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1.
Artículo en Inglés | MEDLINE | ID: mdl-36901419

RESUMEN

In this study, electric field and magnetic flux density pollution levels were measured in southern Africa, a case of Blantyre City in Malawi, between 2020 and 2021. Sixty short-term measurements were performed using Trifield Electro Magnetic Frequency meter model TF2 in 30 different locations. Five high-population-dense sampling points were selected from school campuses, hospitals, industrial areas, markets, residential areas, and within the commercial and business center (CBC) of Blantyre. Electric field and magnetic flux density pollution monitoring was conducted between 10:00-12:00 h and 17:00-19:00 h for short-range analysis. Short-range results show that the maximum measured electric field pollution were 249.24 mV/m and 207.85 mV/m between 10:00-12:00 and 17:00-19:00 respectively, which are below the public limits of 4200.00 mV/m for public exposure. Similarly, maximum short-range results for magnetic flux density were 0.073 G and 0.057 G between 10:00-12:00 and 17:00-19:00 respectively which are below the public limits of 2 G for public exposure. Both measured electric and magnetic flux density were compared with the International Commission on Non-Ionizing Radiation Protection (ICNIRP), World health organization (WHO), and Institute of electrical and electronics engineers (IEEE). It was determined that all measured values for both electric and magnetic flux density were smaller than set limits for non-ionizing radiation for both public and occupation health. More importantly, these background measurements establish a baseline for future changes to be compared against public safety.


Asunto(s)
Electricidad , Campos Electromagnéticos , Malaui , Exposición a Riesgos Ambientales , África Austral
2.
Anticancer Agents Med Chem ; 22(8): 1622-1631, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-34238201

RESUMEN

BACKGROUND: In Malawi, cancer is one of the leading causes of morbidity and mortality. This has led to increased use of herbal medicines for cancer management. OBJECTIVE: This study aimed at identifying medicinal plants that are used for the management of cancer in the southern area of Karonga district, Northern Malawi. METHODS: Semi-structured individual questionnaire interviews were used to collect ethnobotanical data from traditional herbal practitioners in the study area. RESULTS: A total of twenty six (26) plant species from seventeen (17) botanical families were reported by Traditional Herbal Practitioners to be effective in the management of cancer. The botanical families with representation of more than one plant species were Fabaceae with five species, followed by Combretaceae and the Anacardiaceae with three species each, and Meliaceaewith with two species. The relative frequency of citation (RFC) showed that Senna singueana (RFC = 0.833), Lannea discolour (RFC = 0.833), Melia azedarach (RFC = 0.667), and Moringa oleifera (RFC = 0.667) were the medicinal plant species which were frequently mentioned and used in the study. The recipes could be a mixture of plant species or plant parts such as the leaves, barks, roots, rhizomes, seeds, flowers, and fruits. CONCLUSION: The study showed that a potential cancer management drug could be developed from the medicinal plant species found in the area. The results of this study could provide baseline information on medicinal plant species for further phytochemical studies and other studies to validate their use.


Asunto(s)
Neoplasias , Plantas Medicinales , Etnobotánica/métodos , Humanos , Malaui , Neoplasias/tratamiento farmacológico , Fitoterapia/métodos , Encuestas y Cuestionarios
3.
Malawi Med J ; 33(2): 85-107, 2021 06.
Artículo en Inglés | MEDLINE | ID: mdl-34777704

RESUMEN

The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered an international pandemic that has led to significant public health problems. To date, limited evidence exists to suggest that drugs are effective against the disease. As possible treatments are being investigated, herbal medicines have shown potential for producing novel antiviral agents for the COVID-19 disease. Aim: This review explored the potential of Malawi's traditional medicinal plants for the management of COVID-19. Methods: The authors searched on PubMed and Google scholar for medicinal plants that are used in Malawi and published in openly available peer reviewed journals. Plants linked with antiviral treatment, anti-COVID-19 activity or COVID-19 symptoms management were targeted. These included activity against pneumonia, inflammation, cough, difficulty in breathing, pain/aches, fever, diarrhoea, rheumatism, fatigue, asthma, immunocompromised and cardiovascular diseases. Results: 11 studies were found with 306 plant species. 127 plant species had at least one COVID-19 related pharmacological activity. Of these plant species, the number of herbal entities used for each indication was: pain/aches (87), fever (2), pneumonia (9), breathing/asthma problems (5), coughing (11), diarrhoea (1), immunosuppression (8), blood issues (10), fatigue (2), heart problems (11), inflammation (8), rheumatism (10) and viral diseases (12). Thirty (30) species were used for more than one disease and Azedarachta indica topped the list (6 of the 13 COVID-19 related diseases). The majority of the species had phytochemicals known to have antiviral activity or mechanisms of actions linked to COVID-19 and consequent diseases' treatment pathways. Conclusion: Medicinal plants are a promising source of compounds that can be used for drug development of COVID-19 related diseases. This review highlights potential targets for the World Health Organization and other research entities to explore in order to assist in controlling the pandemic.


Asunto(s)
COVID-19 , Plantas Medicinales , Antivirales/uso terapéutico , Humanos , Malaui , Fitoquímicos , SARS-CoV-2
4.
Malawi med. j. (Online) ; 33(2): 85-107, 2021.
Artículo en Inglés | AIM (África) | ID: biblio-1284519

RESUMEN

The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered an international pandemic that has led to significant public health problems. To date, limited evidence exists to suggest that drugs are effective against the disease. As possible treatments are being investigated, herbal medicines have shown potential for producing novel antiviral agents for the COVID-19 disease. Aim This review explored the potential of Malawi's traditional medicinal plants for the management of COVID-19. Methods:The authors searched on PubMed and Google scholar for medicinal plants that are used in Malawi and published in openly available peer reviewed journals. Plants linked with antiviral treatment, anti-COVID-19 activity or COVID-19 symptoms management were targeted. These included activity against pneumonia, inflammation, cough, difficulty in breathing, pain/aches, fever, diarrhoea, rheumatism, fatigue, asthma, immunocompromised and cardiovascular diseases.Results:11 studies were found with 306 plant species. 127 plant species had at least one COVID-19 related pharmacological activity. Of these plant species, the number of herbal entities used for each indication was: pain/aches (87), fever (2), pneumonia (9), breathing/asthma problems (5), coughing (11), diarrhoea (1), immunosuppression (8), blood issues (10), fatigue (2), heart problems (11), inflammation (8), rheumatism (10) and viral diseases (12). Thirty (30) species were used for more than one disease and Azedarachta indica topped the list (6 of the 13 COVID-19 related diseases). The majority of the species had phytochemicals known to have antiviral activity or mechanisms of actions linked to COVID-19 and consequent diseases' treatment pathways.Conclusion:Medicinal plants are a promising source of compounds that can be used for drug development of COVID-19 related diseases. This review highlights potential targets for the World Health Organization and other research entities to explore in order to assist in controlling the pandemic.


Asunto(s)
Humanos , Medicinas Tradicionales Africanas , COVID-19 , Preparaciones de Plantas , Malaui , Medicina Tradicional
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