Teller (BET), Fourier transform infrared (FT-IR), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS) techniques. The results showed that the nano-goethite coating was uniformly attached to the surface of the BC and improved the surface area and total pore volume of the biochar. The adsorption of As(Ⅲ) by the three adsorbents was proved to fit well with the pseudo-second-order kinetic model and the Langmuir model. Compared to BC, the Goethite@BC increased the adsorption rate of As(Ⅲ) by 62.10 times, and the maximum adsorption capacity of Goethite@BC was 65.20 mg·g-1. The adsorption mechanism of Goethite@BC included non-specific adsorption (electrostatic attraction) and specific adsorption (coordination, complexation, ion exchange, etc.), and nano-goethite particles on the Goethite@BC surface played an important role in the adsorption of As. Goethite@BC has a good application prospects in the field of environmental remediation.