RESUMEN
The effectiveness and safety of treatment with vobenzyme supplemented to the standard antibiotic therapy have been compared in 60 patients. Addition of vobenzyme to the standard antibiotic therapy significantly reduces the number and degree of respiratory symptoms has a pronounced effect on the activity of inflammation, leads to a more complete reversal of pulmonary parenchymatous infiltration on a roentgenogram, contributes to the achievement of the maximum efficiency of treatment, and substantially diminishes residual respiratory symptoms of pneumonia economically expediently and safety at a late follow-up.
Asunto(s)
Infecciones Comunitarias Adquiridas/tratamiento farmacológico , Terapia Enzimática , Neumonía Bacteriana/tratamiento farmacológico , Adolescente , Adulto , Anciano , Antibacterianos/uso terapéutico , Infecciones Comunitarias Adquiridas/diagnóstico por imagen , Relación Dosis-Respuesta a Droga , Quimioterapia Combinada , Enzimas/administración & dosificación , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Neumonía Bacteriana/diagnóstico por imagen , Radiografía Torácica , Resultado del Tratamiento , Adulto JovenAsunto(s)
Ampicilina/administración & dosificación , Muramidasa/administración & dosificación , Neumonía/tratamiento farmacológico , Enfermedad Aguda , Adulto , Ampicilina/farmacocinética , Disponibilidad Biológica , Sinergismo Farmacológico , Quimioterapia Combinada , Humanos , Inyecciones Intramusculares , Persona de Mediana Edad , Neumonía/metabolismo , Neumonía Neumocócica/tratamiento farmacológico , Neumonía Neumocócica/metabolismoRESUMEN
The influence of the preparation of mucolytic enzymes obtained from the culture liquid filtrate of Actinomyces griseinus on the yeast Candida guilliermondii was investigated. Lipids, hydrocarbons and proteins were extracted and free amino acids were separated from the biomass made of disrupted yeast cells. The extract contained 73% of cytoplasmic substances whereas normal yeast (enzymically untreated) contain on the average 13.7%. Lipids and hydrocarbons were measured.
