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3.
Arch Pathol Lab Med ; 128(5): 574-7, 2004 May.
Artículo en Inglés | MEDLINE | ID: mdl-15086298

RESUMEN

Histoplasma capsulatum is a dimorphic fungus endemic to North America. Histoplasmosis is primarily an inhalation-acquired mycosis that is encountered rarely outside of endemic regions. In nonendemic regions, histoplasmosis may present a diagnostic challenge and both clinical and laboratory vigilance are required to accurately identify infection. Unusual clinical presentations with limited physical findings may compound the difficulty in diagnosis. We describe a 78-year-old retired soil science professor who presented with an eroded epiglottic mass secondary to disseminated histoplasmosis in a nonendemic region (Alberta). Clinically, this mass was thought to represent a primary laryngeal carcinoma, as no other buccal or oropharyngeal ulcers were identified. Histoplasmosis was confirmed by tissue biopsy and a positive immunodiffusion test for immunoglobulin G. Disseminated histoplasmosis is often associated with laryngeal and oropharyngeal disease; however, isolated epiglottic histoplasmosis is rare. Histoplasmosis should be included in the differential diagnosis of neoplasms and chronic ulcers of the upper aerodigestive tract.


Asunto(s)
Epiglotis , Histoplasmosis/patología , Anciano , Alberta/epidemiología , Carcinoma/diagnóstico , Diagnóstico Diferencial , Enfermedades Endémicas , Epiglotis/patología , Histoplasmosis/diagnóstico , Histoplasmosis/epidemiología , Humanos , Neoplasias Laríngeas/diagnóstico , Masculino
4.
Clin Infect Dis ; 37(7): e100-1, 2003 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-13130418

RESUMEN

A 61-year-old previously healthy man developed chronic dermal granulomata in his right arm after receiving a coral injury in Thailand. After 7 biopsies, infection caused by Mycobacterium haemophilum was diagnosed. This case highlights the difficulty of isolating this fastidious organism in the laboratory and suggests that seawater or coral was the source of the infection.


Asunto(s)
Antozoos/microbiología , Infecciones por Mycobacterium/microbiología , Mycobacterium haemophilum/aislamiento & purificación , Enfermedades de la Piel/microbiología , Humanos , Masculino , Persona de Mediana Edad , Tailandia , Microbiología del Agua
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