RESUMEN
Silk is an attractive biomaterial for use in tissue engineering applications because of its slow degradation, excellent mechanical properties, and biocompatibility. In this report, we demonstrate a simple method to cast patterned films directly from silk fibroin dissolved in an ionic liquid. The films cast from the silk ionic liquid solution were found to support normal cell proliferation and differentiation. The versatility of the silk ionic liquid solutions and the ability to process large amounts of silk into materials with controlled surface topography directly from the dissolved silk ionic liquid solution could enhance the desirability of biomaterials such as silk for a variety of applications.
Asunto(s)
Proliferación Celular , Fibroínas , Seda , Ingeniería de Tejidos/métodos , Animales , Materiales Biocompatibles , Diferenciación Celular , Línea Celular , Humanos , Iones , Técnicas de Cultivo de TejidosRESUMEN
The formation of silica- and titania-coated single-wall carbon nanotubes (SWNTs) using a mutlifunctional peptide to both suspend SWNTs and direct the precipitation of silica and titania at room temperature is demonstrated.
Asunto(s)
Aminoácidos Aromáticos/química , Nanotubos de Carbono/química , Péptidos/química , Secuencia de Aminoácidos , Microscopía de Fuerza Atómica , Datos de Secuencia Molecular , Nanotubos de Carbono/ultraestructura , Biblioteca de Péptidos , Dióxido de Silicio/química , Titanio/químicaRESUMEN
The diameter of single walled carbon nanotubes (SWNTs) determines the electronic properties of the nanotube. The diameter of carbon nanotubes is dictated by the diameter of the catalyst particle. Here we describe the use of iron nanoparticles synthesized within the Dps protein cage as catalysts for the growth of single-walled carbon nanotubes. The discrete iron particles synthesized within the Dps protein cages when used as catalyst particles gives rise to single-walled carbon nanotubes with a limited diameter distribution.
RESUMEN
Dip-pen nanolithography (DPN) is becoming a popular nano-patterning technique for depositing materials onto a substrate using the probe of an atomic force microscope (AFM). Here, we demonstrate the deposition of a short synthetic peptide by DPN using the Tapping Mode of AFM rather than the commonly used contact mode. DPN in Tapping Mode requires drive amplitude modifications for deposition, yet allows for gentle imaging of the deposited material and enables deposition on soft surfaces.
