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Introduction: Using three-dimensional printed duplicates of the donor teeth, three-dimensional auto-transplantation is a medical procedure that moves a tooth from one location inside a patient to another. The intraoperative practicability during 3D auto-transplantation of teeth was evaluated in the present study. Material and Methods: A prospective multicenter clinical study was done among the subjects. "Preoperative cone-beam computed tomography imaging," "computer-assisted design (CAD)," and "computer-assisted manufacturing (CAM)" were used in all operations to make a 3D duplicate of the donor teeth. The clinical parameters that were evaluated were the time required for the fit, number of attempts to fit, and intra-operative experience. Results: Canines, premolars, molars, and one extra tooth were all transplanted during the 200 auto-transplantation surgeries among 152 subjects. An initial satisfactory fit of the donor tooth and an extra-alveolar time of less than one minute were achieved in 80% of the surgeries. The extra-alveolar time exceeded 3 minutes in ten teeth. Difficulties that were faced were related to the imaging, patient cooperation, and the bone quality. Conclusions: The application of the duplicate teeth by 3D printing of a donor tooth all through auto-transplantation techniques reduced the time the tooth stays extra-alveolar as well as the efforts at transplant fitting during implantation. This allowed for more challenging surgeries as well as a speedy and reliable therapy.
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BACKGROUND: Internet-based education is having few advantages since it increases an emphasis on the education system based on problems by incorporation of both visual as well as interactive tools. Also, some contributions to practical skills can be made using pictorial as well as video-based knowledge. The present study aimed to assess the knowledge, attitude, and perception of dental undergraduates towards mobile and digital learning methods in India. MATERIALS AND METHODS: This was a cross-sectional questionnaire-based study conducted after obtaining Institutional Ethical Review Board permission. Before commencing the study, the purpose of the study was explained to the study participants and written informed consent was obtained. About 200 undergraduate students of dentistry in a single institution were selected as a convenient sample. Information obtained from responses was entered into an Excel sheet (Microsoft Corporation) and was further analyzed. Data collection was done for a period of one month. Statistical analysis: Obtained data were recorded and subjected to statistical analysis by use of statistical SPSS software (version 20.0, IBM). Descriptive statistical data were recorded as frequencies or percentages. Chi-square statistical test was used for the assessment of responses obtained from dental undergraduate students. The level of significance was fixed at a probability of <0.05. RESULTS AND OBSERVATIONS: On statistically analyzing, 99% of students were found to possess knowledge regarding the use of mobile phones for digital education. A good statistical correlation was obtained between attitude and perception regarding accessing digital learning using mobile phones. CONCLUSION: In the present study, good knowledge, attitude, and perception regarding the use of digital learning using phones were found among Indian dental undergraduates.
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The study illustrates an application of evidence data for performing Total Interpretive Structural Modeling (TISM). TISM is widely used to analyze the critical success factors or inhibitors and their interlinkages. This study uses learning from evidence data, specifically social media analytics, to identify the relationship between the elements. Thus, it leads to the advancement of the TISM-P methodology with evidence-based TISM (TISM-E). This study uses Twitter as a source of evidence data. Further, 2,60,297 tweets were used to illustrate the process of TISM-E. The paper demonstrates the application of TISM-E for the success of the COVID-19 vaccination drive. The pandemic effects are long-term; therefore, the hierarchical model developed shows a sustainable approach for vaccinating maximum population. Further, the framework developed will ensure the distribution efficacy of vaccines. In addition, it will aid practitioners in developing future vaccination policies. The enhanced model provides evidence for polarity (positive/negative) of relationships and can help to build propositions for theory development. The study contributes to healthcare, modeling research, and graph-theoretic literature.
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Bacopa monnieri is the main source of pharmaceutically important bacosides; however, the low content of these molecules in planta remains a limiting factor for fulfilling the industrial requirement. The accumulation of secondary metabolites can be enhanced in plants upon inoculation with endophytes. In this study, we isolated and analyzed the culturable endophytes associated with different plant parts. By analyzing their impact on plant growth parameters (in vitro and in vivo) and Bacoside A content, we found few candidates which increased bacoside accumulation significantly. Finally, two promising endophytes namely Bacillus subtilis (OK070745) and Klebsiella aerogenes (OK070774) were co-cultivated with B. monnieri cuttings singly and in combination mode to clarify their effect on bacoside biosynthesis and their accumulation in B. monnieri shoot. Consortium-inoculated plants significantly enhanced the plant biomass and Bacoside A content with respect to single inoculation. The results of real-time quantitative (RT-PCR) revealed significant accumulation of bacoside biosynthetic pathway transcripts (HMGCR, PMVK, FDPS, SQS, and ß-AS) in the case of plants inoculated with microbial combination, while the single inoculation of B. subtilis diverted the plant's machinery toward the synthesis of phenylpropanoid genes like CCR, CAD, CHS, and HST. In addition, higher expression of MYB 2 and WRKY 1 transcription factors in combinational treatment points out their probable role in better physiological and developmental processes. Altogether, this is the first study on B. monnieri-endophyte interaction showing improvement in the accumulation of bacoside A by modulating various genes of metabolic pathway and thus suggests an effective "green approach" for augmenting in planta production of pharmaceutically important bacosides.
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In the year 2020, the Global Journal of Flexible Systems Management (GJFSM) has celebrated its two decades of publication. This study is an attempt to commemorate the two decades of publication by presenting the overview of the GJFSM along with the trajectory of flexibility research in various journals. By using multiple bibliometric tools and indicators, the study finds that the GJFSM has grown over the years in terms of total publications and citations. The contributors are from across the globe, i.e., South America, North America, Asia, Europe, Africa, and the Pacific. The Journal publishes several flexibility areas, including information systems flexibility, financial flexibility, supply chain flexibility, technology management flexibility, marketing flexibility, organizational flexibility, strategic flexibility, and manufacturing flexibility. The GJFSM is cited by authors from various countries across the globe. It has been cited across different Scopus categorizations, including "Strategy and Management," "Business and International Management," "General Business, Management and Accounting," "Industrial and Manufacturing Engineering," and "Management Science and Operations Research." Keyword co-occurrences analysis helps to analyze the various groups of keywords cited together in the GJFSM. Co-citation analysis of references helps to identify crucial clusters of GJFSM, i.e., strategic flexibility, manufacturing flexibility, the conceptual framework of flexibility, supply chain flexibility, modeling flexibility, and application of TISM. Overall, GJFSM has seen an increase in both publications and citations, reflecting its increasing presence among the journals publishing flexibility research. The diversity of flexibility research and its contributions to research under-one-roof make this Journal unique. The paper concludes with the gap areas of flexibility research and the way forward.
