1.
Chem Commun (Camb)
; 52(21): 4041-4, 2016 Mar 14.
Artículo
en Inglés
| MEDLINE
| ID: mdl-26891088
RESUMEN
We developed a light-up fluorophore-DNA aptamer pair for label-free aptamer sensors that fluoresce upon binding to the analyte. A 42mer DNA aptamer binding to the environment-sensitive fluorophore, dapoxyl, which increased the fluorescence by more than 700-fold upon binding, was successfully used to construct aptamer sensors by fusion with analyte-binding DNA aptamers.