[Acute experimental pancreatitis in the opossum. The role of prior truncular vagotomy on the inflammatory response]. / Pancreatitis aguda experimental en el opossum. Rol de la vagotomía troncular previa en la respuesta inflamatoria.

BACKGROUND: Acute pancreatitis (AP) is a common cause of admission to the emergency room. Its etiopathogeny is poorly understood. The pancreatic inflammatory response in this process is unclear. The influence of the autonomic nervous system is a controversial issue. AIMS: To demonstrate the effects of truncular vagotomy on AP due to duodenal distention in the South American opossum. PLACE OF APPLICATION: Department of experimental surgery (Churruca-Visca Hospital) INEUCI (Neuroscience Institute, CONICET, UBA). POPULATION: Male and female South American opossum divided into: a control group (7 animals); group A: truncular vagotomy and pyloroplasty seven days after the onset of AP (7 animals). Group B: truncular vagotomy and pyloroplasty 30 days after provoking AP (7 animals). Group C: truncular vagotomy and pyloroplasty 45 days after the onset of AP (7 animals). METHODS: Acute pancreatitis was caused by duodenal distention of the second portion by inserting a Foley catheter through a gastrostomy. CONCLUSIONS: The method of provoking AP is original. The influence of autonomous nervous system is being underestimated in most of the literature available.

Pancreatitis aguda experimental en el opossum. Rol de la vagotomía troncular previa en la respuesta inflamatoria. / [Acute experimental pancreatitis in the opossum. The role of prior truncular vagotomy on the inflammatory response]

BACKGROUND: Acute pancreatitis (AP) is a common cause of admission to the emergency room. Its etiopathogeny is poorly understood. The pancreatic inflammatory response in this process is unclear. The influence of the autonomic nervous system is a controversial issue. AIMS: To demonstrate the effects of truncular vagotomy on AP due to duodenal distention in the South American opossum. PLACE OF APPLICATION: Department of experimental surgery (Churruca-Visca Hospital) INEUCI (Neuroscience Institute, CONICET, UBA). POPULATION: Male and female South American opossum divided into: a control group (7 animals); group A: truncular vagotomy and pyloroplasty seven days after the onset of AP (7 animals). Group B: truncular vagotomy and pyloroplasty 30 days after provoking AP (7 animals). Group C: truncular vagotomy and pyloroplasty 45 days after the onset of AP (7 animals). METHODS: Acute pancreatitis was caused by duodenal distention of the second portion by inserting a Foley catheter through a gastrostomy. CONCLUSIONS: The method of provoking AP is original. The influence of autonomous nervous system is being underestimated in most of the literature available.

[Acute pancreatitis of uncommon etiology: a physiopathologic approach]. / Pancreatitis agudas de etiologías poco frecuentes: una aproximación fisiopatogénica.

A review of 73 cases of acute pancreatitis (A.P.) of *A in frequent etiology is critically analyzed. The patients were allocated to the following categories: post ingestion of a large meal, dyslipemic, post ERCP, post operative, pregnancy, and puerperium linked., post urlian parotiditis, post stress, idiopathic, drug associated, post traumatic. In each of the above groups those hypotheses that are currently primarily accepted as been mainly concerned with the etiopathogenesis of the inflammatory episode were given preference. One factor upon which the authors has put special emphasis is that of frequent involvement of the nervous system through different types of autonomic are reflexes. This pathogenic mechanism is surprisingly disregarded in the literature. The interrelation ship between the severity of an AP episode and the background provided by the "pancreon" secretory activity is also emphasized. The mortality rate of the whole series was of 7 cases (9.6%). The groups that disclosed the highest rates were related to abdominal surgery (50%) and to dyslipemia (17%).

Pancreatitis agudas de etiologías poco frecuentes: una aproximación fisiopatogénica / Acute pancreatitis of uncommon etiology: a physiopathologic approach

Los autores presentan 73 casos de pancreatitis agudas (P.A.) de causas poco frecuentes. Ellas fueron divididas en ingestión copiosa, displémicas, postcolangioretrógrada endoscópica, postoperatorias, tercer trimestre de embarazo, puerperio inmediato, parotídica, por stress e idiopáticas, medicamentosa y por trauma. Se evalúan las teorías etiopatogénicas probables haciendo hincapié en la importancia del Sistema Nervioso Autónomo (S.N.A.) como responsables de las lesiones glandulares. El estado funcional del páncreas, previo al ataque agudo, es uno de los factores predisponentes de mayor envergadura. La mortalidad de la serie fue de 7 casos (9.58 por ciento) siendo las postoperatorias (50 por ciento) y las dislipémicas (16.6 por ciento) las de mayor índice de mortalidad. (AU)

Pancreatitis agudas de etiologías poco frecuentes: una aproximación fisiopatogénica / Acute pancreatitis of uncommon etiology: a physiopathologic approach

Los autores presentan 73 casos de pancreatitis agudas (P.A.) de causas poco frecuentes. Ellas fueron divididas en ingestión copiosa, displémicas, postcolangioretrógrada endoscópica, postoperatorias, tercer trimestre de embarazo, puerperio inmediato, parotídica, por stress e idiopáticas, medicamentosa y por trauma. Se evalúan las teorías etiopatogénicas probables haciendo hincapié en la importancia del Sistema Nervioso Autónomo (S.N.A.) como responsables de las lesiones glandulares. El estado funcional del páncreas, previo al ataque agudo, es uno de los factores predisponentes de mayor envergadura. La mortalidad de la serie fue de 7 casos (9.58 por ciento) siendo las postoperatorias (50 por ciento) y las dislipémicas (16.6 por ciento) las de mayor índice de mortalidad.

Pancreatitis agudas de etiologías poco frecuentes: una aproximación fisiopatogénica. / [Acute pancreatitis of uncommon etiology: a physiopathologic approach]

A review of 73 cases of acute pancreatitis (A.P.) of *A in frequent etiology is critically analyzed. The patients were allocated to the following categories: post ingestion of a large meal, dyslipemic, post ERCP, post operative, pregnancy, and puerperium linked., post urlian parotiditis, post stress, idiopathic, drug associated, post traumatic. In each of the above groups those hypotheses that are currently primarily accepted as been mainly concerned with the etiopathogenesis of the inflammatory episode were given preference. One factor upon which the authors has put special emphasis is that of frequent involvement of the nervous system through different types of autonomic are reflexes. This pathogenic mechanism is surprisingly disregarded in the literature. The interrelation ship between the severity of an AP episode and the background provided by the [quot ]pancreon[quot ] secretory activity is also emphasized. The mortality rate of the whole series was of 7 cases (9.6

). The groups that disclosed the highest rates were related to abdominal surgery (50

) and to dyslipemia (17

).