1.
DICP
; 25(6): 598-600, 1991 Jun.
Artículo
en Inglés
| MEDLINE
| ID: mdl-1877267
RESUMEN
Patients who are receiving multiple medications must be screened for significant drug interactions. The specific mechanism of a drug interaction determines whether the patient may experience a subtherapeutic effect or a potentially toxic reaction. Three cases of relative warfarin resistance, possibly related to high-dose nafcillin, are described in this report. Several reports have suggested that penicillinase-resistant penicillins, such as nafcillin and dicloxacillin, exert an important enzyme-inducing effect in patients receiving warfarin. This potential interaction must be appropriately recognized and managed in order to maintain adequate anticoagulation in this patient population.
Asunto(s)
Hipoprotrombinemias/inducido químicamente , Nafcilina/administración & dosificación , Warfarina/administración & dosificación , Anciano , Interacciones Farmacológicas , Humanos , Masculino , Persona de Mediana Edad , Nafcilina/efectos adversos , Warfarina/efectos adversos
2.
Am J Hosp Pharm
; 46(8): 1547-8, 1989 Aug.
Artículo
en Inglés
| MEDLINE
| ID: mdl-2773954
3.
Drug Intell Clin Pharm
; 22(5): 425, 1988 May.
Artículo
en Inglés
| MEDLINE
| ID: mdl-3391114
4.
Am J Hosp Pharm
; 45(5): 1111-3, 1988 May.
Artículo
en Inglés
| MEDLINE
| ID: mdl-3400654