Asunto(s)
Puente de Arteria Coronaria , Hemorragia Gastrointestinal/etiología , Inhibidores de Agregación Plaquetaria/efectos adversos , Complicaciones Posoperatorias/etiología , Ticlopidina/análogos & derivados , Anciano , Arteriolas/anomalías , Clopidogrel , Humanos , Masculino , Estómago/irrigación sanguínea , Ticlopidina/efectos adversosAsunto(s)
Humanos , Masculino , Persona de Mediana Edad , Hemorragia Gastrointestinal/complicaciones , Hemorragia Gastrointestinal/diagnóstico , Complicaciones Posoperatorias/patología , Complicaciones Posoperatorias/cirugía , Gastroscopía , Inhibidores de la Bomba de Protones/uso terapéutico , Profármacos/uso terapéutico , Complicaciones Posoperatorias/tratamiento farmacológico , Complicaciones Posoperatorias/fisiopatología , Revascularización Miocárdica , Profármacos/metabolismo , Profármacos/farmacocinéticaRESUMEN
The purpose of this study was to determine the toxic effects of polluted sediments, mainly chromium, the El Niagara reservoir (Aguascalientes, Mexico) on a benthic oligochaete species. Acute toxicity tests with hexavalent chromium in an artificial sediment-water system resulted in 24-, 48-, and 96-h LC50 values of 49.53, 22.81, and 5.11 mg available chromium/kg dry sediment, respectivley, in Limnodrilus hoffmeisteri. The uptake of chromium by tubificids from artificial and polluted reservoir sediments was found to increase with metal concentration in sediments and exposure time. The increase was higher in experiments with artificial sediment. Cr concentration in worms was related to hemoglobin content, which decreased significantly when Cr concentrations were above 1.0 microg/g dry weight. Bioavailable chromium in the El Niágara reservoir sediments may be an important factor limiting the benthic species in this ecosystem.