Monitoring of optic sheath diameter during acute migraine attack: an objective criteria for the severity of disease.

BACKGROUND: The etiology of migraine can be complex and multifactorial but not clear, also, intracranial pressure has been already associated with migraine attacks. This study aimed to monitor intracranial pressure during migraine attack to understand the possible relations with disease and severity. METHODS: A prospective randomized study was designed. Patients with a definitive diagnosis of migraine underwent ultrasonography for optic nerve sheath diameter (ONSD) measurement before treatment and were re-measured after the attack was resolved. The severity of the migraine was assessed with Headache Impact Test-6 (HIT-6) and Migraine Disability Assessment (MIDAS) questionnaire before the treatment and after the symptoms regressed. ONSD values and scores from the questionnaires were compared before and after the migraine attack. RESULTS: The study included 11 (52.4%) women and 10 (47.6%) men, and 42 eyes were evaluated. ONSD was detected as 4.23 ± 0.26 mm in the right eye and 4.10 ± 0.32 mm in the left eye during the migraine attack and decreased to 3.65 ± 0.41 mm in the right eye and 3.50 ± 0.33 mm in the left eye after the attack was treated (p < 0.001, both). A similar statistical improvement was found in HIT-6 and MIDAS scores with ONSD after treatment (p < 0.001). A significant positive correlation was found between the ONSD value in both eyes and HIT-6/MIDAS scores during the migraine attack, and also, after the migraine attack. CONCLUSION: A subjective increase of ONSD values during the migraine attack decreased after the disease resolved, also changes in ONSD values were significantly correlated with the severity of symptoms.

Diagnostic and predictive value of resistive / pulsatility indices of ophthalmic artery and common carotid artery for the development of diabetic retinopathy.

BACKGROUND: Ophthalmic artery resistive index (OA RI) was a controversial parameter to show hemodynamic changes due to diabetic retinopathy (DRP). PURPOSE: To investigate the diagnostic and predictive value of resistive and pulsatility index (RI and PI, respectively) of OA and common carotid artery (CCA) for the development of DRP. MATERIAL AND METHODS: A total of 60 patients with diabetes mellitus (DM) type 2 (study group) and 30 healthy participants (control group) were evaluated between January and June 2021 by Doppler ultrasonography (DUS). RI and PI values were compared between groups with a Student's t-test. Cutoff value, sensitivity, and specificity were calculated for the significant variables with receiver operating characteristic (ROC) analysis. RESULTS: In total, there were 20 (22.2%) patients with DM without DRP (DMwoRP), 20 (22.2%) patients in the non-proliferative diabetic retinopathy group (NPDRP), and 20 (22.2%) patients in the proliferative diabetic retinopathy group (PDRP). The mean of CCA RI and OA RI in the PDRP group was significantly higher than in the other three groups (P < 0.001). The mean of CCA RI and OA RI was significantly higher in the PDRP group than in the NPDRP group, and in the NPDRP group compared to the DMwoRP group. CCA RI and OA RI showed a significantly high correlation (r = 0.849; P < 0.001). Sensitivity was 95% and specificity was 100% for the diagnosis of PDRP for the 0.82 cutoff value of OA RI (AUR = 0.999, 95% confidence interval for AUC = 0.997-0.1000; P < 0.001). CONCLUSION: The OA RI accurately reflects DRP-induced orbital blood flow changes and is a predictive index for DRP prognosis.

Morbidity and mortality associated with fracture of the sternum due to blunt trauma, by fracture type and location.

Objective: To examine the relationship that the types and locations of fractures of the sternum have with mortality and morbidity. Materials and Methods: We analyzed the records of 115 patients diagnosed with fracture of the sternum, due to blunt trauma, between 2007 and 2018. Records of computed tomography studies were obtained from the radiology archive of a tertiary teaching hospital. The type of fracture was classified as linear, displaced, or comminuted, whereas the fracture location was classified as the manubrium, body, or xiphoid process. Results: A total of 108 patients were included in the study. Of those patients, 92 (85.2%) were male and 16 (14.8%) were female. The etiology was a traffic accident in 72 cases (62.6%) and a fall from height in 36 (31.3%). The mean age was 42.1 ± 17.7 years for males and 53.9 ± 20.0 years for females. The mortality rate was 11.1%. Among the 12 deceased patients, the mean age was 44.4 ± 18.3 years. The fracture was located exclusively in the manubrium in 64 patients (59.3%), exclusively in the body of the sternum in 41 (38.0%), and in both locations in three (2.7%), whereas none were located in the xiphoid process. Morbidity rates were higher in the patients with fractures of the manubrium than in those with fractures of the body of the sternum, as was the incidence of accompanying bone fractures and organ injuries. The fracture was linear in 44 patients (40.7%), displaced in 62 (57.4%), and comminuted in 30 (27.8%). The mortality was significantly higher for comminuted fractures than for the other fracture types (p = 0.045; ß = 4.40). Conclusion: Fracture of the manubrium can be indicative of the severity of trauma and has a poor prognosis.

Objetivo: Examinar a relação entre o tipo e a localização da fratura de esterno com mortalidade e morbidade. Materiais e Métodos: Foram analisados os prontuários de 115 pacientes com diagnóstico de fratura de esterno por trauma contuso entre 2007 e 2018. Os registros de estudos de tomografia computadorizada foram obtidos do arquivo de radiologia de um hospital universitário terciário. O tipo de fratura foi classificado como linear, deslocado ou cominutivo, enquanto o local da fratura foi classificado como no manúbrio, no corpo ou no processo xifoide. Resultados: Cento e oito pacientes foram incluídos no estudo. Desses, 92 (85,2%) eram do sexo masculino e 16 (14,8%) eram do sexo feminino. As causas foram acidente de trânsito em 72 casos (62,6%) e queda de altura em 36 (31,3%). A média de idade foi de 42,1 ± 17,7 anos para os homens e de 53,9 ± 20,0 anos para as mulheres. A taxa de mortalidade foi de 11,1%. Entre os 12 pacientes que faleceram, a média de idade foi de 44,4 ± 18,3 anos. A fratura localizou-se apenas no manúbrio em 64 pacientes (59,3%), somente no corpo do esterno em 41 (38,0%) e em ambas as localizações em três pacientes (2,7%), e nenhuma ocorreu no apêndice xifoide. As taxas de morbidade foram maiores nos pacientes com fraturas no manúbrio do que nos com fraturas no corpo do esterno, assim como a incidência de fraturas ósseas e lesões de órgãos adjacentes. A fratura foi linear em 44 pacientes (40,7%), deslocada em 62 (57,4%) e cominutiva em 30 (27,8%). A mortalidade foi significativamente maior nos casos de fraturas cominutivas do que em outros tipos de fratura (p = 0,045; ß = 4,40). Conclusão: A fratura do manúbrio pode ser um indicativo da gravidade do trauma e de mau prognóstico.

Unusual imaging characteristics of thoracic hydatid disease.

Cystic echinococcosis (hydatid disease) is a zoonotic parasitic disease, caused by ingestion of Echinococcus granulosus eggs, that can result in cyst formation anywhere on the body. Hydatid disease is frequently seen in regions where there is human-animal contact and poor socioeconomic development. The prevalence of the disease ranges from 0 to 79 cases/100,000 population. Hydatid cysts are typically found in the liver and lungs, being less common in other parts of the body. Computed tomography or magnetic resonance imaging is often used in order to clarify the sites affected by a hydatid cyst, such as the cranial and thoracic regions, which also facilitates the surgical evaluation and minimizes complications. Although rare, hydatid cysts in atypical locations can provoke unusual complications, with unpredictable findings and symptoms. This essay discusses the radiological aspects of rare thoracic hydatid cysts.

A equinococose cística (doença hidática) é uma doença parasitária zoonótica causada pela ingestão de ovos de Echinococcus granulosus, que pode resultar na formação de cistos em qualquer parte do corpo. A doença hidática é frequentemente vista em regiões onde há contato humano-animal e baixo desenvolvimento socioeconômico. A prevalência da doença varia de 0 a 79 casos/100.000 habitantes. Os cistos hidáticos são normalmente encontrados no fígado e nos pulmões, sendo menos comuns em outras partes do corpo. A tomografia computadorizada ou a ressonância magnética são frequentemente utilizadas para indicar os locais afetados por um cisto hidático, como as regiões craniana e torácica, o que também facilita a avaliação cirúrgica e minimiza complicações. Embora raros, os cistos hidáticos em locais atípicos podem provocar complicações incomuns, com achados e sintomas imprevisíveis. Este ensaio discute os aspectos radiológicos dos raros cistos hidáticos no tórax.

Platelet-Rich Plasma Treatment for Accelerated Androgenetic Alopecia Pattern Hair Loss After COVID-19 Infection: A Case Series.

BACKGROUND: Hair-related manifestations such as alopecia areata or telogen effluvium were reported during COVID-19 disease. Accelerated hair loss with androgenetic alopecia (AGA) pattern or management has not been discussed before. AIMS: This study aimed to examine the accelerated AGA pattern hair loss and management with PRP treatment. MATERIALS AND METHODS: This study was designed prospectively and nine patients included to study confirmed PCR test for COVID-19 infection. Patients underwent platelet-rich plasma (PRP) injections for 4 sessions. Results were accessed with the hair pull test (HPT) and self-administered hair growth questionnaire (HGQ). RESULTS: Nine patients were admitted with complaints of hair loss after an average of 220 ± 24.2 (min: 182 max: 264) day after recovery of COVID-19. Mean age of the patients was 33.8 ±8.4 years old (min: 26, max: 52). Six (66.7%) patients were male, and three (33.3%) of them were female. HPT score decreased to 6.0 ± 1.6 after the first PRP application (p = 0.007, CI 95%:2.7-5.2) and decreased to 1.2 ± 0.8 after the last PRP session (p = 0.008, CI 95%: 6.4-11.1). Five (55.5%) of the patients described the treatment as "very effective" after treatment with HGQ. CONCLUSIONS: Accelerated hair loss associated with COVID-19 continues in long term and PRP treatment provides a satisfactory solution.

Correlation of the Neutrophil-to-Lymphocyte Ratio with the Middle Ear Risk Index in Patients with Chronic Otitis Media.

This study aimed to investigate the neutrophil-to-lymphocyte ratio (NLR) and severity of the chronic otitis media according to middle ear risk index (MERI) scores. The NLR and middle ear risk index were calculated for 210 chronic otitis media (COM) patients retrospectively. NLR compared between COM patients and 159 participants in control group. Pearson correlation analysis was performed for NLR and MERI. In addition, The cut-off value, sensitivity, and specificity for NLR were determined in COM according to the severity of the disease with ROC analysis. The average of NLR in all patients was 1.94 ± 0.89. NLR was calculated as 2.05 ± 1.03 in the patients with COM and 1.79 ± 0.64 in the control group (p = 0.006, 95% CI 0.07-0.44, t test). According to the ROC analysis, the cut-off point was determined as 1.95 for moderate and severe disease in MERI. For the cut of a NLR = 1.95, sensitivity was calculated as 48.5% and the specificity 57.1% for moderate and severe COM. MERI score was found significantly higher in patients with postoperative graft perforation (p < 0.001, 95% CI 0.7-1.8). NLR has not related significantly with the MERI score according to linear regression analysis (p = 0.927). NLR was found to be significantly higher in chronic otitis media patients compared to the control group. But NLR was not related to the severity of the disease classified with MERI. The cut-off value, sensitivity and sensitivity rates of NLR obtained was not available for clinically use.

Intramuscular hydatid cyst in the lower extremity: report of three cases.

Hydatid cysts are rarely detected in the muscle tissue, even in endemic countries. Echinococcus granulosis is the most common causative agent, whereas Echinococcus alveolaris is rare. Three patients, two females and one male, with primary echinococcosis of the skeletal muscles are described in this report. Mean patient age was 33.3 ± 14.6 years. The disease occurred as soft tissue masses in all three patients, and no hydatid foci were detected elsewhere in the patients. Skeletal muscle echinococcosis should be considered in the differential diagnosis of limb masses, especially in endemic countries.