Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 6 de 6
Filtrar
Más filtros










Base de datos
Intervalo de año de publicación
1.
Acta Neuropathol Commun ; 7(1): 122, 2019 Jul 29.
Artículo en Inglés | MEDLINE | ID: mdl-31358068

RESUMEN

In the original publication of this article [1] the term 'National Rugby League (NRL)' was used to refer to professional rugby league competition sport in Australia. The term should have read 'professional rugby league' to include the various professional competition nomenclatures over the last fifty years, including but not limited to NRL. In this correction article, the incorrect and correct information are published.

4.
Am J Forensic Med Pathol ; 25(4): 324-6, 2004 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-15577522

RESUMEN

A 70-year-old male patient with a 23-year-old history of right lower lung lobectomy for primary pulmonary adenocarcinoma (T1 N0 M0) presented with recurrent bronchopneumonia and purulent sputum. Pleural callus, lung abscess, bronchopleural fistula, and stitch granulomas were confirmed by chest x-ray, computed tomography scan, and bronchoscopy in the background of his complaints. An attempt to remove the bronchial purulent discharge and tissue sampling was made by using a flexible bronchoscope. The area of the lower trachea suddenly became clogged during bronchoscopic removal of the suspected piece of tissue (which later turned out to be organizing surgical gauze). The resuscitation following ventricular fibrillation failed to save the patient's life. The forensic postmortem examination confirmed the position of the foreign body extending from the abscess cavity, crossing the midline at carina and obstructing the lower trachea. This foreign body was a remnant of the surgical gauze left behind during a thoracic surgery 23 years ago.


Asunto(s)
Asfixia/diagnóstico , Migración de Cuerpo Extraño/diagnóstico , Tapones Quirúrgicos de Gaza , Adenocarcinoma/cirugía , Anciano , Asfixia/diagnóstico por imagen , Asfixia/patología , Diagnóstico Diferencial , Resultado Fatal , Migración de Cuerpo Extraño/diagnóstico por imagen , Migración de Cuerpo Extraño/patología , Humanos , Neoplasias Pulmonares/cirugía , Masculino , Tomografía Computarizada por Rayos X
5.
Toxicol Sci ; 77(2): 368-74, 2004 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-14657520

RESUMEN

Tinuvin 770 [bis(2,2,6,6-tetramethyl-4-piperidinyl) sebacate], is a UV light stabilizer plastic additive used worldwide. It is a component of many plastic materials used in medical and food industries. Earlier studies demonstrated its in vitro L-type Ca2+ channel and nicotinic acetylcholine receptor blocking properties. Our previous experiments have proved the toxic effects of Tinuvin 770 on isolated rat cardiomyocytes. The present study investigates the cardiotoxic effects of Tinuvin 770 in vivo. Wistar rats were intraperitoneally injected with increasing doses of Tinuvin 770 (1, 10, 100 microg, and 1 mg) 15 times during a 5-week period. Myocardial samples were analyzed by light, electron, and fluorescent microscopy. The lead-acetate method was used to detect intracellular Ca2+, and glyoxylic acid technique to assess alteration in adrenergic innervation. Focal myocytolysis and hypercontraction necrosis could be observed in rats treated with higher doses of Tinuvin 770. In these groups, intracellular Ca2+ accumulation and increased catecholamine release were detected. Tinuvin 770 not only displays L-type Ca2+ channel blocking properties, but can also lead to catecholamine release, similar to effects of the first generation of L-type Ca2+ channel blockers. Morphological results correspond to catecholamine-induced myocardial damage. Current literature, as well as our study, indicates that more detailed toxicological analysis of Tinuvin 770 should be required, and current regulations in medical and food industries should adopt the new results.


Asunto(s)
Bloqueadores de los Canales de Calcio/toxicidad , Ácidos Decanoicos/toxicidad , Corazón/efectos de los fármacos , Miocardio/patología , Piperidinas/toxicidad , Plásticos/química , Animales , Calcio/análisis , Calcio/metabolismo , Bloqueadores de los Canales de Calcio/administración & dosificación , Canales de Calcio Tipo L/efectos de los fármacos , Ácidos Decanoicos/administración & dosificación , Ácidos Decanoicos/química , Relación Dosis-Respuesta a Droga , Equipos y Suministros , Femenino , Inyecciones Intraperitoneales , Masculino , Miocardio/ultraestructura , Necrosis , Norepinefrina/orina , Piperidinas/administración & dosificación , Piperidinas/química , Ratas , Ratas Wistar
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA