RESUMEN
BACKGROUND: Information about vaccine-preventable diseases (VPDs) and vaccinations should be included throughout nursing curricula to prepare future nurses to promote vaccination with patients and combat misinformation. METHOD: In a large, pre-nursing course, faculty designed a self-directed activity focused on VPDs and vaccinations that required students to analyze various sources and create presentations about these topics. RESULTS: Student feedback indicated the learning outcomes of this educational intervention were largely met and that students felt positive about this type of activity overall. CONCLUSION: Including information in early nursing courses regarding VPDs and vaccinations can positively influence students' knowledge, confidence, and perceptions of these topics. Independent student projects involving higher cognitive domain levels can be successfully integrated into large pre-nursing courses. [J Nurs Educ. 2024;63(X):XXX-XXX.].