Human fetal and adult spleen phospholipids and their fatty acid composition.

Total phospholipid contents and the individual phospholipid components of human adult and fetal spleens from 17--18 and 23--24 week's pregnancies composition of sphingomyelin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, diphosphatidylglycerol and phosphatidic acid studied in human adult, 17--18 and 23--24 week fetal spleens.

[Investigations of amniotic fluid after intraamnial application of prostaglandin F 2 alpha (author's transl)]. / Fruchtwasseruntersuchungen nach intraamnialer Applikation von Prostaglandin F 2 alpha

PIP: In 11 cases of abortion induced by (PGF2alpha) prostaglandin F2alpha, the authors studied the cinetic behavior of PGF2alpha in amniotic fluid using gas chromatography. In early pregnancy, the biologic 1/2-life is shorter than in later pregnancy. They assume that considerable paraplacentar diffusion is the reason for this. Cinetic investigations suggest that the vital functions of the fetus remain unchanged until it is expelled. There was no time correlation between the 1/2-life time and time of induction of abortion. (author's)^ieng

Interruption of pregnancy by PGF 2 alpha. II. Extraovular administration.

PIP: The prostaglandin PGF2alpha was administered extraovularly to 38 health women aged 17-37 to induce abortion. The women were in the first trimester of pregnancy. The prostaglandin was given every 2nd hour in doses of 250-1000 mcg, depending on the frequency and intensity of the uterine contractions and on the side effects. Abortion took place within 36 hours (mean, 21.6 hours) in 26 (68.4%) of the cases. The quantity of PGF2alpha administered was 2.25-14.75 mg, with an average of 6.72 mg. Side effects (most notably, vomiting and diarrhea) occurred in 27 cases, but they did not interrupt the intermittent PG treatment. No essential changes in the results of laboratory tests were noted.^ieng