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J Comp Pathol ; 210: 8-14, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38458015

RESUMEN

An 11-year-old male Miniature Dachshund dog was presented with dyschezia. Computed tomography examination 35 days after the initial visit revealed a prostate mass (4.0 × 3.5 × 2.7 cm) and prostatectomy and orchiectomy were performed 13 days later. Grossly, the prostate was rubbery and the cut surface of the mass was swollen. The mass was whitish and demarcated from the surrounding tissues. Microscopically, the mass had a capsulate consisting of atypical spindloid stromal cells arranged in a phyllode pattern and also in a fasciculated pattern admixed with acinar ductal cells. Atypical stromal cells contained round-to-oval finely hyperchromatic nuclei that had distinct nuclei and abundant eosinophilic cytoplasm. Immunohistochemically, the atypical stromal cells were positive for vimentin, CD34, desmin, α-smooth muscle actin, progesterone receptor and androgen receptor but negative for cytokeratin AE1/AE3, p63, c-Kit, DOG-1 and SOX10. On the basis of these findings, the tumour was diagnosed as a prostatic stromal tumour of uncertain malignant potential.


Asunto(s)
Enfermedades de los Perros , Neoplasias de los Tejidos Blandos , Masculino , Animales , Perros , Próstata/patología , Neoplasias de los Tejidos Blandos/patología , Neoplasias de los Tejidos Blandos/veterinaria , Proteínas Proto-Oncogénicas c-kit , Enfermedades de los Perros/patología
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