RESUMEN
PURPOSE: Invasive breast carcinomas and fibroadenomas are often difficult to differentiate in dynamic contrast-enhanced T1-weighted MR imaging of the breast, because both tumors can enhance strongly after contrast injection. The purpose of this study was to evaluate whether the addition of T2*-weighted first pass perfusion imaging can increase the differentiation of malignant from benign lesions. MATERIAL AND METHODS: Nine patients with invasive carcinomas and 10 patients with contrast enhancing fibroadenomas were examined by a dynamic contrast-enhanced T1-weighted 3D sequence immediately followed by a single slice T2*-weighted first pass perfusion sequence positioned in the contrast-enhancing lesion. RESULTS: The carcinomas and the fibroadenomas were impossible to differentiate based on the contrast enhancement characteristics in the T1-weighted sequence. The signal loss in the T2*-weighted perfusion sequence was significantly stronger in the carcinomas than in the fibroadenomas (p = 0.0004). CONCLUSION: Addition of a T2*-weighted first pass perfusion sequence with a high temporal resolution can probably increase the differentiation of fibroadenomas from invasive carcinomas in contrast-enhanced MR imaging of the breast.
Asunto(s)
Neoplasias de la Mama/diagnóstico , Carcinoma Ductal de Mama/diagnóstico , Medios de Contraste , Fibroadenoma/diagnóstico , Enfermedad Fibroquística de la Mama/diagnóstico , Gadolinio DTPA , Procesamiento de Imagen Asistido por Computador , Imagen por Resonancia Magnética , Lesiones Precancerosas/diagnóstico , Adulto , Anciano , Mama/patología , Diagnóstico Diferencial , Femenino , Humanos , Aumento de la Imagen , Inyecciones Intravenosas , Persona de Mediana Edad , Sensibilidad y EspecificidadRESUMEN
At least 20,000 Norwegian women have silicone breast implants, either for breast augmentation or for reconstruction. One of the complications associated with breast implants is rupture of the implants. Magnetic resonance imaging (MRI) has been shown to be the most accurate imaging modality for evaluating the integrity of breast implants. Recognition of the different types of implants and the appearance of normal implants on MRI is very important for distinguishing these from intracapsular and extracapsular ruptures. Examples are shown of MRI findings in normal and ruptured implants.
