1.
J Investig Med High Impact Case Rep
; 11: 23247096231172467, 2023.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37232266
RESUMEN
This is a case report of a previously healthy female patient with complement-mediated thrombotic microangiopathy (TMA) caused by a systemic cytomegalovirus infection that was successfully treated with plasmapheresis, steroids, and parenteral valganciclovir. Complement-mediated TMA is the result of various genetic mutations leading to complement abnormalities with overactivation of alternate complement pathway in response to a triggering infection. She also had splenic rupture without splenomegaly and was managed successfully without splenectomy.