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1.
J Pharm Bioallied Sci ; 15(Suppl 1): S326-S329, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37654300

RESUMEN

Anthropometry, fingerprints, age estimation, gender determination, blood types, DNA, and dental features are examples of traditional techniques for identifying a person. The present study aimed toward observing the patterns of fingerprints and their reliability toward human identification. A retrospective study was conducted in a tertiary care unit in Bhubaneswar city. Fingerprints were recorded, and the individual identification mark was noted for each individual. Reporting of the patterns was done. Sir Henry Galton's classification was used to study the fingerprint patterns. IBM Statistical Package for Social Sciences was used for the statistical analysis. Type A was the most common type seen for the right-hand little finger. Type A was the most common type seen for the left-hand little finger; Type C was the most common type seen for the left-hand ring finger. Statistically significant correlations between gender and dermatoglyphics were found, supporting their usage as trustworthy forensic evidence.

2.
Nano Lett ; 23(11): 4916-4922, 2023 Jun 14.
Artículo en Inglés | MEDLINE | ID: mdl-37257060

RESUMEN

Understanding and characterizing the mechanical behavior of colloidal nanocrystal (NC) assemblies are important for developing nanocrystalline materials with exceptional mechanical properties for robust electronic, thermoelectric, photovoltaic, and optoelectronic devices. However, the limited ranges of Young's modulus, hardness, and fracture toughness (≲1-10 GPa, ≲50-500 MPa, and ≲10-50 kPa m1/2, respectively) in as-synthesized NC assemblies present challenges for their mechanical stability and therefore their practical applications. In this work, we demonstrate using a combination of nanoindentation measurements and coarse-grained modeling that the mechanical response of assemblies of as-synthesized NCs is governed by the van der Waals interactions of the organic surface ligands. More importantly, we report tremendous ∼60× enhancements in Young's modulus and hardness and an ∼80× enhancement in fracture toughness of CdSe NC assemblies through a simple inorganic Sn2S64- ligand exchange process. Moreover, our observation of softening in nanocrystalline materials with decreasing CdSe NC diameter is consistent with atomistic simulations.

3.
J Pharm Bioallied Sci ; 12(Suppl 1): S57-S59, 2020 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-33149431

RESUMEN

Chlorhexidine is a cationic bisbiguanide with broad antibacterial activity, and wide spectrum of activity encompassing gram-positive and gram-negative bacteria, yeasts, dermatophytes and some lipophilic viruses. Its antibacterial action is due to the disruption of the bacterial cell membrane by the chlorhexidine molecules, increasing the permeability and resulting in cell lysis. Thus, chlorhexidine plays a key role in the dentistry and is used to treat or prevent periodontal disease, and has earned its eponym of the gold standard. This article reviews in detail about the mechanism of action, indications, forms and various studies related to chlorhexidine.

4.
J Pharm Bioallied Sci ; 12(Suppl 1): S382-S388, 2020 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-33149491

RESUMEN

AIM: The aim of this study was to compare the immunohistochemical expression of survivin in oral potentially malignant disorders (OPMDs) and evaluate its prognostic significance among oral leukoplakia (OL), oral submucous fibrosis (OSMF), and oral lichen planus (OLP). MATERIALS AND METHODS: The study material consisted of 60 formalin-fixed paraffin-embedded tissue samples: 15 cases each of OL, OSMF, OLP, and normal oral mucosal epithelium as control. Survivin expression was analyzed immunohistochemically, and data analysis was accomplished using Statistical Package for Social Sciences, version 22.0 (SPSS Inc., Chicago, IL). Fisher's chi-square test was opted to compare the study groups. RESULTS: Survivin was expressed in all the OPMDs including OL, OSMF, and OLP, but was absent in normal oral tissue samples. Higher immunoreactivity and survivin staining was observed in OLP compared to OL and OSMF whereas OL showed a significant difference in the distribution of survivin immunoexpression against OLP. An increased nuclear expression of survivin along with distribution in the basal and parabasal layers was evident in all OPMDs. CONCLUSION: Survivin was expressed more in OLP in comparison to OSMF and OLP, indicating unfavorable prognosis. OL showed increased expression in comparison to OSMF, showing unfavorable prognosis. On the basis of this study, it was concluded that survivin may be used as an important diagnostic and prognostic marker for OPMDs.

5.
J Pharm Bioallied Sci ; 9(Suppl 1): S4-S10, 2017 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-29284926

RESUMEN

Oral cancer is one of the most commonly occurring malignant tumors in the head and neck regions with high incident rate and mortality rate in the developed countries than in the developing countries. Generally, the survival rate of cancer patients may increase when diagnosed at early stage, followed by prompt treatment and therapy. Recently, cancer diagnosis and therapy design for a specific cancer patient have been performed with the advanced computer-aided techniques. The responses of the cancer therapy could be continuously monitored to ensure the effectiveness of the treatment process that hardly requires diagnostic result as quick as possible to improve the quality and patient care. This paper gives an overview of oral cancer occurrence, different types, and various diagnostic techniques. In addition, a brief introduction is given to various stages of immunoanalysis including tissue image preparation, whole slide imaging, and microscopic image analysis.

6.
Case Rep Dent ; 2014: 869783, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-25548687

RESUMEN

Cherubism is a rare familial multilocular cystic lesion of the jaws. The condition clinically appears as a bilateral symmetric swelling of the cheeks in children and is the primary reason for referral. It is a rare lesion of the jaws that has a dominant pattern of inheritance. We report two cases of cherubism, that of a boy and his mother suggestive of a strong familial incidence. A variety of lesions of the jaw mimic this condition and hence the differential diagnosis has been emphasised.

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