Effects of nanodispersed iron on the morphofunctional parameters of the blood system.

The effects of nanodispersed iron forms on the morphology and function of the blood system were studied. Maghemite and lepidocrocite caused a leukocytic shift towards segmented neutrophil forms, reduction of lymphocyte rigidity, and stimulated their compactization. In addition, the counts of small hyperchromatic erythrocytes with high rigidity increased in the blood flow. The results indicated that a single dose of nanodispersed iron-containing drugs improved the blood respiratory function and its microrheology.

[Use of atomic force microscopy for estimation of the morphometric indices of blood cells].

The possibility of using the atomic-force microscopy for the evaluation of the geometrical characteristics of blood cells has been shown. It has been found by comparing the hemocyte morphometric indices obtained at different modes of scanning that noncontact and semicontact methods are adequate for the estimation of the size and geometry of biological objects. The scanning of cells in the semicontact mode leads to the irreversible deformation of samples.

[Blood lipid levels in various forms of ischemic heart disease]. / Soderzhanie lipidov krovi pri razlichnykh formakh ishemicheskoi bolezni serdtsa.

Enzyme assays of major blood lipid parameters detected no differences between peripheral venous blood specimens of normal subjects and functional cardiologic patients, nor between peripheral and central flow specimens of patients with neurocirculatory dystonia. Alpha cholesterol was typically decreased in all types of coronary disease, the decrease being particularly marked in central cardiac flow. Chronic coronary disease is associated with a rise of total cholesterol, its atherogenic fractions, the atherogenic coefficient and blood triglycerides, as compared to the respective parameters of functional cardiac patients. Acute and subacute coronary disease is associated with decreased blood lipid values, as compared to chronic coronary disease. Blood lipid phenotyping and secondary preventive procedures should rather be done in the absence of aggravations.