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2.
Gig Tr Prof Zabol ; (5): 36-8, 1992.
Artículo en Ruso | MEDLINE | ID: mdl-1427353

RESUMEN

Reports of MACs for carboxylic acid derivatives as sodium methoxyacetate (SMOA), methyl chlorpropionate (MCP) and acetoacetic ether (AAE). SMOA shows low toxicity, no cumulation and specific action MCP demonstrates moderate toxicity, low cumulation no specific action in concentrations close to Limac. AAE presents toxicity low in oral usage and moderate when inhaled, low cumulation, no irritation and sensitization. Tentative safe level of injury and MAC estimated for the aforesaid substances together with toxicity parameters compared with the substances studied before allowed the authors to set the MAC of SMOA--10, MCP--2, AAE--10 mg/m3.


Asunto(s)
Contaminantes Ocupacionales del Aire/toxicidad , Ácidos Carboxílicos/toxicidad , Modelos Biológicos , Acetatos/toxicidad , Acetoacetatos/toxicidad , Animales , Relación Dosis-Respuesta a Droga , Cobayas , Hidrocarburos Clorados , Dosificación Letal Mediana , Matemática , Concentración Máxima Admisible , Ratones , Propionatos/toxicidad , Ratas
7.
Gig Sanit ; (9): 24-6, 1989 Sep.
Artículo en Ruso | MEDLINE | ID: mdl-2591778

RESUMEN

Proceeding from the experimental study of neopinamine insecticide toxicity its hygienic standardization was carried out. Since neopinamine had moderate toxicity under its acute and chronic effect and different routes of body intake, its accumulation was absent and its impact was selective in the occurrence of aftereffects, this preparation was attributed to the third class of danger. Neopinamine MAC in the workplace air was recommended at the level of 5 mg/m3.


Asunto(s)
Contaminantes Atmosféricos/toxicidad , Piretrinas/toxicidad , Toxicología/normas , Animales , Relación Dosis-Respuesta a Droga , Evaluación Preclínica de Medicamentos , Cobayas , Insecticidas , Concentración Máxima Admisible , Ratones , Piretrinas/administración & dosificación , Piretrinas/normas , Conejos , Ratas
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