1.
Biochem Genet
; 13(9-10): 533-50, 1975 Oct.
Artículo
en Inglés
| MEDLINE
| ID: mdl-1239275
RESUMEN
Comparative immunochemical analysis of ceruloplasmin-synthesizing polyribosomes in liver biopsies from control subjects and homozygous carriers of the Wilson's mutation was performed. According to I125-antibody binding data, the amount of ceruloplasmin-forming liver polysomes in patients with Wilson's disease was 10--20 times lower than that in non-Wilson patients. Correspondingly, the pulse labeling of ceruloplasmin polypeptides was decreased several-fold in the cell-free liver preparations from patients with Wilson's disease.
Asunto(s)
Ceruloplasmina/biosíntesis , Degeneración Hepatolenticular/metabolismo , Hígado/metabolismo , Polirribosomas/metabolismo , Aminoácidos/metabolismo , Animales , Especificidad de Anticuerpos , Sistema Libre de Células , Ceruloplasmina/inmunología , Degeneración Hepatolenticular/inmunología , Homocigoto , Humanos , Conejos
2.
Experientia
; 25(4): 424-6, 1969 Apr 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-4979093