Demonstration of Scale-Invariant Rayleigh-Taylor Instability Growth in Laser-Driven Cylindrical Implosion Experiments.

Rayleigh-Taylor instability growth is shown to be hydrodynamically scale invariant in convergent cylindrical implosions for targets that varied in radial dimension and implosion timescale by a factor of 3. The targets were driven directly by laser irradiation providing a short impulse, and instability growth at an embedded aluminum interface occurs as it converges radially inward by a factor of 2.25 and decelerates on a central foam core. Late-time growth factors of 14 are observed for a single-mode m=20 azimuthal perturbation at both scales, despite the differences in laser drive conditions between the experimental facilities, consistent with predictions from radiation-hydrodynamics simulations. This platform enables detailed investigations into the limits of hydrodynamic scaling in high-energy-density systems.

Self-Similar Multimode Bubble-Front Evolution of the Ablative Rayleigh-Taylor Instability in Two and Three Dimensions.

The self-similar nonlinear evolution of the multimode ablative Rayleigh-Taylor instability (ARTI) is studied numerically in both two and three dimensions. It is shown that the nonlinear multimode bubble-front penetration follows the α_{b}A_{T}(∫sqrt[g]dt)^{2} scaling law with α_{b} dependent on the initial conditions and ablation velocity. The value of α_{b} is determined by the bubble competition theory, indicating that mass ablation reduces α_{b} with respect to the classical value for the same initial perturbation amplitude. It is also shown that ablation-driven vorticity accelerates the bubble velocity and prevents the transition from the bubble competition to the bubble merger regime at large initial amplitudes leading to higher α_{b} than in the classical case. Because of the dependence of α_{b} on initial perturbation and vorticity generation, ablative stabilization of the nonlinear ARTI is not as effective as previously anticipated for large initial perturbations.

How high energy fluxes may affect Rayleigh-Taylor instability growth in young supernova remnants.

Energy-transport effects can alter the structure that develops as a supernova evolves into a supernova remnant. The Rayleigh-Taylor instability is thought to produce structure at the interface between the stellar ejecta and the circumstellar matter, based on simple models and hydrodynamic simulations. Here we report experimental results from the National Ignition Facility to explore how large energy fluxes, which are present in supernovae, affect this structure. We observed a reduction in Rayleigh-Taylor growth. In analyzing the comparison with supernova SN1993J, a Type II supernova, we found that the energy fluxes produced by heat conduction appear to be larger than the radiative energy fluxes, and large enough to have dramatic consequences. No reported astrophysical simulations have included radiation and heat conduction self-consistently in modeling supernova remnants and these dynamics should be noted in the understanding of young supernova remnants.

Enhanced accuracy of x-ray spectra reconstruction from filtered diode array measurements by adding a time integrated spectrometer.

A new approach for the spectral reconstruction of time-dependent emission of soft x-ray sources based on the measurement of filtered x-ray diode array systems is suggested. Two reconstruction methods, based on this approach, are demonstrated using both simulated and measured data. The methods use the filtered x-ray diode measurement together with a co-aligned, time-integrated, spectrally resolved measurement, such as transmission grating spectroscopy. The additional experimental information allows for high accuracy spectral reconstruction, even for plasmas far from local thermodynamic equilibrium where the traditional reconstruction methods may miss some important source spectral features. For the demonstrated cases, the accuracy of the new reconstruction methods is better than 10% for the energy dependent flux and 1% of the total flux, which is higher than the accuracy of previous methods and better than the accuracy of the measurement itself.

Measurements of laser generated soft X-ray emission from irradiated gold foils.

Soft x-ray emission from laser irradiated gold foils was measured at the Omega-60 laser system using the Dante photodiode array. The foils were heated with 2 kJ, 6 ns laser pulses and foil thicknesses were varied between 0.5, 1.0, and 2.0 µm. Initial Dante analysis indicates peak emission temperatures of roughly 100 eV and 80 eV for the 0.5 µm and 1.0 µm thick foils, respectively, with little measurable emission from the 2.0 µm foils.

Observation of Single-Mode, Kelvin-Helmholtz Instability in a Supersonic Flow.

We report the first observation, in a supersonic flow, of the evolution of the Kelvin-Helmholtz instability from a single-mode initial condition. To obtain these data, we used a novel experimental system to produce a steady shock wave of unprecedented duration in a laser-driven experiment. The shocked, flowing material creates a shear layer between two plasmas at high energy density. We measured the resulting interface structure using radiography. Hydrodynamic simulations reproduce the large-scale structures very well and the medium-scale structures fairly well, and imply that we observed the expected reduction in growth rate for supersonic shear flow.

[Determination of molecular glioblastoma subclasses on the basis of analysis of gene expression].

Two glioblastoma groups, which are distinguished from each other by expression level of 416 genes (P < 0.05), were determined using a mathematical model of linear Boolean programming on the basis of gene expression data, obtained by microarray analysis of the glioblastomas and available in Gene Expression Omnibus (GEO) data base. The expression level of 15 genes was more than two-fold higher in the first group of glioblastoma (80 samples) in comparison with the second group (144 samples) and 401 genes and--more than two-fold lower as compared to the second group. 10 of 15 genes, which expression level prevailed in the first group, encode the proteins involved in cell cycle regulation and cell proliferation. A significant percentage of 401 genes are the genes that encode proteins involved in the functioning of neural cells and participating in the processes such as synaptic transmission, neurogenesis, the formation of myelin sheath, axon formation. Kohonen map, built on the basis of the data of 15 genes with prevailed expression in the first group and 60 (of4 01) genes, whose expression level elevated in the second group, confirmed the existence of two glioblastoma groups with specific gene expression profiles. Distribution of the glioblastomas into two groups may reflect two pathways of astrocytic glioma development, one of which leads to the formation of tumors with higher levels of gene expression, which protein products are involved in cell cycle regulation and proliferation. On the other hand, the existence of two molecular variants may reflect different states of glioblastoma progression.

Generalized measurable ignition criterion for inertial confinement fusion.

A multidimensional measurable criterion for central ignition of inertial-confinement-fusion capsules is derived. The criterion accounts for the effects of implosion nonuniformities and depends on three measurable parameters: the neutron-averaged total areal density (rhoR(n)(tot)), the ion temperature (T(n)), and the yield over clean (YOC=ratio of the measured neutron yield to the predicted one-dimensional yield). The YOC measures the implosion uniformity. The criterion can be approximated by chi=(rhoR(n)(tot))(0.8) x (T(n)/4.7)(1.7)YOC(mu)>1 (where rhoR is in g cm(-2), T in keV, and mu approximately 0.4-0.5) and can be used to assess the performance of cryogenic implosions on the NIF and OMEGA. Cryogenic implosions on OMEGA have achieved chi approximately 0.02-0.03.

Rayleigh-Taylor growth measurements in the acceleration phase of spherical implosions on OMEGA.

The Rayleigh-Taylor (RT) growth of 3D broadband nonuniformities was measured using x-ray radiography in spherical plastic shells accelerated by laser light at an intensity of approximately 2 x 10(14) W/cm(2). The 20- and 24-microm-thick spherical shells were imploded with 54 beams on the OMEGA laser system. The shells contained diagnostic openings for backlighter x rays used to image shell modulations. The measured shell trajectories and modulation RT growth were in fair agreement with 2D hydro simulations during the acceleration phase of the implosions with convergence ratios of up to approximately 2.2. Since the ignition designs rely on these simulations, improvements in the numerical codes will be implemented to achieve better agreement with experiments.

Rayleigh-Taylor growth stabilization in direct-drive plastic targets at laser intensities of approximately 1 x 10(15) W/cm2.

Direct-drive, planar-target Rayleigh-Taylor growth experiments were performed for the first time to test fundamental physics in hydrocodes at peak drive intensities of ignition designs. The unstable modulation growth at a drive intensity of approximately 1 x 10(15) W/cm2 was strongly stabilized compared to the growth at an intensity of approximately 5 x 10(14) W/cm2. The experiments demonstrate that standard simulations based on a local model of electron thermal transport break down at peak intensities of ignition designs (although they work well at lower intensities). The preheating effects by nonlocal electron transport and hot electrons were identified as some of the stabilizing mechanisms.

Validation of thermal-transport modeling with direct-drive, planar-foil acceleration experiments on OMEGA.

We present for the first time the experimental validation of the nonlocal thermal-transport model for a National Ignition Facility relevant laser intensity of approximately 10(15) W/cm(2) on OMEGA. The measured thin target trajectories are in good agreement with predictions based on the nonlocal model over the full range of laser intensities from 2 x 10(14) to 10(15) W/cm(2}) The standard local thermal-transport model with a constant flux limiter of 0.06 disagrees with experimental measurements at a high intensity of approximately 10(15) W/cm(2) but agrees at lower intensities. These results show the significance of nonlocal effects for direct-drive ignition designs.

Monoenergetic-proton-radiography measurements of implosion dynamics in direct-drive inertial-confinement fusion.

Time-gated, monoenergetic radiography with 15-MeV protons provides unique measurements of implosion dynamics in direct-drive inertial-confinement fusion. Images obtained during acceleration, coasting, deceleration, and stagnation display a comprehensive picture of spherical implosions. Critical information inferred from such images, hitherto unavailable, characterizes the spatial structure and temporal evolution of self-generated fields and plasma areal density. Results include the first observation of a radial electric field inside the imploding capsule. It is initially directed inward (at approximately 10(9) V/m), eventually reverses direction ( approximately 10(8) V/m), and is the probable consequence of the evolution of the electron pressure gradient.

Studies of plastic-ablator compressibility for direct-drive inertial confinement fusion on OMEGA.

The compression of planar plastic targets was studied with x-ray radiography in the range of laser intensities of I approximately 0.5 to 1.5x10(15) W/cm2 using square (low-compression) and shaped (high-compression) pulses. Two-dimensional simulations with the radiative hydrocode DRACO show good agreement with measurements at laser intensities up to I approximately 10(15) W/cm2. These results provide the first experimental evidence for low-entropy, adiabatic compression of plastic shells in the laser intensity regime relevant to direct-drive inertial confinement fusion. A density reduction near the end of the drive at a high intensity of I approximately 1.5x10(15) W/cm2 has been correlated with the hard x-ray signal caused by hot electrons from two-plasmon-decay instability.

Role of hot-electron preheating in the compression of direct-drive imploding targets with cryogenic D2 ablators.

The compression of direct-drive, spherical implosions is studied using cryogenic D2 targets on the 60-beam, 351-nm OMEGA laser with intensities ranging from approximately 3x10(14) to approximately 1x10(15) W/cm2. The hard-x-ray signal from hot electrons generated by laser-plasma instabilities increases with laser intensity, while the areal density decreases. Mitigating hot-electron production, by reducing the laser intensity to approximately 3x10(14) W/cm2, results in areal density of the order of approximately 140 mg/cm2, in good agreement with 1D simulations. These results will be considered in future direct-drive-ignition designs.

High-areal-density fuel assembly in direct-drive cryogenic implosions.

The first observation of ignition-relevant areal-density deuterium from implosions of capsules with cryogenic fuel layers at ignition-relevant adiabats is reported. The experiments were performed on the 60-beam, 30-kJUV OMEGA Laser System [T. R. Boehly, Opt. Commun. 133, 495 (1997)10.1016/S0030-4018(96)00325-2]. Neutron-averaged areal densities of 202+/-7 mg/cm2 and 182+/-7 mg/cm2 (corresponding to estimated peak fuel densities in excess of 100 g/cm3) were inferred using an 18-kJ direct-drive pulse designed to put the converging fuel on an adiabat of 2.5. These areal densities are in good agreement with the predictions of hydrodynamic simulations indicating that the fuel adiabat can be accurately controlled under ignition-relevant conditions.

High-rhoR implosions for fast-ignition fuel assembly.

Thick, 40 microm plastic shells filled with 25-35 atm of D2 or D3He were imploded on a low-adiabat (alpha approximately 1.3) and with a low-implosion velocity ( approximately 2 x 10(70 cm/s) on the OMEGA laser to generate massive cores of compressed plasma with high areal densities optimal for fast ignition. The targets are driven by 20-kJ relaxation adiabat-shaping laser pulses to keep the inner portion of the shell nearly Fermi degenerate. The measured kinetic energy downshift of proton spectra is in good agreement with the theoretical predictions yielding burn-averaged areal densities of 0.130+/-0.017 g/cm2 and peak rhoR during the burn of about 0.24+/-0.018 g/cm2, the largest rhoR measured on OMEGA to date. The same implosions with empty plastic shells are expected to reach 1.3 g/cm2 across the core (i.e., 2rhoR) enough to stop fast electrons with energies up to 4.5 MeV typical of fast ignition scenarios.

Shock-wave mach-reflection slip-stream instability: a secondary small-scale turbulent mixing phenomenon.

Theoretical and experimental research, on the previously unresolved instability occurring along the slip stream of a shock-wave Mach reflection, is presented. Growth rates of the large-scale Kelvin-Helmholtz shear flow instability are used to model the evolution of the slip-stream instability in ideal gas, thus indicating secondary small-scale growth of the Kelvin-Helmholtz instability as the cause for the slip-stream thickening. The model is validated through experiments measuring the instability growth rates for a range of Mach numbers and reflection wedge angles. Good agreement is found for Reynolds numbers of Re 2 x 10(4). This work demonstrates, for the first time, the use of large-scale models of the Kelvin-Helmholtz instability in modeling secondary turbulent mixing in hydrodynamic flows, a methodology which could be further implemented in many important secondary mixing processes.

Observation of self-similar behavior of the 3D, nonlinear Rayleigh-Taylor instability.

The Rayleigh-Taylor unstable growth of laser-seeded, 3D broadband perturbations was experimentally measured in the laser-accelerated, planar plastic foils. The first experimental observation showing the self-similar behavior of the bubble size and amplitude distributions under ablative conditions is presented. In the nonlinear regime, the modulation sigma(rms) grows as alpha(sigma)gt(2), where g is the foil acceleration, t is the time, and alpha(sigma) is constant. The number of bubbles evolves as N(t) alpha(omegat sq.rt(9) + C)(-4) and the average size evolves as (t) alpha omega(2)gt(2), where C is a constant and omega = 0.83 +/- 0.1 is the measured scaled bubble-merging rate.

High initial amplitude and high Mach number effects on the evolution of the single-mode Richtmyer-Meshkov instability.

Effects of high-Mach numbers and high initial amplitudes on the evolution of the single-mode Richtmyer-Meshkov shock-wave induced hydrodynamic instability are studied using theoretical models, experiments, and numerical simulations. Two regimes in which there is a significant deviation from the linear dependence of the initial velocity on the initial perturbation amplitude are defined and characterized. In one, the observed reduction of the initial velocity is primarily due to large initial amplitudes. This effect is accurately modeled by a vorticity deposition model, quantifying both the effect of the initial perturbation amplitude and the exact shape of the interface. In the other, the reduction is dominated by the proximity of the shock wave to the interface. This effect is modeled by a modified incompressible model where the shock wave is mimicked by a moving bounding wall. These results are supplemented with high initial amplitude Mach 1.2 shock-tube experiments, enabling separation of the two effects. It is shown that in most of the previous experiments, the observed reduction is predominantly due to the effect of high initial amplitudes.

Direct detection of low-concentration NO in physiological solutions by a new GaAs-based sensor.

Nitric oxide (NO) acts as a signal molecule in the nervous system, as a defense against infections, as a regulator of blood pressure, and as a gate keeper of blood flow to different organs. In vivo, it is thought to have a lifetime of a few seconds. Therefore, its direct detection at low concentrations is difficult. We report on a new type of hybrid, organic-semiconductor, electronic sensor that makes detection of nitric oxide in physiological solution possible. The mode of action of the device is described to explain how its electrical resistivity changes as a result of NO binding to a layer of native hemin molecules. These molecules are self-assembled on a GaAs surface to which they are attached through a carboxylate binding group. The new sensor provides a fast and simple method for directly detecting NO at concentrations down to 1 microM in physiological aqueous (pH=7.4) solution at room temperature.